Affinity Data by PubMed id=11052791

PubMed code 11052791

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50092658 (4-Methyl-benzo[b]thiophene-2-carboxamidine(B428) \|...) Show SMILES Cc1cccc2sc(cc12)C(N)=N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine \| 4-aminobenzamidine \| CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM16173 (3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50092659 (2-AMINO-5-HYDROXY-BENZIMIDAZOLE \| 2-Amino-3H-benzo...) Show SMILES Nc1nc2ccc(O)cc2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents	MMDB PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50053620 (1-phenylguanidine \| 1N-amino(immino)methylaniline ...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM7960 (1H-1,3-benzodiazol-2-amine \| 2-Aminobenzimidazole ...) Show SMILES Nc1nc2ccccc2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%