BindingDB logo
myBDB logout

PubMed code 10206558

Compile data set for download or QSAR
Found 50 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076091
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CC[C@H]3CCC[C@H](C)N3C)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h14-21H,4-13H2,1-3H3/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 4.30n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076089
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12
Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 4.5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076090
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(octahydro-q...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC4CCCCC34)[C@@H]12
Show InChI InChI=1S/C25H41NO2/c1-17-24-21(20-11-4-2-9-19(20)16-22(24)25(27)28-17)12-7-15-26-14-6-10-18-8-3-5-13-23(18)26/h17-24H,2-16H2,1H3/t17-,18?,19+,20-,21+,22-,23?,24+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 13n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076088
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(Adamantan-1-ylamino)...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCNC34CC5CC(CC(C5)C3)C4)[C@@H]12 |TLB:25:20:27:24.26.23,25:24:27:20.19.21,THB:23:24:19:22.27.21,23:22:19:24.26.25|
Show InChI InChI=1S/C26H41NO2/c1-16-24-22(21-6-3-2-5-20(21)12-23(24)25(28)29-16)7-4-8-27-26-13-17-9-18(14-26)11-19(10-17)15-26/h16-24,27H,2-15H2,1H3/t16-,17?,18?,19?,20+,21-,22+,23-,24+,26?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 26n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076091
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CC[C@H]3CCC[C@H](C)N3C)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h14-21H,4-13H2,1-3H3/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 32n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076090
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(octahydro-q...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC4CCCCC34)[C@@H]12
Show InChI InChI=1S/C25H41NO2/c1-17-24-21(20-11-4-2-9-19(20)16-22(24)25(27)28-17)12-7-15-26-14-6-10-18-8-3-5-13-23(18)26/h17-24H,2-16H2,1H3/t17-,18?,19+,20-,21+,22-,23?,24+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 38n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076092
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-piperazin-1-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCNCC3)[C@@H]12
Show InChI InChI=1S/C20H34N2O2/c1-14-19-17(7-4-10-22-11-8-21-9-12-22)16-6-3-2-5-15(16)13-18(19)20(23)24-14/h14-19,21H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>42n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076089
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12
Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 48n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076077
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-morpholin-4-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCOCC3)[C@@H]12
Show InChI InChI=1S/C20H33NO3/c1-14-19-17(7-4-8-21-9-11-23-12-10-21)16-6-3-2-5-15(16)13-18(19)20(22)24-14/h14-19H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 51n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076088
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(Adamantan-1-ylamino)...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCNC34CC5CC(CC(C5)C3)C4)[C@@H]12 |TLB:25:20:27:24.26.23,25:24:27:20.19.21,THB:23:24:19:22.27.21,23:22:19:24.26.25|
Show InChI InChI=1S/C26H41NO2/c1-16-24-22(21-6-3-2-5-20(21)12-23(24)25(28)29-16)7-4-8-27-26-13-17-9-18(14-26)11-19(10-17)15-26/h16-24,27H,2-15H2,1H3/t16-,17?,18?,19?,20+,21-,22+,23-,24+,26?/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 136n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076080
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3-Hydroxy-piperidin-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(O)C3)[C@@H]12
Show InChI InChI=1S/C21H35NO3/c1-14-20-18(9-5-11-22-10-4-7-16(23)13-22)17-8-3-2-6-15(17)12-19(20)21(24)25-14/h14-20,23H,2-13H2,1H3/t14-,15+,16?,17-,18+,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 148n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076076
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-thiomorpholi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCSCC3)[C@@H]12
Show InChI InChI=1S/C20H33NO2S/c1-14-19-17(7-4-8-21-9-11-24-12-10-21)16-6-3-2-5-15(16)13-18(19)20(22)23-14/h14-19H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 179n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076086
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,4-Dihydro-1H-isoqu...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCc4ccccc4C3)[C@@H]12
Show InChI InChI=1S/C25H35NO2/c1-17-24-22(21-10-5-4-8-19(21)15-23(24)25(27)28-17)11-6-13-26-14-12-18-7-2-3-9-20(18)16-26/h2-3,7,9,17,19,21-24H,4-6,8,10-16H2,1H3/t17-,19+,21-,22+,23-,24+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 184n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076076
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-thiomorpholi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCSCC3)[C@@H]12
Show InChI InChI=1S/C20H33NO2S/c1-14-19-17(7-4-8-21-9-11-24-12-10-21)16-6-3-2-5-15(16)13-18(19)20(22)23-14/h14-19H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 189n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076083
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2-Ethyl-piperidin-1-...)
