Compile Data Set for Download or QSAR

Found 61 hits of ic50 data for polymerid = 2395,4691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50590284 (CHEMBL5192316) Show SMILES O=C(Nc1ncc(s1)-c1ccc(cc1)C#C)[C@H]1CCN(C1)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00218j BindingDB Entry DOI: 10.7270/Q27S7SQ9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50590283 (CHEMBL5169766 | US20230303547, Reference Example D) Show SMILES O=C(Nc1ncc(s1)-c1ccccc1)[C@H]1CCN(C1)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00218j BindingDB Entry DOI: 10.7270/Q27S7SQ9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50431630 (KRX-0401 | PERIFOSINE) Show SMILES CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1 Show InChI InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM53421 (4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...) Show SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C20H20N2/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)21-20(22-19)16-11-5-2-6-12-16/h2,5-8,11-15H,1,3-4,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594731 (CHEMBL1241028) Show SMILES Clc1c2C(=O)CC(=O)c2c(Cl)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53421 (4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...) Show SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C20H20N2/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)21-20(22-19)16-11-5-2-6-12-16/h2,5-8,11-15H,1,3-4,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50069764 (CHEMBL3407501) Show SMILES Fc1ccc(cc1)-c1nc2c(o1)C(=O)c1ccccc1C2=O Show InChI InChI=1S/C17H8FNO3/c18-10-7-5-9(6-8-10)17-19-13-14(20)11-3-1-2-4-12(11)15(21)16(13)22-17/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594730 (CHEMBL5193983) Show SMILES COC(=O)c1cc(c(N)c(n1)-c1ccc2C(=O)C(OC)=C(N)C(=O)c2n1)-c1ccc(OC)c(OC)c1O |t:20| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50538571 (CHEMBL4635160) Show SMILES C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r| Show InChI InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594729 (CHEBI:27485 | CHEMBL1397260) Show SMILES CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)C=CC1=O |c:20| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM65518 (5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12 |w:4.3| Show InChI InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50442907 (Acetyl Isogambogic Acid | CHEMBL3039433) Show SMILES [H]C12[#6]-[#6@H]-3-[#6]=[#6]4-[#6](=O)-c5c(-[#8]-[#6](-[#6])=O)c6-[#6]=[#6]C([#6])([#6]-[#6]\[#6]=[#6](\[#6])-[#6])[#8]-c6c(-[#6]\[#6]=[#6](\[#6])-[#6])c5-[#8][C@@]14C([#6]\[#6]=[#6](/[#6])-[#6](-[#8])=O)([#8]C2([#6])[#6])[#6]-3=O |r,c:15,t:4,TLB:34:35:44.45:48.3.2,4:3:35:44.45,THB:5:35:44.45:48.3.2,49:48:35:44.45,45:1:5.4:36.48| Show InChI InChI=1S/C40H46O9/c1-21(2)11-10-16-38(9)17-15-27-32(47-38)26(13-12-22(3)4)34-30(33(27)46-24(6)41)31(42)28-19-25-20-29-37(7,8)49-39(35(25)43,40(28,29)48-34)18-14-23(5)36(44)45/h11-12,14-15,17,19,25,29H,10,13,16,18,20H2,1-9H3,(H,44,45)/b23-14+/t25-,29?,38?,39?,40-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53469 (MLS001209351 | N-[1-(4-Bromo-phenyl)-ethylidene]-N...) Show SMILES CC(N=Nc1cc(nc(C)n1)N1CCCCC1)c1ccc(Br)cc1 |w:3.3| Show InChI InChI=1S/C18H22BrN5/c1-13(15-6-8-16(19)9-7-15)22-23-17-12-18(21-14(2)20-17)24-10-4-3-5-11-24/h6-9,12-13H,3-5,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326012 (3-(acetoxyimino)-5-bromo-1-(3,4-dichlorobenzyl)ind...