Affinity Data by PubMed id=11294380

PubMed code 11294380

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50005480 ((-)-combretastatin \| (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50006677 (1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098052 (3,4,5-Trimethoxy-benzenesulfonic acid 1-methyl-1H-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50009565 (CHEMBL312992 \| Dimethyl-{4-[(Z)-2-(3,4,5-trimethox...) Show SMILES COc1cc(\C=C/c2ccc(cc2)N(C)C)cc(OC)c1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098051 (3,4,5-Trimethoxy-benzenesulfonic acid 1H-indol-5-y...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098053 (3-Amino-4-methoxy-benzenesulfonic acid 3,4,5-trime...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098050 (4-Methoxy-benzenesulfonic acid 3,4,5-trimethoxy-ph...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098049 (4-Dimethylamino-benzenesulfonic acid 3,4,5-trimeth...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50098057 (CHEMBL169800 \| Toluene-4-sulfonic acid 3,4,5-trime...) Show SMILES COc1cc(OS(=O)(=O)c2ccc(C)cc2)cc(OC)c1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%