Affinity Data by PubMed id=12639573

PubMed code 12639573

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125092 (1-Benzyl-4-(3-methoxy-benzyl)-piperazine \| CHEMBL1...) Show SMILES COc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125098 (1-Benzyl-4-(3-chloro-benzyl)-piperazine \| CHEMBL16...) Show SMILES Clc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125099 (1-Benzyl-4-(4-methoxy-benzyl)-piperazine \| 1-benzy...) Show SMILES COc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125093 (1-Benzyl-4-(3,4-dichloro-benzyl)-piperazine \| CHEM...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1Cl Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125095 (1-Benzyl-4-(4-chloro-benzyl)-piperazine \| CHEMBL16...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 \| [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125094 (1-Benzyl-4-(2-chloro-benzyl)-piperazine \| CHEMBL34...) Show SMILES Clc1ccccc1CN1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125096 (1,4-Dibenzyl-piperazine \| 1,4-Dibenzyl-piperazine,...) Show SMILES C(N1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125097 (1-Benzyl-4-(2,4-dichloro-benzyl)-piperazine \| CHEM...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%