Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate carboxypeptidase 2 (Rattus norvegicus) | BDBM50116251 (2-{[3-(4-Amino-benzoylamino)-3-carboxy-propyl]-hyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Glutamate carboxypeptidase-II using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase 2 (Rattus norvegicus) | BDBM50116253 (2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Glutamate carboxypeptidase-II using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase 2 (Rattus norvegicus) | BDBM50116250 (2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Glutamate carboxypeptidase-II using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase 2 (Rattus norvegicus) | BDBM50116252 (2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Glutamate carboxypeptidase-II using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human)) | BDBM50116252 (2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Folylpoly-gamma-glutamyl synthetase | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human)) | BDBM50116250 (2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Folylpoly-gamma-glutamyl synthetase | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human)) | BDBM50116253 (2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propy...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Folylpoly-gamma-glutamyl synthetase | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human)) | BDBM50116251 (2-{[3-(4-Amino-benzoylamino)-3-carboxy-propyl]-hyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit Folylpoly-gamma-glutamyl synthetase | Bioorg Med Chem Lett 12: 2189-92 (2002) BindingDB Entry DOI: 10.7270/Q21835TN | |||||||||||
More data for this Ligand-Target Pair |