Compile Data Set for Download or QSAR

Found 306 hits of ic50 data for polymerid = 2744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of MST2				J Med Chem 52: 3191-204 (2009) Article DOI: 10.1021/jm800861c BindingDB Entry DOI: 10.7270/Q23J3DWT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MST2 using MBP as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Inhibition of STK3 (unknown origin)				Eur J Med Chem 141: 657-675 (2017) Article DOI: 10.1016/j.ejmech.2017.10.003 BindingDB Entry DOI: 10.7270/Q2CV4M86
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human MST2 using MBP as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human MST2 using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50059277 (CHEMBL3393348 | US9156845, 4) Show SMILES N#Cc1cccc(c1)-c1c[nH]c2ncnc(N3CCOCC3)c12 Show InChI InChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant MST2 using Ser/Thr peptide 7 substrate after 45 mins by Z-Lyte assay				J Med Chem 58: 419-32 (2015) Article DOI: 10.1021/jm5014055 BindingDB Entry DOI: 10.7270/Q2XS5X2W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50583984 (CHEMBL5089935) Show SMILES CC(=O)NC1CCN(CC1)c1ncnc2[nH]cc(-c3cccc(Cl)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451766 (4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin...) Show SMILES COc1cc(ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1)S(=O)(=O)N(C)C1CC1 Show InChI InChI=1S/C25H26N4O4S/c1-29(18-4-5-18)34(31,32)19-6-8-20(23(13-19)33-2)17-12-22(24(26)28-14-17)15-3-7-21-16(11-15)9-10-27-25(21)30/h3,6-8,11-14,18H,4-5,9-10H2,1-2H3,(H2,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451761 (4-(6-amino-5-(1- oxoisoindolin-5-yl)pyridin-3- yl)...) Show SMILES CN(C1CC1)S(=O)(=O)c1ccc(c(F)c1)-c1cnc(N)c(c1)-c1ccc2C(=O)NCc2c1 Show InChI InChI=1S/C23H21FN4O3S/c1-28(16-3-4-16)32(30,31)17-5-7-18(21(24)10-17)15-9-20(22(25)26-11-15)13-2-6-19-14(8-13)12-27-23(19)29/h2,5-11,16H,3-4,12H2,1H3,(H2,25,26)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451719 (6-(2-amino-5-(2-fluoro-3- nitrophenyl)pyridin-3-yl...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1F)[N+]([O-])=O Show InChI InChI=1S/C20H15FN4O3/c21-18-14(2-1-3-17(18)25(27)28)13-9-16(19(22)24-10-13)11-4-5-15-12(8-11)6-7-23-20(15)26/h1-5,8-10H,6-7H2,(H2,22,24)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451730 (4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin...) Show SMILES CN(C1CC1)S(=O)(=O)c1ccc(c(F)c1)-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C24H23FN4O3S/c1-29(17-3-4-17)33(31,32)18-5-7-19(22(25)12-18)16-11-21(23(26)28-13-16)14-2-6-20-15(10-14)8-9-27-24(20)30/h2,5-7,10-13,17H,3-4,8-9H2,1H3,(H2,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50466038 (CHEMBL4281823) Show SMILES CCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H22F3N5O2/c1-2-32-13-19(22-23(29)30-14-31-24(22)32)16-6-7-20-17(12-16)8-9-33(20)21(34)11-15-4-3-5-18(10-15)35-25(26,27)28/h3-7,10,12-14H,2,8-9,11H2,1H3,(H2,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University/Collaborative Innovation Center of Biotherapy Curated by ChEMBL					Assay Description Inhibition of recombinant human MST2 (2 to end residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...				J Med Chem 61: 11398-11414 (2018) Article DOI: 10.1021/acs.jmedchem.8b01652 BindingDB Entry DOI: 10.7270/Q2377CDJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50583991 (CHEMBL5092052) Show SMILES CC(CO)CN(C)c1ncnc2[nH]cc(-c3cccc(Cl)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461415 (US10774068, Example 143 | US11427560, Example 143) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(Oc4ncccc4C)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H31ClN6O3/c1-5-39-27-16-25-22(15-26(27)35-28(38)9-7-13-37(3)4)29(20(17-32)18-34-25)36-24-11-10-21(14-23(24)31)40-30-19(2)8-6-12-33-30/h6,8,10-12,14-16,18H,5,7,9,13H2,1-4H3,(H,34,36)(H,35,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461368 (US10774068, Example 74 | US11427560, Example 74) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3Br)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33BrN6O3/c1-5-40-29-16-26-23(15-27(29)36-30(39)9-7-13-38(3)4)31(21(17-33)18-35-26)37-25-11-10-22(14-24(25)32)41-19-28-20(2)8-6-12-34-28/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,37)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461369 (US10774068, Example 75 | US11427560, Example 75) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4ncccc4C)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H32Cl2N6O3/c1-5-41-29-15-24-21(12-26(29)37-30(40)9-7-11-39(3)4)31(20(16-34)17-36-24)38-25-13-23(33)28(14-22(25)32)42-18-27-19(2)8-6-10-35-27/h6,8,10,12-15,17H,5,7,9,11,18H2,1-4H3,(H,36,38)(H,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461370 (US10774068, Example 76 | US11427560, Example 76) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4nc(Br)ccc4C)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H32BrClN6O3/c1-5-41-28-15-24-22(14-25(28)38-30(40)7-6-12-39(3)4)31(20(16-34)17-35-24)36-21-9-10-27(23(33)13-21)42-18-26-19(2)8-11-29(32)37-26/h8-11,13-15,17H,5-7,12,18H2,1-4H3,(H,35,36)(H,38,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461371 (US10774068, Example 77 | US11427560, Example 77) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4nc(Br)ccc4C)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H32BrClN6O3/c1-5-41-28-15-25-22(14-26(28)37-30(40)7-6-12-39(3)4)31(20(16-34)17-35-25)38-24-10-9-21(13-23(24)33)42-18-27-19(2)8-11-29(32)36-27/h8-11,13-15,17H,5-7,12,18H2,1-4H3,(H,35,38)(H,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461372 (US10774068, Example 78 | US11427560, Example 78) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4ncccc4C)cc3C)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C32H35ClN6O3/c1-6-41-30-16-26-23(14-27(30)37-31(40)10-8-12-39(4)5)32(22(17-34)18-36-26)38-25-15-24(33)29(13-21(25)3)42-19-28-20(2)9-7-11-35-28/h7,9,11,13-16,18H,6,8,10,12,19H2,1-5H3,(H,36,38)(H,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461373 (US10774068, Example 79 | US11427560, Example 79) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4ncccc4C)cc3Br)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H32BrClN6O3/c1-5-41-29-15-24-21(12-26(29)37-30(40)9-7-11-39(3)4)31(20(16-34)17-36-24)38-25-14-23(33)28(13-22(25)32)42-18-27-19(2)8-6-10-35-27/h6,8,10,12-15,17H,5,7,9,11,18H2,1-4H3,(H,36,38)(H,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461375 (US10774068, Example 81 | US11427560, Example 81) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C(F)(F)F)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H30ClF3N6O3/c1-4-43-28-15-25-21(14-26(28)39-29(42)8-6-12-41(2)3)30(19(16-36)17-38-25)40-24-10-9-20(13-23(24)32)44-18-27-22(31(33,34)35)7-5-11-37-27/h5,7,9-11,13-15,17H,4,6,8,12,18H2,1-3H3,(H,38,40)(H,39,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461377 (US10774068, Example 83 | US11427560, Example 83) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4CO)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33ClN6O4/c1-4-41-29-15-26-23(14-27(29)36-30(40)8-6-12-38(2)3)31(21(16-33)17-35-26)37-25-10-9-22(13-24(25)32)42-19-28-20(18-39)7-5-11-34-28/h5,7,9-11,13-15,17,39H,4,6,8,12,18-19H2,1-3H3,(H,35,37)(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461378 (US10774068, Example 84 | US11427560, Example 84) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(Cl)c3)c2cc1NC(C)=O Show InChI InChI=1S/C27H24ClN5O3/c1-4-35-26-12-22-20(11-23(26)32-17(3)34)27(18(13-29)14-31-22)33-19-7-8-25(21(28)10-19)36-15-24-16(2)6-5-9-30-24/h5-12,14H,4,15H2,1-3H3,(H,31,33)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461380 (US10774068, Example 90 | US11427560, Example 90) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C Show InChI InChI=1S/C31H31ClN6O3/c1-5-40-29-16-25-23(15-26(29)37-30(39)9-7-13-38(3)4)31(21(17-33)18-35-25)36-22-10-11-28(24(32)14-22)41-19-27-20(2)8-6-12-34-27/h6-12,14-16,18H,5,13,19H2,1-4H3,(H,35,36)(H,37,39)/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461381 (US10774068, Example 91 | US11427560, Example 91) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3Cl)c2cc1NC(=O)\C=C\CN(C)C Show InChI InChI=1S/C31H31ClN6O3/c1-5-40-29-16-26-23(15-27(29)36-30(39)9-7-13-38(3)4)31(21(17-33)18-35-26)37-25-11-10-22(14-24(25)32)41-19-28-20(2)8-6-12-34-28/h6-12,14-16,18H,5,13,19H2,1-4H3,(H,35,37)(H,36,39)/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461382 (US10774068, Example 92 | US11427560, Example 92) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(OC)c3)c2cc1NC(=O)\C=C\CN(C)C Show InChI InChI=1S/C32H34N6O4/c1-6-41-29-17-25-24(16-26(29)37-31(39)10-8-14-38(3)4)32(22(18-33)19-35-25)36-23-11-12-28(30(15-23)40-5)42-20-27-21(2)9-7-13-34-27/h7-13,15-17,19H,6,14,20H2,1-5H3,(H,35,36)(H,37,39)/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461383 (US10774068, Example 93 | US11427560, Example 93) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3C)c2cc1NC(=O)\C=C\CN(C)C Show InChI InChI=1S/C32H34N6O3/c1-6-40-30-17-27-25(16-28(30)36-31(39)10-8-14-38(4)5)32(23(18-33)19-35-27)37-26-12-11-24(15-22(26)3)41-20-29-21(2)9-7-13-34-29/h7-13,15-17,19H,6,14,20H2,1-5H3,(H,35,37)(H,36,39)/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461384 (US10774068, Example 94 | US11427560, Example 94) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cc(C)c(OCc4ncccc4C)cc3C)c2cc1NC(=O)\C=C\CN(C)C Show InChI InChI=1S/C33H36N6O3/c1-7-41-31-17-27-25(16-28(31)37-32(40)11-9-13-39(5)6)33(24(18-34)19-36-27)38-26-14-23(4)30(15-22(26)3)42-20-29-21(2)10-8-12-35-29/h8-12,14-17,19H,7,13,20H2,1-6H3,(H,36,38)(H,37,40)/b11-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461405 (US10774068, Example 127 | US11427560, Example 127) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cccc(Cl)c3)c2cc1NC(C)=O Show InChI InChI=1S/C20H17ClN4O2/c1-3-27-19-9-17-16(8-18(19)24-12(2)26)20(13(10-22)11-23-17)25-15-6-4-5-14(21)7-15/h4-9,11H,3H2,1-2H3,(H,23,25)(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461415 (US10774068, Example 143 | US11427560, Example 143) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(Oc4ncccc4C)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H31ClN6O3/c1-5-39-27-16-25-22(15-26(27)35-28(38)9-7-13-37(3)4)29(20(17-32)18-34-25)36-24-11-10-21(14-23(24)31)40-30-19(2)8-6-12-33-30/h6,8,10-12,14-16,18H,5,7,9,13H2,1-4H3,(H,34,36)(H,35,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P272CX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50335188 (CHEMBL1650545 | CHEMBL1650551 | N-[3-[(3,3-Difluor...) Show SMILES Cc1cn2c(cnc2c(Nc2cc(CN3CCC(F)(F)C3)ns2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C18H18F2N8S/c1-11-8-28-14(12-5-22-23-6-12)7-21-17(28)16(24-11)25-15-4-13(26-29-15)9-27-3-2-18(19,20)10-27/h4-8H,2-3,9-10H2,1H3,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MST2				J Med Chem 54: 201-10 (2011) Article DOI: 10.1021/jm1010995 BindingDB Entry DOI: 10.7270/Q2VM4D76
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50329198 (2-(ethyl((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1...) Show SMILES CCN(Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1)C(C)(C)CO Show InChI InChI=1S/C20H26N8OS/c1-5-27(20(3,4)12-29)11-15-6-17(30-26-15)25-18-19-21-9-16(14-7-22-23-8-14)28(19)10-13(2)24-18/h6-10,29H,5,11-12H2,1-4H3,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MST2				J Med Chem 54: 201-10 (2011) Article DOI: 10.1021/jm1010995 BindingDB Entry DOI: 10.7270/Q2VM4D76
