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PubMed code 10346928

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077198
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-{(S)-2-(2-naph...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)Cc2cccc3ccccc23)cc1
Show InChI InChI=1S/C36H36N4O9/c1-49-27-15-11-23(12-16-27)21-37-33(44)29(17-18-32(42)43)40-34(45)30(19-22-9-13-26(14-10-22)38-35(46)36(47)48)39-31(41)20-25-7-4-6-24-5-2-3-8-28(24)25/h2-16,29-30H,17-21H2,1H3,(H,37,44)(H,38,46)(H,39,41)(H,40,45)(H,42,43)(H,47,48)/t29-,30-/m0/s1
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n/an/an/a 3.00E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077210
PNG
((S)-4-{(S)-2-Acetylamino-3-[4-(2-carboxy-ethyl)-ph...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(CCC(O)=O)cc2)NC(C)=O)cc1
Show InChI InChI=1S/C27H33N3O8/c1-17(31)29-23(15-19-5-3-18(4-6-19)9-13-24(32)33)27(37)30-22(12-14-25(34)35)26(36)28-16-20-7-10-21(38-2)11-8-20/h3-8,10-11,22-23H,9,12-16H2,1-2H3,(H,28,36)(H,29,31)(H,30,37)(H,32,33)(H,34,35)/t22-,23-/m0/s1
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n/an/an/a 1.84E+5n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077199
PNG
((S)-4-{(S)-2-Acetylamino-3-[4-(oxalyl-amino)-pheny...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(C)=O)cc1
Show InChI InChI=1S/C26H30N4O9/c1-15(31)28-21(13-16-3-7-18(8-4-16)29-25(36)26(37)38)24(35)30-20(11-12-22(32)33)23(34)27-14-17-5-9-19(39-2)10-6-17/h3-10,20-21H,11-14H2,1-2H3,(H,27,34)(H,28,31)(H,29,36)(H,30,35)(H,32,33)(H,37,38)/t20-,21-/m0/s1
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n/an/an/a 4.20E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077204
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-[(S)-2-(2-naph...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(CS(O)(=O)=O)cc2)NC(=O)Cc2cccc3ccccc23)cc1
Show InChI InChI=1S/C35H37N3O9S/c1-47-28-15-13-24(14-16-28)21-36-34(42)30(17-18-33(40)41)38-35(43)31(19-23-9-11-25(12-10-23)22-48(44,45)46)37-32(39)20-27-7-4-6-26-5-2-3-8-29(26)27/h2-16,30-31H,17-22H2,1H3,(H,36,42)(H,37,39)(H,38,43)(H,40,41)(H,44,45,46)/t30-,31-/m0/s1
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n/an/an/a 4.00E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077209
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-[(S)-3-[4-(oxa...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)CCc2ccccc2)cc1
Show InChI InChI=1S/C33H36N4O9/c1-46-25-14-9-23(10-15-25)20-34-30(41)26(16-18-29(39)40)37-31(42)27(36-28(38)17-11-21-5-3-2-4-6-21)19-22-7-12-24(13-8-22)35-32(43)33(44)45/h2-10,12-15,26-27H,11,16-20H2,1H3,(H,34,41)(H,35,43)(H,36,38)(H,37,42)(H,39,40)(H,44,45)/t26-,27-/m0/s1
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n/an/an/a 1.30E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077200
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-carboxymethyl-phenyl...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(CC(O)=O)cc2)NC(C)=O)cc1
Show InChI InChI=1S/C26H31N3O8/c1-16(30)28-22(13-17-3-5-18(6-4-17)14-24(33)34)26(36)29-21(11-12-23(31)32)25(35)27-15-19-7-9-20(37-2)10-8-19/h3-10,21-22H,11-15H2,1-2H3,(H,27,35)(H,28,30)(H,29,36)(H,31,32)(H,33,34)/t21-,22-/m0/s1
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n/an/an/a 5.00E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077203