Show SMILES CCC1CCCCN1CCC[C@H]1[C@H]2[C@H](C)OC(=O)[C@H]2C[C@H]2CCCC[C@H]12
Show InChI InChI=1S/C23H39NO2/c1-3-18-10-6-7-13-24(18)14-8-12-20-19-11-5-4-9-17(19)15-21-22(20)16(2)26-23(21)25/h16-22H,3-15H2,1-2H3/t16-,17+,18?,19-,20+,21-,22+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 209n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076077
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-morpholin-4-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCOCC3)[C@@H]12
Show InChI InChI=1S/C20H33NO3/c1-14-19-17(7-4-8-21-9-11-23-12-10-21)16-6-3-2-5-15(16)13-18(19)20(22)24-14/h14-19H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 222n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076084
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,3-Dimethyl-piperid...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(C)(C)C3)[C@@H]12
Show InChI InChI=1S/C23H39NO2/c1-16-21-19(10-6-12-24-13-7-11-23(2,3)15-24)18-9-5-4-8-17(18)14-20(21)22(25)26-16/h16-21H,4-15H2,1-3H3/t16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 224n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076075
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(2-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCCC3C)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-8-5-6-12-23(15)13-7-11-19-18-10-4-3-9-17(18)14-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 275n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076097
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(4-Hydroxy-piperidin-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(O)CC3)[C@@H]12
Show InChI InChI=1S/C21H35NO3/c1-14-20-18(7-4-10-22-11-8-16(23)9-12-22)17-6-3-2-5-15(17)13-19(20)21(24)25-14/h14-20,23H,2-13H2,1H3/t14-,15+,17-,18+,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>280n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076094
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(4-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(C)CC3)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-9-12-23(13-10-15)11-5-8-19-18-7-4-3-6-17(18)14-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 283n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076086
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,4-Dihydro-1H-isoqu...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCc4ccccc4C3)[C@@H]12
Show InChI InChI=1S/C25H35NO2/c1-17-24-22(21-10-5-4-8-19(21)15-23(24)25(27)28-17)11-6-13-26-14-12-18-7-2-3-9-20(18)16-26/h2-3,7,9,17,19,21-24H,4-6,8,10-16H2,1H3/t17-,19+,21-,22+,23-,24+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 304n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076093
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-(3-[1,4']Bipiperidinyl-1...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(CC3)N3CCCCC3)[C@@H]12
Show InChI InChI=1S/C26H44N2O2/c1-19-25-23(22-9-4-3-8-20(22)18-24(25)26(29)30-19)10-7-13-27-16-11-21(12-17-27)28-14-5-2-6-15-28/h19-25H,2-18H2,1H3/t19-,20+,22-,23+,24-,25+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 312n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076082
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(3-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-7-5-11-23(14-15)12-6-10-19-18-9-4-3-8-17(18)13-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 312n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076083
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2-Ethyl-piperidin-1-...)
