Affinity Data by PubMed id=12877587

PubMed code 12877587

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131661 (CHEMBL116944 \| N-(3-Hydroxycarbamoyl-1-hydroxymeth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-2 (MMP-2)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131661 (CHEMBL116944 \| N-(3-Hydroxycarbamoyl-1-hydroxymeth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-9 (MMP-9)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131660 (CHEMBL118497 \| Succinic acid mono-[4-hydroxycarbam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-2 (MMP-2)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50131660 (CHEMBL118497 \| Succinic acid mono-[4-hydroxycarbam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12 (MMP-12)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131660 (CHEMBL118497 \| Succinic acid mono-[4-hydroxycarbam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-9 (MMP-9)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50131661 (CHEMBL116944 \| N-(3-Hydroxycarbamoyl-1-hydroxymeth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
National Cardiovascular Center Research Institute Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloprotease-12 (MMP-12)				J Med Chem 46: 3497-501 (2003) Article DOI: 10.1021/jm020356g BindingDB Entry DOI: 10.7270/Q2862FT2
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%