Affinity Data by PubMed id=1360027

PubMed code 1360027

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002313 (2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002310 (3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...) Show SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002314 (2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002309 (2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002311 (2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...) Show SMILES CCCN(CCc1ccccc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50002313 (2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002312 (2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...) Show SMILES CCCN(CCC)CCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002314 (2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002309 (2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002311 (2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...) Show SMILES CCCN(CCc1ccccc1)CCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002315 (5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide \| ...) Show SMILES NCCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002315 (5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide \| ...) Show SMILES NCCc1ccc(Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002312 (2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...) Show SMILES CCCN(CCC)CCc1ccc(Cl)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002310 (3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...) Show SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%