Show SMILES CCC1CCCCN1CCC[C@H]1[C@H]2[C@H](C)OC(=O)[C@H]2C[C@H]2CCCC[C@H]12
Show InChI InChI=1S/C23H39NO2/c1-3-18-10-6-7-13-24(18)14-8-12-20-19-11-5-4-9-17(19)15-21-22(20)16(2)26-23(21)25/h16-22H,3-15H2,1-2H3/t16-,17+,18?,19-,20+,21-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 341n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076096
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-piperidin-1-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCCC3)[C@@H]12
Show InChI InChI=1S/C21H35NO2/c1-15-20-18(10-7-13-22-11-5-2-6-12-22)17-9-4-3-8-16(17)14-19(20)21(23)24-15/h15-20H,2-14H2,1H3/t15-,16+,17-,18+,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 352n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076079
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2,5-Dimethyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)NCC3C)[C@@H]12
Show InChI InChI=1S/C22H38N2O2/c1-14-13-24(15(2)12-23-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)25/h14-21,23H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 353n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076087
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2,6-Dimethyl-morphol...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)OC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H37NO3/c1-14-12-23(13-15(2)25-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)24/h14-21H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 376n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076082
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(3-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-7-5-11-23(14-15)12-6-10-19-18-9-4-3-8-17(18)13-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t15?,16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 376n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076075
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(2-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCCC3C)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-8-5-6-12-23(15)13-7-11-19-18-10-4-3-9-17(18)14-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t15?,16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 399n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076084
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,3-Dimethyl-piperid...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(C)(C)C3)[C@@H]12
Show InChI InChI=1S/C23H39NO2/c1-16-21-19(10-6-12-24-13-7-11-23(2,3)15-24)18-9-5-4-8-17(18)14-20(21)22(25)26-16/h16-21H,4-15H2,1-3H3/t16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 416n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076092
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-piperazin-1-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCNCC3)[C@@H]12
Show InChI InChI=1S/C20H34N2O2/c1-14-19-17(7-4-10-22-11-8-21-9-12-22)16-6-3-2-5-15(16)13-18(19)20(23)24-14/h14-19,21H,2-13H2,1H3/t14-,15+,16-,17+,18-,19+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>420n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076096
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-(3-piperidin-1-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCCC3)[C@@H]12
Show InChI InChI=1S/C21H35NO2/c1-15-20-18(10-7-13-22-11-5-2-6-12-22)17-9-4-3-8-16(17)14-19(20)21(23)24-15/h15-20H,2-14H2,1H3/t15-,16+,17-,18+,19-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 427n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076095
PNG
(4-[3-((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-1-oxo-dodec...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(CC3)C(=O)OC(C)(C)C)[C@@H]12
Show InChI InChI=1S/C25H42N2O4/c1-17-22-20(19-9-6-5-8-18(19)16-21(22)23(28)30-17)10-7-11-26-12-14-27(15-13-26)24(29)31-25(2,3)4/h17-22H,5-16H2,1-4H3/t17-,18+,19-,20+,21-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 445n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076098
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(4-Cyclohexyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(CC3)C3CCCCC3)[C@@H]12
Show InChI InChI=1S/C26H44N2O2/c1-19-25-23(22-11-6-5-8-20(22)18-24(25)26(29)30-19)12-7-13-27-14-16-28(17-15-27)21-9-3-2-4-10-21/h19-25H,2-18H2,1H3/t19-,20+,22-,23+,24-,25+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 464n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076095
PNG
(4-[3-((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-1-oxo-dodec...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(CC3)C(=O)OC(C)(C)C)[C@@H]12
Show InChI InChI=1S/C25H42N2O4/c1-17-22-20(19-9-6-5-8-18(19)16-21(22)23(28)30-17)10-7-11-26-12-14-27(15-13-26)24(29)31-25(2,3)4/h17-22H,5-16H2,1-4H3/t17-,18+,19-,20+,21-,22+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 485n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076078
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,5-Dimethyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)NC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H38N2O2/c1-14-12-24(13-15(2)23-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)25/h14-21,23H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>500n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076081
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-((S)-3-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN[C@@H](C)C3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-14-13-23(11-9-22-14)10-5-8-18-17-7-4-3-6-16(17)12-19-20(18)15(2)25-21(19)24/h14-20,22H,3-13H2,1-2H3/t14-,15-,16+,17-,18+,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>500n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076099
