Affinity Data by PubMed id=11855983

PubMed code 11855983

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078513 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110216 (8,9-Dichloro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]quin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110211 (8,9-Dichloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110213 (8-Chloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1,5-c...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110223 (8-Chloro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]quinazol...) Show SMILES OC(=O)c1cc2c3ccc(Cl)cc3[nH]c(=O)n2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110210 (8-Chloro-9-nitro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Percent Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110217 (8,9-Dichloro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]quin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50052298 (5-Oxo-5,6-dihydro-pyrazolo[1,5-c]quinazoline-2-car...) Show SMILES OC(=O)c1cc2c3ccccc3[nH]c(=O)n2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110221 (5-Oxo-1,5,6,10b-tetrahydro-pyrazolo[1,5-c]quinazol...) Show SMILES OC(=O)C1=NN2C(C1)c1ccccc1NC2=O \|t:3\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110222 (8,9-Dichloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110209 (8-Chloro-9-(3-formyl-pyrrol-1-yl)-5-oxo-5,6-dihydr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50229505 (8-Chloro-5-oxo-9-[1,2,4]triazol-4-yl-5,6-dihydro-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110224 (8-Chloro-9-nitro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110215 (8-Chloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1,5-c...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110214 (8-Chloro-5-oxo-5,6-dihydro-pyrazolo[1,5-c]quinazol...) Show SMILES CCOC(=O)c1cc2c3ccc(Cl)cc3[nH]c(=O)n2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50052308 (5-Oxo-5,6-dihydro-pyrazolo[1,5-c]quinazoline-2-car...) Show SMILES CCOC(=O)c1cc2c3ccccc3[nH]c(=O)n2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Glycine from N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50092637 (7-Chloro-4-oxo-8-[1,2,4]triazol-4-yl-4,5-dihydro-[...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110220 (8-Chloro-9-(3-formyl-pyrrol-1-yl)-5-oxo-5,6-dihydr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%