BindingDB PrimarySearch

Found 240 hits of ic50 data for polymerid = 547,5715
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Smooth muscle myosin light chain kinase of chicken gizzard				J Med Chem 40: 1863-9 (1997) Article DOI: 10.1021/jm970031d BindingDB Entry DOI: 10.7270/Q2W95891
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50058332 (CHEMBL299496 \| methyl 10,23-di(ethylsulfanylmethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Smooth muscle myosin light chain kinase of chicken gizzard				J Med Chem 40: 1863-9 (1997) Article DOI: 10.1021/jm970031d BindingDB Entry DOI: 10.7270/Q2W95891
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against myosin light-chain kinase from chicken gizzard (M-kinase)				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM199250 (US9221808, 1bo \| US9221808, 1bo-HCl \| US9221808, 1...) Show SMILES Oc1cccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Moffitt Cancer Center Curated by ChEMBL					Assay Description Inhibition of MLCK1 (unknown origin)				Medchemcomm 3: 699-709 (2012) Article DOI: 10.1039/c2md00320a BindingDB Entry DOI: 10.7270/Q2571G0R
Moffitt Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3040 (23-(3-aminopropyl)-3-methyl-3,13,23-triazahexacycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3040 (23-(3-aminopropyl)-3-methyl-3,13,23-triazahexacycl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Myosin light chain kinase 1 (MLCK1)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50118955 (CHEMBL94678 \| Compound K-252a(epi)) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Myosin light chain kinase 1 (MLCK1)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3035 (3-{7,19-dihydroxy-23-methyl-14-oxo-3,13,23-triazah...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3035 (3-{7,19-dihydroxy-23-methyl-14-oxo-3,13,23-triazah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3038 (23-[3-(dimethylamino)propyl]-7,19-dihydroxy-3,13,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	31	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3047 (4-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50284317 (3-(9-methoxy-13-methyl-5,7-dioxo-6,7,12,13-tetrahy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074653 (CHEMBL385812 \| R-K-K-Y-(Ach)-Y-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	43.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MLCK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
TBA					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3044 (3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	49	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074638 (CHEMBL443574 \| R-K-K-Y-K-Y-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	51.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human MLCK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
University of Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3043 (3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	55	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3043 (3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50280875 (3-(5-oxo-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against myosin light-chain kinase from chicken gizzard (M-kinase)				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074648 (CHEMBL268790 \| R-K-K-Y-(Ach)-(Ach)-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50284318 (13-(3-dimethylamino-2-hydroxypropyl)-3-methoxy-12-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074635 (CHEMBL425624 \| R-K-K-Y-K-P-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3048 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3048 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3049 (23-[3-(dimethylamino)-2-hydroxypropyl]-7-methoxy-3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074644 (CHEMBL409544 \| R-K-K-Y-K-F-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074657 (CHEMBL267348 \| R-K-K-Y-K-S-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074637 (CHEMBL265891 \| R-K-K-Y-K-M-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074642 (CHEMBL262895 \| R-K-K-Y-K-I-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Inhibition of MLCK by HTRF assay				Bioorg Med Chem 19: 429-39 (2011) Article DOI: 10.1016/j.bmc.2010.11.007 BindingDB Entry DOI: 10.7270/Q22F7NQN
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3046 (3-{7,19-dimethoxy-23-methyl-12,14-dioxo-3,13,23-tr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3046 (3-{7,19-dimethoxy-23-methyl-12,14-dioxo-3,13,23-tr...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074639 (CHEMBL404932 \| R-K-K-Y-K-W-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3044 (3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazah...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074652 (CHEMBL216528 \| R-K-K-Y-K-K-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3037 (23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3037 (23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3039 (23-[3-(dimethylamino)propyl]-3-methyl-3,13,23-tria...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3039 (23-[3-(dimethylamino)propyl]-3-methyl-3,13,23-tria...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
Tumor Biology Center					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of chicken SmMLCK expressed in Escherichia coli				Biochem J 351: 95-105 (2001) BindingDB Entry DOI: 10.7270/Q24T6JKN
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50590939 (CHEMBL5174830) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
TBA					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074646 (CHEMBL415435 \| R-K-K-Y-K-(Ach)-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074645 (CHEMBL265875 \| R-K-K-Y-K-H-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50074649 (CHEMBL262286 \| R-K-K-Y-K-N-R-R-K-NH2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)				J Med Chem 42: 910-9 (1999) Article DOI: 10.1021/jm980573a BindingDB Entry DOI: 10.7270/Q2JS9R4T
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair

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