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-{(S)-2-(2-naph...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)Cc2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C36H36N4O9/c1-49-28-14-9-23(10-15-28)21-37-33(44)29(16-17-32(42)43)40-34(45)30(19-22-7-12-27(13-8-22)38-35(46)36(47)48)39-31(41)20-24-6-11-25-4-2-3-5-26(25)18-24/h2-15,18,29-30H,16-17,19-21H2,1H3,(H,37,44)(H,38,46)(H,39,41)(H,40,45)(H,42,43)(H,47,48)/t29-,30-/m0/s1
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n/an/an/a 3.00E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077207
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-{(S)-3-[4-(oxa...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)Cc2ccccc2)cc1
Show InChI InChI=1S/C32H34N4O9/c1-45-24-13-9-22(10-14-24)19-33-29(40)25(15-16-28(38)39)36-30(41)26(35-27(37)18-20-5-3-2-4-6-20)17-21-7-11-23(12-8-21)34-31(42)32(43)44/h2-14,25-26H,15-19H2,1H3,(H,33,40)(H,34,42)(H,35,37)(H,36,41)(H,38,39)(H,43,44)/t25-,26-/m0/s1
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n/an/an/a 1.70E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077208
PNG
((S)-4-(4-Methoxy-benzylcarbamoyl)-4-[(S)-2-(2-naph...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)Cc2cccc3ccccc23)cc1
Show InChI InChI=1S/C34H36N3O10P/c1-46-26-13-11-23(12-14-26)21-35-33(41)29(17-18-32(39)40)37-34(42)30(19-22-9-15-27(16-10-22)47-48(43,44)45)36-31(38)20-25-7-4-6-24-5-2-3-8-28(24)25/h2-16,29-30H,17-21H2,1H3,(H,35,41)(H,36,38)(H,37,42)(H,39,40)(H2,43,44,45)/t29-,30-/m0/s1
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n/an/an/a 40n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077197
PNG
((S)-4-[(S)-3-[4-(Carboxy-hydroxy-methyl)-phenyl]-2...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(cc2)C(O)C(O)=O)NC(=O)Cc2cccc3ccccc23)cc1
Show InChI InChI=1S/C36H37N3O9/c1-48-27-15-11-23(12-16-27)21-37-34(44)29(17-18-32(41)42)39-35(45)30(19-22-9-13-25(14-10-22)33(43)36(46)47)38-31(40)20-26-7-4-6-24-5-2-3-8-28(24)26/h2-16,29-30,33,43H,17-21H2,1H3,(H,37,44)(H,38,40)(H,39,45)(H,41,42)(H,46,47)/t29-,30-,33?/m0/s1
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n/an/an/a 2.00E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50369429
PNG
(CHEMBL1790311)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(CC(O)=O)cc1)NC(C)=O)C(O)=O
Show InChI InChI=1S/C29H40N4O12/c1-4-15(2)25(29(44)45)33-27(42)20(10-12-23(37)38)31-26(41)19(9-11-22(35)36)32-28(43)21(30-16(3)34)13-17-5-7-18(8-6-17)14-24(39)40/h5-8,15,19-21,25H,4,9-14H2,1-3H3,(H,30,34)(H,31,41)(H,32,43)(H,33,42)(H,35,36)(H,37,38)(H,39,40)(H,44,45)/t15-,19-,20-,21-,25-/m0/s1
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n/an/an/a 4.20E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077212
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-sulfomethyl-phenyl)-...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(CS(O)(=O)=O)cc2)NC(C)=O)cc1
Show InChI InChI=1S/C25H31N3O9S/c1-16(29)27-22(13-17-3-5-19(6-4-17)15-38(34,35)36)25(33)28-21(11-12-23(30)31)24(32)26-14-18-7-9-20(37-2)10-8-18/h3-10,21-22H,11-15H2,1-2H3,(H,26,32)(H,27,29)(H,28,33)(H,30,31)(H,34,35,36)/t21-,22-/m0/s1
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n/an/an/a 2.50E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077196
PNG
((S)-4-{(S)-2-Benzoylamino-3-[4-(oxalyl-amino)-phen...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C31H32N4O9/c1-44-23-13-9-20(10-14-23)18-32-28(39)24(15-16-26(36)37)34-29(40)25(35-27(38)21-5-3-2-4-6-21)17-19-7-11-22(12-8-19)33-30(41)31(42)43/h2-14,24-25H,15-18H2,1H3,(H,32,39)(H,33,41)(H,34,40)(H,35,38)(H,36,37)(H,42,43)/t24-,25-/m0/s1
