Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545128 (CHEMBL4641888) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50282224 (CHEMBL4172856) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes. | Eur J Med Chem 136: 283-293 (2017) Article DOI: 10.1016/j.ejmech.2017.04.067 BindingDB Entry DOI: 10.7270/Q29G5QB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50242188 (6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of SMS1 (unknown origin) | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182486 (MALABARICONE B) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182491 (CHEBI:69015 | Malabaricone C) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182487 (Malabaricone A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117841 (CHEMBL3613983) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545129 (CHEMBL4645607) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182491 (CHEBI:69015 | Malabaricone C) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545122 (CHEMBL4646354) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182486 (MALABARICONE B) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182487 (Malabaricone A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117832 (CHEMBL3613975) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117840 (CHEMBL3612087) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50182488 (CHEMBL3819036) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr... | ACS Med Chem Lett 10: 1154-1158 (2019) Article DOI: 10.1021/acsmedchemlett.9b00171 BindingDB Entry DOI: 10.7270/Q2WS8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117845 (CHEMBL3613987) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117842 (CHEMBL3613984) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117853 (CHEMBL3613995) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545126 (CHEMBL4646540) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117846 (CHEMBL3613988) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545121 (CHEMBL4638097) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545120 (CHEMBL4634697) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50282208 (CHEMBL4177314) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of full length C-terminal FLAG tagged human SMS1 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba... | Eur J Med Chem 136: 283-293 (2017) Article DOI: 10.1016/j.ejmech.2017.04.067 BindingDB Entry DOI: 10.7270/Q29G5QB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117848 (CHEMBL3613990) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117844 (CHEMBL3613986) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545114 (CHEMBL4644982) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545124 (CHEMBL4639746) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117843 (CHEMBL3613985) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545127 (CHEMBL4644293) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545123 (CHEMBL4638337) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545116 (CHEMBL4649105) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117839 (CHEMBL3613982) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545119 (CHEMBL4634669) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458937 (CHEMBL4217275) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458939 (CHEMBL4202436) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458926 (CHEMBL4211357) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117836 (CHEMBL3613979) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117838 (CHEMBL3613981) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117847 (CHEMBL3613989) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458921 (CHEMBL4204352) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458919 (CHEMBL4207944) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458938 (CHEMBL4203399) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458932 (CHEMBL4217676) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458942 (CHEMBL4202973) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50458927 (CHEMBL4214637) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min... | J Med Chem 61: 8241-8254 (2018) Article DOI: 10.1021/acs.jmedchem.8b00727 BindingDB Entry DOI: 10.7270/Q2W37ZZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50282209 (CHEMBL1161894) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against human Dihydrofolate reductase | Eur J Med Chem 136: 283-293 (2017) Article DOI: 10.1016/j.ejmech.2017.04.067 BindingDB Entry DOI: 10.7270/Q29G5QB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117849 (CHEMBL3613991) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50117850 (CHEMBL3613992) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL... | Bioorg Med Chem 23: 6173-84 (2015) Article DOI: 10.1016/j.bmc.2015.07.060 BindingDB Entry DOI: 10.7270/Q2NG4SF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545118 (CHEMBL4637599) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (Homo sapiens (Human)) | BDBM50545117 (CHEMBL4647686) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115376 BindingDB Entry DOI: 10.7270/Q2J106QT | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 64 total ) | Next | Last >> |