Affinity Data by PubMed id=10354398

PubMed code 10354398

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50077360 (3,10-Dihydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077357 (14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077362 (14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077357 (14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077358 (3-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077361 (3-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077360 (3,10-Dihydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077361 (3-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077359 (7-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of HIV-1 replication				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077358 (3-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077362 (14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50077359 (7-Hydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,9,10,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity agaginst integrase as yield of terminal cleavage products				J Med Chem 42: 1901-7 (1999) Article DOI: 10.1021/jm9806650 BindingDB Entry DOI: 10.7270/Q2PG1QWC
Institute of Chemical Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%