Compile Data Set for Download or QSAR

Found 4 hits of ic50 data for polymerid = 335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Rattus norvegicus (Rat))	BDBM24995 (2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-(piperi...) Show SMILES CCn1c(nc2cncc(C(=O)NC3CCNCC3)c12)-c1nonc1N Show InChI InChI=1S/C16H20N8O2/c1-2-24-13-10(16(25)20-9-3-5-18-6-4-9)7-19-8-11(13)21-15(24)12-14(17)23-26-22-12/h7-9,18H,2-6H2,1H3,(H2,17,23)(H,20,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Rattus norvegicus (Rat))	BDBM24996 (4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...) Show SMILES CCn1c(nc2cncc(CNC3CCNCC3)c12)-c1nonc1N Show InChI InChI=1S/C16H22N8O/c1-2-24-14-10(8-20-11-3-5-18-6-4-11)7-19-9-12(14)21-16(24)13-15(17)23-25-22-13/h7,9,11,18,20H,2-6,8H2,1H3,(H2,17,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Rattus norvegicus (Rat))	BDBM14027 (5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...) Show SMILES O=S(=O)(N1CCCNCC1)c1cccc2cnccc12 Show InChI InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	23
BIOAXONE BIOSCIENCES, INC. US Patent					Assay Description The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...				US Patent US9687483 (2017) BindingDB Entry DOI: 10.7270/Q2H993CZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Rho-associated protein kinase 1 (Rattus norvegicus (Rat))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	23
BIOAXONE BIOSCIENCES, INC. US Patent					Assay Description The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...				US Patent US9687483 (2017) BindingDB Entry DOI: 10.7270/Q2H993CZ
					More data for this Ligand-Target Pair