Affinity Data by PubMed id=11714872

PubMed code 11714872

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (BOVINE)	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (RAT)	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM85826 ((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (RAT)	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM85827 ((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...) Show SMILES CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 883-93 (2001) BindingDB Entry DOI: 10.7270/Q2PK0DQ2
AstraZeneca R&D Curated by PDSP K_i Database					More data for this Ligand-Target Pair

* indicates data uncertainty>20%