Affinity Data by PubMed id=14643310

PubMed code 14643310

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50136246 ((S)-3-{(R)-2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]nap...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50136245 ((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-{(S)-2-oxo-3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50136244 ((S)-3-{(S)-2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]nap...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50136247 ((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-{(R)-2-oxo-3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50116975 ((S)-3-Quinolin-3-yl-3-(5-5,6,7,8-tetrahydro-[1,8]n...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50116981 ((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-(5-5,6,7,8-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrin				Bioorg Med Chem Lett 13: 4285-8 (2003) BindingDB Entry DOI: 10.7270/Q25D8T08
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%