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-((R)-3-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN[C@H](C)C3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-14-13-23(11-9-22-14)10-5-8-18-17-7-4-3-6-16(17)12-19-20(18)15(2)25-21(19)24/h14-20,22H,3-13H2,1-2H3/t14-,15+,16-,17+,18-,19+,20-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>500n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076098
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(4-Cyclohexyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(CC3)C3CCCCC3)[C@@H]12
Show InChI InChI=1S/C26H44N2O2/c1-19-25-23(22-11-6-5-8-20(22)18-24(25)26(29)30-19)12-7-13-27-14-16-28(17-15-27)21-9-3-2-4-10-21/h19-25H,2-18H2,1H3/t19-,20+,22-,23+,24-,25+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 520n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076094
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(4-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(C)CC3)[C@@H]12
Show InChI InChI=1S/C22H37NO2/c1-15-9-12-23(13-10-15)11-5-8-19-18-7-4-3-6-17(18)14-20-21(19)16(2)25-22(20)24/h15-21H,3-14H2,1-2H3/t16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 554n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076079
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2,5-Dimethyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)NCC3C)[C@@H]12
Show InChI InChI=1S/C22H38N2O2/c1-14-13-24(15(2)12-23-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)25/h14-21,23H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 570n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076085
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(4-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(C)CC3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-15-20-18(8-5-9-23-12-10-22(2)11-13-23)17-7-4-3-6-16(17)14-19(20)21(24)25-15/h15-20H,3-14H2,1-2H3/t15-,16+,17-,18+,19-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 579n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076081
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-((S)-3-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN[C@@H](C)C3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-14-13-23(11-9-22-14)10-5-8-18-17-7-4-3-6-16(17)12-19-20(18)15(2)25-21(19)24/h14-20,22H,3-13H2,1-2H3/t14-,15-,16+,17-,18+,19-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 581n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076085
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-(4-methyl-pi...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN(C)CC3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-15-20-18(8-5-9-23-12-10-22(2)11-13-23)17-7-4-3-6-16(17)14-19(20)21(24)25-15/h15-20H,3-14H2,1-2H3/t15-,16+,17-,18+,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 595n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076087
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(2,6-Dimethyl-morphol...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)OC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H37NO3/c1-14-12-23(13-15(2)25-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)24/h14-21H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 601n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50076093
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-(3-[1,4']Bipiperidinyl-1...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(CC3)N3CCCCC3)[C@@H]12
Show InChI InChI=1S/C26H44N2O2/c1-19-25-23(22-9-4-3-8-20(22)18-24(25)26(29)30-19)10-7-13-27-16-11-21(12-17-27)28-14-5-2-6-15-28/h19-25H,2-18H2,1H3/t19-,20+,22-,23+,24-,25+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 650n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076099
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[3-((R)-3-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCN[C@H](C)C3)[C@@H]12
Show InChI InChI=1S/C21H36N2O2/c1-14-13-23(11-9-22-14)10-5-8-18-17-7-4-3-6-16(17)12-19-20(18)15(2)25-21(19)24/h14-20,22H,3-13H2,1-2H3/t14-,15+,16-,17+,18-,19+,20-/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 857n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076097
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(4-Hydroxy-piperidin-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCC(O)CC3)[C@@H]12
Show InChI InChI=1S/C21H35NO3/c1-14-20-18(7-4-10-22-11-8-16(23)9-12-22)17-6-3-2-5-15(17)13-19(20)21(24)25-14/h14-20,23H,2-13H2,1H3/t14-,15+,17-,18+,19-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>900n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076078
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3,5-Dimethyl-piperaz...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CC(C)NC(C)C3)[C@@H]12
Show InChI InChI=1S/C22H38N2O2/c1-14-12-24(13-15(2)23-14)10-6-9-19-18-8-5-4-7-17(18)11-20-21(19)16(3)26-22(20)25/h14-21,23H,4-13H2,1-3H3/t14?,15?,16-,17+,18-,19+,20-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 1.36E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50076080
PNG
((3S,3aR,4R,4aS,8aR,9aS)-4-[3-(3-Hydroxy-piperidin-...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](CCCN3CCCC(O)C3)[C@@H]12
Show InChI InChI=1S/C21H35NO3/c1-14-20-18(9-5-11-22-10-4-7-16(23)13-22)17-8-3-2-6-15(17)12-19(20)21(24)25-14/h14-20,23H,2-13H2,1H3/t14-,15+,16?,17-,18+,19-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 1.53E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligand

Bioorg Med Chem Lett 9: 901-6 (1999)


BindingDB Entry DOI: 10.7270/Q2J102CP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%