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(Br)cc12 |w:4.3| Show InChI InChI=1S/C17H11BrCl2N2O3/c1-9(23)25-21-16-12-7-11(18)3-5-15(12)22(17(16)24)8-10-2-4-13(19)14(20)6-10/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53467 (1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...) Show SMILES CCCOc1ccc(\C=C\c2c([N+]([O-])=O)c(=O)n(C)c(=O)n2C)cc1 Show InChI InChI=1S/C17H19N3O5/c1-4-11-25-13-8-5-12(6-9-13)7-10-14-15(20(23)24)16(21)19(3)17(22)18(14)2/h5-10H,4,11H2,1-3H3/b10-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53470 (2-N,2-N,4-N,4-N-tetraethyl-6-N-(4-nitrophenyl)-1,3...) Show SMILES CCN(CC)c1nc(Nc2ccc(cc2)[N+]([O-])=O)nc(n1)N(CC)CC Show InChI InChI=1S/C17H25N7O2/c1-5-22(6-2)16-19-15(20-17(21-16)23(7-3)8-4)18-13-9-11-14(12-10-13)24(25)26/h9-12H,5-8H2,1-4H3,(H,18,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53443 (2-(3-chloro-4-methoxy-N-methylsulfonylanilino)-N-[...) Show SMILES COc1ccc(cc1Cl)N(CC(=O)NCCSCc1cccc(Cl)c1)S(C)(=O)=O Show InChI InChI=1S/C19H22Cl2N2O4S2/c1-27-18-7-6-16(11-17(18)21)23(29(2,25)26)12-19(24)22-8-9-28-13-14-4-3-5-15(20)10-14/h3-7,10-11H,8-9,12-13H2,1-2H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53468 (2-[3-cyano-4-(2-methoxyphenyl)-6-phenyl-pyridin-2-...) Show SMILES COc1ccccc1-c1cc(nc(SCC(O)=O)c1C#N)-c1ccccc1 Show InChI InChI=1S/C21H16N2O3S/c1-26-19-10-6-5-9-15(19)16-11-18(14-7-3-2-4-8-14)23-21(17(16)12-22)27-13-20(24)25/h2-11H,13H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326014 (3-(acetoxyimino)-1-(3,4-dichlorobenzyl)-5-iodoindo...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(I)cc12 |w:4.3| Show InChI InChI=1S/C17H11Cl2IN2O3/c1-9(23)25-21-16-12-7-11(20)3-5-15(12)22(17(16)24)8-10-2-4-13(18)14(19)6-10/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53416 ((2S)-2-[[4-[(4-chlorophenyl)carbamoyl]-1H-imidazol...) Show SMILES CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1[nH]cnc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C24H25ClN4O4/c1-24(2,3)33-23(32)18(13-15-7-5-4-6-8-15)29-22(31)20-19(26-14-27-20)21(30)28-17-11-9-16(25)10-12-17/h4-12,14,18H,13H2,1-3H3,(H,26,27)(H,28,30)(H,29,31)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM200235 (Rifampicin | cid_5381226) Show SMILES CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2C(=O)\C(=C\NN4CCN(C)CC4)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C(O)c2c(O)c3C |wU:45.47,41.43,37.39,43.45,35.37,6.6,wD:2.1,39.41,50.53,c:33,t:3,35,54,(15.1,-5.61,;13.64,-5.11,;13.35,-3.6,;14.73,-2.92,;16.01,-3.78,;17.39,-3.1,;17.5,-1.56,;18.99,-1.94,;18.12,-.17,;16.98,.86,;15.65,.09,;15.97,-1.41,;16.45,-2.87,;14.32,.86,;12.94,.04,;14.28,-.72,;11.54,.83,;10.21,.05,;9.44,1.38,;9.43,2.92,;8.1,3.69,;8.09,5.23,;9.42,6,;9.42,7.54,;10.76,5.24,;10.76,3.7,;11.54,2.43,;10.16,1.76,;9.14,.62,;9.33,-.91,;7.86,1.48,;7.43,2.96,;6.47,.8,;6.37,-.73,;4.99,-1.41,;4.49,-2.87,;3.08,-2.24,;5.5,-4.03,;4.48,-5.18,;7.04,-4.13,;6.8,-5.65,;7.9,-2.85,;7.67,-1.33,;9.41,-2.56,;10.9,-2.2,;10.69,-3.42,;10.98,-4.93,;10.48,-6.38,;11.5,-7.54,;8.97,-6.68,;12.07,-2.74,;13.58,-2.44,;12.94,3.22,;12.96,4.76,;14.32,2.4,;15.65,3.17,;15.65,4.71,;16.98,2.4,;18.32,3.17,)| Show InChI InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,44,49-51,53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,28-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53442 ((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...) Show SMILES Cc1c(oc2c(Cl)cc(C)cc12)C(=O)N1CCC(O)(CC1)c1ccccc1 Show InChI InChI=1S/C22H22ClNO3/c1-14-12-17-15(2)19(27-20(17)18(23)13-14)21(25)24-10-8-22(26,9-11-24)16-6-4-3-5-7-16/h3-7,12-13,26H,8-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53441 (MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...) Show SMILES Clc1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1 Show InChI InChI=1S/C14H10ClN3O/c15-10-5-3-4-9(8-10)13(19)18-14-16-11-6-1-2-7-12(11)17-14/h1-8H,(H2,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594733 (CHEMBL4303698) Show SMILES CC(=O)O\N=C1\C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326013 (3-(acetoxyimino)-5-bromo-1-(2,5-dichlorobenzyl)ind...