Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50318494 (3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50227245 (CHEMBL3392281) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035794 (4-Methyl-2-methylsulfanyl-13-nitro-3,8,9,10,11,16b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50226760 (CHEMBL2398396) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035795 (4-Methyl-2-methylsulfanyl-3,8,9,10,11,16b-hexahydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035800 ((S)-2,6-Dimethyl-5-nitro-4-(2-trifluoromethyl-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50015432 (6-Methyl-2-methylsulfanyl-4-(3-nitro-phenyl)-1,4-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035790 (6-Methyl-2-methylsulfanyl-4-(2-methylsulfanyl-3-ni...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50226761 (CHEMBL3392285) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50226804 (CHEMBL88149) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50226978 (CHEMBL282279) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50016385 (4-Methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]-nitrendipine binding to calcium channels of guinea pig myocardium | J Med Chem 30: 635-40 (1987) BindingDB Entry DOI: 10.7270/Q25B01G9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035789 (6-Methyl-2-methylsulfanyl-4-(3-nitro-phenyl)-1,4-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50016388 (5-(2-Dimethylamino-ethyl)-4-methyl-2-(3-nitro-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 488 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]-nitrendipine binding to calcium channels of guinea pig myocardium | J Med Chem 30: 635-40 (1987) BindingDB Entry DOI: 10.7270/Q25B01G9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035797 (4-Methyl-2-methylsulfanyl-15-nitro-3,8,9,10,11,16b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 873 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035793 (6-Methyl-2-methylsulfanyl-4-(2-methylsulfanyl-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035802 (6-Methyl-2-methylsulfanyl-4-(2-methylsulfanyl-5-ni...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50226808 (CHEMBL3392278) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes | J Med Chem 33: 1510-5 (1990) BindingDB Entry DOI: 10.7270/Q2MW2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035799 (2-Methylsulfanyl-4-(2-methylsulfanyl-3-nitro-pheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.37E+4 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035796 (2-Methylsulfanyl-4-(3-nitro-phenyl)-4,7-dihydro-1H...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.69E+4 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035791 (2-Methylsulfanyl-4-(2-methylsulfanyl-phenyl)-4,7-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035801 (2-Methylsulfanyl-4-(2-methylsulfanyl-5-nitro-pheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50035798 (4-(2-Butylsulfanyl-phenyl)-2-methylsulfanyl-4,7-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes | J Med Chem 38: 119-29 (1995) BindingDB Entry DOI: 10.7270/Q2F76D7F | |||||||||||
More data for this Ligand-Target Pair |