Affinity Data by PubMed id=12798316

PubMed code 12798316

Found 25 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50129227 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-isopro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129246 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-tert-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129237 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...) Show SMILES Cc1c(c[nH]c1C(=O)OCC1CC1)C(=O)OC(C)(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129231 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...) Show SMILES CCCOC(=O)c1[nH]cc(C(=O)OC(C)(C)C)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129226 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid di-tert-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129224 (5-Chloro-3-methyl-1H-pyrrole-2,4-dicarboxylic acid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129235 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pentaf...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129240 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(1-eth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129241 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...) Show SMILES CCOC(=O)c1[nH]cc(C(=O)OC(C)(C)C)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129239 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(2-dim...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129244 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pyridi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129230 (1,3,5-Trimethyl-1H-pyrrole-2,4-dicarboxylic acid 4...) Show SMILES CCCOC(=O)c1c(C)c(C(=O)OC(C)(C)C)c(C)n1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibitory concentration required against rat mGluR1a in CHO cells using the CDP-DAG accumulation method				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129233 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129222 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pyrimi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129225 (5-Formyl-3-methyl-1H-pyrrole-2,4-dicarboxylic acid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129242 (3,5-Dimethyl-pyrrole-1,2,4-tricarboxylic acid 1,4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibitory concentration required against rat mGluR1a in CHO cells using the CDP-DAG accumulation method				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129229 (5-(Cyclopropylmethyl-carbamoyl)-3-methyl-1H-pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129223 (5-Acetoxymethyl-3-methyl-1H-pyrrole-2,4-dicarboxyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129238 (4-Methyl-5-(pyridin-2-ylsulfanylcarbonyl)-1H-pyrro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129232 (4-Methyl-1H-pyrrole-2,3,5-tricarboxylic acid 3-ter...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129236 (3-Methyl-5-(pyridin-2-ylsulfanylcarbonyl)-1H-pyrro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129228 (1-(3-Methoxy-propyl)-3,5-dimethyl-1H-pyrrole-2,4-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129234 (5-Hydroxymethyl-3-methyl-1H-pyrrole-2,4-dicarboxyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129243 (1-Allyloxycarbonylmethyl-3,5-dimethyl-1H-pyrrole-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50129245 (3,5-Dimethyl-1H-pyrrole-2,4-dicarboxylic acid 2-pr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%