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Br)cc12 |w:4.3| Show InChI InChI=1S/C17H11BrCl2N2O3/c1-9(23)25-21-16-13-7-11(18)2-5-15(13)22(17(16)24)8-10-6-12(19)3-4-14(10)20/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53449 (4-(4-bromophenyl)-2-(o-toluoylamino)-3-thenoic aci...) Show SMILES Cc1ccccc1C(=O)Nc1scc(c1C(O)=O)-c1ccc(Br)cc1 Show InChI InChI=1S/C19H14BrNO3S/c1-11-4-2-3-5-14(11)17(22)21-18-16(19(23)24)15(10-25-18)12-6-8-13(20)9-7-12/h2-10H,1H3,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53413 ((2S)-2-[[[4-[(4-methylanilino)-oxomethyl]-1H-imida...) Show SMILES Cc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C27H39N5O6/c1-17-11-13-18(14-12-17)31-22(33)20-21(30-16-29-20)23(34)32-19(24(35)37-26(2,3)4)10-8-9-15-28-25(36)38-27(5,6)7/h11-14,16,19H,8-10,15H2,1-7H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM205457 ((2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9...) Show SMILES CC1=C(O)C(=O)C=C2C1=CC=C1[C@@]2(C)CC[C@@]2(C)[C@@H]3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(O)=O |r,c:1,6,11,t:9| Show InChI InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53414 ((2S)-4-methyl-2-[[4-(m-tolylcarbamoyl)-1H-imidazol...) Show SMILES CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)Nc1cccc(C)c1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C25H28N4O4/c1-16(2)12-20(25(32)33-14-18-9-5-4-6-10-18)29-24(31)22-21(26-15-27-22)23(30)28-19-11-7-8-17(3)13-19/h4-11,13,15-16,20H,12,14H2,1-3H3,(H,26,27)(H,28,30)(H,29,31)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53445 (2-(4-hydroxy-3-nitro-benzylidene)-3-keto-5-(2-meth...) Show SMILES CCOC(=O)C1=C(C)N=c2s\c(=C/c3ccc(O)c(c3)[N+]([O-])=O)c(=O)n2C1c1ccccc1OC |c:5,t:8| Show InChI InChI=1S/C24H21N3O7S/c1-4-34-23(30)20-13(2)25-24-26(21(20)15-7-5-6-8-18(15)33-3)22(29)19(35-24)12-14-9-10-17(28)16(11-14)27(31)32/h5-12,21,28H,4H2,1-3H3/b19-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53482 (1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-ca...) Show SMILES CCCCn1c2ccccc2c(O)c(C(=O)NCc2ccccc2Cl)c1=O Show InChI InChI=1S/C21H21ClN2O3/c1-2-3-12-24-17-11-7-5-9-15(17)19(25)18(21(24)27)20(26)23-13-14-8-4-6-10-16(14)22/h4-11,25H,2-3,12-13H2,1H3,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594732 (CHEMBL5195092) Show SMILES CCCCc1ccc(cc1)-c1nnc(C)n1-c1ccc(cc1)C(C)C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53422 (2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...) Show SMILES COc1ccc2nc(nc(C3CCCCC3)c2c1)C1CCCCC1 Show InChI InChI=1S/C21H28N2O/c1-24-17-12-13-19-18(14-17)20(15-8-4-2-5-9-15)23-21(22-19)16-10-6-3-7-11-16/h12-16H,2-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326015 (5-(4-butylphenyl)-4-(4-isopropylphenyl)-4H-1,2,4-t...) Show SMILES CCCCc1ccc(cc1)-c1n[nH]c(=S)n1-c1ccc(cc1)C(C)C Show InChI InChI=1S/C21H25N3S/c1-4-5-6-16-7-9-18(10-8-16)20-22-23-21(25)24(20)19-13-11-17(12-14-19)15(2)3/h7-15H,4-6H2,1-3H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53447 (4,4'-[1,4-phenylenebis(oxy)]diphenol | 4-[4-(4...) Show SMILES Oc1ccc(Oc2ccc(Oc3ccc(O)cc3)cc2)cc1 Show InChI InChI=1S/C18H14O4/c19-13-1-5-15(6-2-13)21-17-9-11-18(12-10-17)22-16-7-3-14(20)4-8-16/h1-12,19-20H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53419 ((2S)-2-[[4-[(4-methoxyphenyl)carbamoyl]-1H-imidazo...) Show SMILES COc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](CC(C)C)C(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C22H30N4O5/c1-13(2)11-16(21(29)31-22(3,4)5)26-20(28)18-17(23-12-24-18)19(27)25-14-7-9-15(30-6)10-8-14/h7-10,12-13,16H,11H2,1-6H3,(H,23,24)(H,25,27)(H,26,28)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53415 ((2S)-2-[[4-(m-tolylcarbamoyl)-1H-imidazole-5-carbo...) Show SMILES Cc1cccc(NC(=O)c2nc[nH]c2C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)c1 