BindingDB PrimarySearch

Found 21 hits of ec50 data for polymerid = 49000286,49000287,50000022,50002695
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50413782 (CHEMBL1627325) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0339	n/a	n/a	n/a	n/a
National Institute of Neuroscienc Curated by ChEMBL					Assay Description Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calc...				J Med Chem 52: 4068-71 (2009) Article DOI: 10.1021/jm900604g BindingDB Entry DOI: 10.7270/Q2445NQD
National Institute of Neuroscienc Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50049949 ((BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH \| (b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0490	n/a	n/a	n/a	n/a
National Institute of Neuroscienc Curated by ChEMBL					Assay Description Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calc...				J Med Chem 52: 4068-71 (2009) Article DOI: 10.1021/jm900604g BindingDB Entry DOI: 10.7270/Q2445NQD
National Institute of Neuroscienc Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50075000 ((E)-N-({[4-Chloro-2-cyano-3-(2-methyl-quinolin-8-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074984 ((E)-N-({[2,4-Dichloro-3-(2-methyl-benzothiazol-4-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074982 ((E)-N-({[2,4-Dichloro-3-(2-methyl-benzothiazol-4-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074992 ((E)-N-({[4-Chloro-2-methoxy-3-(2-methyl-quinolin-8...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074986 ((E)-N-({[4-Chloro-2-cyano-3-(2-methyl-quinolin-8-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074997 ((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[4-methoxy-...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074980 ((E)-N-({[2,4-Dichloro-3-(2-methyl-benzothiazol-4-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074983 ((E)-N-({[2-Chloro-4-methoxy-3-(2-methyl-quinolin-8...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074998 ((E)-N-({[4-Methoxy-3-(2-methyl-quinolin-8-yloxymet...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074991 ((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074999 (CHEMBL114180 \| N-[4-Chloro-2-cyano-3-(2-methyl-qui...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074978 (2-[3-(4-Amino-butyl)-ureido]-N-[4-chloro-2-cyano-3...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074990 (4-[3-({[4-Chloro-2-cyano-3-(2-methyl-quinolin-8-yl...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074987 (CHEMBL113502 \| N-[2-Cyano-4-methoxy-3-(2-methyl-qu...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074994 (5-[({[4-Methoxy-3-(2-methyl-quinolin-8-yloxymethyl...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074979 ((E)-3-(4-Methoxy-phenyl)-N-({methyl-[3-(2-methyl-q...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074995 ((E)-N-({[2-Methoxy-3-(2-methyl-quinolin-8-yloxymet...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074988 ((E)-N-({[3-(Benzothiazol-4-yloxymethyl)-2,4-dichlo...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Cavia porcellus)	BDBM50074989 ((E)-N-({[2,4-Dichloro-3-(2-phenyl-benzothiazol-4-y...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Hoechst Marion Roussel GmbH Curated by ChEMBL					Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C
Hoechst Marion Roussel GmbH Curated by ChEMBL					More data for this Ligand-Target Pair