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n/an/an/a 3.20E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074261
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(C)=O)cc1
Show InChI InChI=1S/C24H30N3O10P/c1-15(28)26-21(13-16-3-9-19(10-4-16)37-38(33,34)35)24(32)27-20(11-12-22(29)30)23(31)25-14-17-5-7-18(36-2)8-6-17/h3-10,20-21H,11-14H2,1-2H3,(H,25,31)(H,26,28)(H,27,32)(H,29,30)(H2,33,34,35)/t20-,21-/m0/s1
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n/an/an/a 200n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077202
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-oxalyl-phenyl)-propi...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(cc2)C(=O)C(O)=O)NC(C)=O)cc1
Show InChI InChI=1S/C26H29N3O9/c1-15(30)28-21(13-16-3-7-18(8-4-16)23(33)26(36)37)25(35)29-20(11-12-22(31)32)24(34)27-14-17-5-9-19(38-2)10-6-17/h3-10,20-21H,11-14H2,1-2H3,(H,27,34)(H,28,30)(H,29,35)(H,31,32)(H,36,37)/t20-,21-/m0/s1
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n/an/an/a 6.50E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077201
PNG
((S)-4-{(S)-2-Acetylamino-3-[4-(carboxy-hydroxy-met...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(cc2)C(O)C(O)=O)NC(C)=O)cc1
Show InChI InChI=1S/C26H31N3O9/c1-15(30)28-21(13-16-3-7-18(8-4-16)23(33)26(36)37)25(35)29-20(11-12-22(31)32)24(34)27-14-17-5-9-19(38-2)10-6-17/h3-10,20-21,23,33H,11-14H2,1-2H3,(H,27,34)(H,28,30)(H,29,35)(H,31,32)(H,36,37)/t20-,21-,23?/m0/s1
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n/an/an/a 1.50E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074242
PNG
((2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-ph...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O
Show InChI InChI=1S/C27H39N4O14P/c1-4-14(2)23(27(40)41)31-25(38)19(10-12-22(35)36)29-24(37)18(9-11-21(33)34)30-26(39)20(28-15(3)32)13-16-5-7-17(8-6-16)45-46(42,43)44/h5-8,14,18-20,23H,4,9-13H2,1-3H3,(H,28,32)(H,29,37)(H,30,39)(H,31,38)(H,33,34)(H,35,36)(H,40,41)(H2,42,43,44)/t14-,18-,19-,20-,23-/m0/s1
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n/an/an/a 100n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077211
PNG
((S)-4-[(S)-3-(4-Carboxymethyl-phenyl)-2-(2-naphtha...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(CC(O)=O)cc2)NC(=O)Cc2cccc3ccccc23)cc1
Show InChI InChI=1S/C36H37N3O8/c1-47-28-15-13-25(14-16-28)22-37-35(45)30(17-18-33(41)42)39-36(46)31(19-23-9-11-24(12-10-23)20-34(43)44)38-32(40)21-27-7-4-6-26-5-2-3-8-29(26)27/h2-16,30-31H,17-22H2,1H3,(H,37,45)(H,38,40)(H,39,46)(H,41,42)(H,43,44)/t30-,31-/m0/s1
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n/an/an/a 5.00E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50077205
PNG
((S)-4-{(S)-2-Acetylamino-3-[4-(carboxy-difluoro-me...)
Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(cc2)C(F)(F)C(O)=O)NC(C)=O)cc1
Show InChI InChI=1S/C26H29F2N3O8/c1-15(32)30-21(13-16-3-7-18(8-4-16)26(27,28)25(37)38)24(36)31-20(11-12-22(33)34)23(35)29-14-17-5-9-19(39-2)10-6-17/h3-10,20-21H,11-14H2,1-2H3,(H,29,35)(H,30,32)(H,31,36)(H,33,34)(H,37,38)/t20-,21-/m0/s1
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n/an/an/a 1.66E+5n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay

J Med Chem 42: 1757-66 (1999)


Article DOI: 10.1021/jm980676t
BindingDB Entry DOI: 10.7270/Q29P32BR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%