Show InChI InChI=1S/C25H28N4O4/c1-16-9-8-12-18(13-16)28-22(30)20-21(27-15-26-20)23(31)29-19(24(32)33-25(2,3)4)14-17-10-6-5-7-11-17/h5-13,15,19H,14H2,1-4H3,(H,26,27)(H,28,30)(H,29,31)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53454 ((2E)-2-[(2Z)-2-(3-methoxy-4-oxidanylidene-cyclohex...) Show SMILES COc1ccc(cc1)-n1c(C=Cc2ccc(O)c(OC)c2)nc2ccccc2c1=O |w:10.10| Show InChI InChI=1S/C24H20N2O4/c1-29-18-11-9-17(10-12-18)26-23(25-20-6-4-3-5-19(20)24(26)28)14-8-16-7-13-21(27)22(15-16)30-2/h3-15,27H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50242207 (CHEMBL455364 | Mangiferin) Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc3oc4cc(O)c(O)cc4c(=O)c3c2O)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H18O12/c20-4-11-14(25)16(27)17(28)19(30-11)31-18-8(23)3-10-12(15(18)26)13(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,14,16-17,19-23,25-28H,4H2/t11-,14-,16+,17-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.26E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53418 ((2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imida...) Show SMILES CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)c1nc[nH]c1C(=O)Nc1ccc(Cl)cc1)C(=O)OC(C)(C)C Show InChI InChI=1S/C26H36ClN5O6/c1-25(2,3)37-23(35)18(9-7-8-14-28-24(36)38-26(4,5)6)32-22(34)20-19(29-15-30-20)21(33)31-17-12-10-16(27)11-13-17/h10-13,15,18H,7-9,14H2,1-6H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O |t:1| Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O |t:1| Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O |t:1| Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53471 ((3-Ethyl-5-hydroxy-5-phenyl-4,5-dihydro-pyrazol-1-...) Show SMILES CCC1=NN(C(=O)c2ccccc2O)C(O)(C1)c1ccccc1 |t:2| Show InChI InChI=1S/C18H18N2O3/c1-2-14-12-18(23,13-8-4-3-5-9-13)20(19-14)17(22)15-10-6-7-11-16(15)21/h3-11,21,23H,2,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50552483 (CHEMBL4763594) Show SMILES Nc1ccc(cc1)-c1cn(Cc2cc(cc(c2)-c2cccc(c2)C(O)=O)C(O)=O)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human UCHL3 assessed as reduction in cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115931 BindingDB Entry DOI: 10.7270/Q2R49VFD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50538549 (CHEMBL4641424) Show SMILES Nc1cc(ccn1)-c1cc(Cl)cc2CC(Oc12)C(=O)N1CCNCC1 Show InChI InChI=1S/C18H19ClN4O2/c19-13-7-12-8-15(18(24)23-5-3-21-4-6-23)25-17(12)14(10-13)11-1-2-22-16(20)9-11/h1-2,7,9-10,15,21H,3-6,8H2,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50270667 (CHEMBL4130194) Show SMILES CC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C24H27N3O3/c1-18(15-19-7-3-2-4-8-19)22(28)26-13-11-24(30,12-14-26)16-27-17-25-21-10-6-5-9-20(21)23(27)29/h2-10,17-18,30H,11-16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23421 (1-benzyl-3-hydroxy-4-[(5-methylfuran-2-yl)carbonyl...) Show SMILES Cc1ccc(o1)C(=O)C1C(N(Cc2ccccc2)C(=O)C1=O)c1cccnc1 Show InChI InChI=1S/C22H18N2O4/c1-14-9-10-17(28-14)20(25)18-19(16-8-5-11-23-12-16)24(22(27)21(18)26)13-15-6-3-2-4-7-15/h2-12,18-19H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53448 (1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...) Show SMILES CN(N)c1nc(cc(n1)-c1ccc(C)cc1)-c1ccccc1 Show InChI InChI=1S/C18H18N4/c1-13-8-10-15(11-9-13)17-12-16(14-6-4-3-5-7-14)20-18(21-17)22(2)19/h3-12H,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+5	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50069762 (CHEMBL3182437 | ML323 | US9802904, 87) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-n2ccnn2)n1 Show InChI InChI=1S/C23H24N6/c1-16(2)20-6-4-5-7-21(20)23-24-14-17(3)22(27-23)25-15-18-8-10-19(11-9-18)29-13-12-26-28-29/h4-14,16H,15H2,1-3H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair

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