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50335188 (CHEMBL1650545 | CHEMBL1650551 | N-[3-[(3,3-Difluor...) Show SMILES Cc1cn2c(cnc2c(Nc2cc(CN3CCC(F)(F)C3)ns2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C18H18F2N8S/c1-11-8-28-14(12-5-22-23-6-12)7-21-17(28)16(24-11)25-15-4-13(26-29-15)9-27-3-2-18(19,20)10-27/h4-8H,2-3,9-10H2,1H3,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MST2				J Med Chem 54: 201-10 (2011) Article DOI: 10.1021/jm1010995 BindingDB Entry DOI: 10.7270/Q2VM4D76
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461294 (US10774068, Example 1 | US11427560, Example 1) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33ClN6O3/c1-5-40-29-16-25-23(15-26(29)37-30(39)9-7-13-38(3)4)31(21(17-33)18-35-25)36-22-10-11-28(24(32)14-22)41-19-27-20(2)8-6-12-34-27/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461295 (US10774068, Example 2 | US11427560, Example 2) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cc(Cl)ccn4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30Cl2N6O3/c1-4-40-28-15-25-23(14-26(28)37-29(39)6-5-11-38(2)3)30(19(16-33)17-35-25)36-21-7-8-27(24(32)13-21)41-18-22-12-20(31)9-10-34-22/h7-10,12-15,17H,4-6,11,18H2,1-3H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461296 (US10774068, Example 3 | US11427560, Example 3) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(Br)n4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30BrClN6O3/c1-4-40-27-15-24-22(14-25(27)37-29(39)9-6-12-38(2)3)30(19(16-33)17-34-24)36-20-10-11-26(23(32)13-20)41-18-21-7-5-8-28(31)35-21/h5,7-8,10-11,13-15,17H,4,6,9,12,18H2,1-3H3,(H,34,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461297 (US10774068, Example 4 | US11427560, Example 4) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)n4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30ClFN6O3/c1-4-40-27-15-24-22(14-25(27)37-29(39)9-6-12-38(2)3)30(19(16-33)17-34-24)36-20-10-11-26(23(31)13-20)41-18-21-7-5-8-28(32)35-21/h5,7-8,10-11,13-15,17H,4,6,9,12,18H2,1-3H3,(H,34,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461300 (US10774068, Example 7 | US11427560, Example 7) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(Cl)n4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30Cl2N6O3/c1-4-40-27-15-24-22(14-25(27)37-29(39)9-6-12-38(2)3)30(19(16-33)17-34-24)36-20-10-11-26(23(31)13-20)41-18-21-7-5-8-28(32)35-21/h5,7-8,10-11,13-15,17H,4,6,9,12,18H2,1-3H3,(H,34,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461305 (US10774068, Example 11 | US11427560, Example 11) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccc(C)cn4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33ClN6O3/c1-5-40-29-15-26-24(14-27(29)37-30(39)7-6-12-38(3)4)31(21(16-33)18-35-26)36-22-10-11-28(25(32)13-22)41-19-23-9-8-20(2)17-34-23/h8-11,13-15,17-18H,5-7,12,19H2,1-4H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461306 (US10774068, Example 12 | US11427560, Example 12) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(C)n4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33ClN6O3/c1-5-40-29-16-26-24(15-27(29)37-30(39)10-7-13-38(3)4)31(21(17-33)18-34-26)36-22-11-12-28(25(32)14-22)41-19-23-9-6-8-20(2)35-23/h6,8-9,11-12,14-16,18H,5,7,10,13,19H2,1-4H3,(H,34,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461310 (US10774068, Example 15 | US11427560, Example 15) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4Br)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30BrClN6O3/c1-4-40-28-15-24-21(14-25(28)37-29(39)8-6-12-38(2)3)30(19(16-33)17-35-24)36-20-9-10-27(23(32)13-20)41-18-26-22(31)7-5-11-34-26/h5,7,9-11,13-15,17H,4,6,8,12,18H2,1-3H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461311 (US10774068, Example 16 | US11427560, Example 16) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4F)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C30H30ClFN6O3/c1-4-40-28-15-24-21(14-25(28)37-29(39)8-6-12-38(2)3)30(19(16-33)17-35-24)36-20-9-10-27(22(31)13-20)41-18-26-23(32)7-5-11-34-26/h5,7,9-11,13-15,17H,4,6,8,12,18H2,1-3H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461312 (US10774068, Example 17 | US11427560, Example 17) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C(F)(F)F)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H30ClF3N6O3/c1-4-43-28-15-24-21(14-25(28)40-29(42)8-6-12-41(2)3)30(19(16-36)17-38-24)39-20-9-10-27(23(32)13-20)44-18-26-22(31(33,34)35)7-5-11-37-26/h5,7,9-11,13-15,17H,4,6,8,12,18H2,1-3H3,(H,38,39)(H,40,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461314 (US10774068, Example 19 | US11427560, Example 19) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C#N)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H30ClN7O3/c1-4-41-29-15-25-23(14-26(29)38-30(40)8-6-12-39(2)3)31(21(17-34)18-36-25)37-22-9-10-28(24(32)13-22)42-19-27-20(16-33)7-5-11-35-27/h5,7,9-11,13-15,18H,4,6,8,12,19H2,1-3H3,(H,36,37)(H,38,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461317 (US10774068, Example 22 | US11427560, Example 22) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(F)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33FN6O3/c1-5-40-29-16-25-23(15-26(29)37-30(39)9-7-13-38(3)4)31(21(17-33)18-35-25)36-22-10-11-28(24(32)14-22)41-19-27-20(2)8-6-12-34-27/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461318 (US10774068, Example 23 | US11427560, Example 23) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3F)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33FN6O3/c1-5-40-29-16-26-23(15-27(29)36-30(39)9-7-13-38(3)4)31(21(17-33)18-35-26)37-25-11-10-22(14-24(25)32)41-19-28-20(2)8-6-12-34-28/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,37)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461319 (US10774068, Example 24 | US11427560, Example 24) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(Br)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33BrN6O3/c1-5-40-29-16-25-23(15-26(29)37-30(39)9-7-13-38(3)4)31(21(17-33)18-35-25)36-22-10-11-28(24(32)14-22)41-19-27-20(2)8-6-12-34-27/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461320 (US10774068, Example 25 | US11427560, Example 25) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3Cl)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H33ClN6O3/c1-5-40-29-16-26-23(15-27(29)36-30(39)9-7-13-38(3)4)31(21(17-33)18-35-26)37-25-11-10-22(14-24(25)32)41-19-28-20(2)8-6-12-34-28/h6,8,10-12,14-16,18H,5,7,9,13,19H2,1-4H3,(H,35,37)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461321 (US10774068, Example 26 | US11427560, Example 26) Show SMILES CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4ncccc4C)c(Cl)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C31H32Cl2N6O3/c1-5-41-28-15-25-22(14-26(28)38-29(40)9-7-11-39(3)4)30(20(16-34)17-36-25)37-21-12-23(32)31(24(33)13-21)42-18-27-19(2)8-6-10-35-27/h6,8,10,12-15,17H,5,7,9,11,18H2,1-4H3,(H,36,37)(H,38,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM461323 (US10774068, Example 28 | US11427560, Example 28) Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(OC)c3)c2cc1NC(=O)CCCN(C)C Show InChI InChI=1S/C32H36N6O4/c1-6-41-29-17-25-24(16-26(29)37-31(39)10-8-14-38(3)4)32(22(18-33)19-35-25)36-23-11-12-28(30(15-23)40-5)42-20-27-21(2)9-7-13-34-27/h7,9,11-13,15-17,19H,6,8,10,14,20H2,1-5H3,(H,35,36)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN US Patent					Assay Description MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...				US Patent US10774068 (2020) BindingDB Entry DOI: 10.7270/Q2S46W22
					More data for this Ligand-Target Pair

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