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PubMed code 15341942

Compile data set for download or QSAR
Found 57 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152425
PNG
(8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine | CH...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H22N2O/c1-11(10-16(2,3)4)19-13-7-5-6-12-8-9-14(17)18-15(12)13/h5-9,11H,10H2,1-4H3,(H2,17,18)
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n/an/a 20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152406
PNG
(8-(2-Methyl-cyclohexyloxy)-quinolin-2-ylamine | CH...)
Show SMILES CC1CCCCC1Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H20N2O/c1-11-5-2-3-7-13(11)19-14-8-4-6-12-9-10-15(17)18-16(12)14/h4,6,8-11,13H,2-3,5,7H2,1H3,(H2,17,18)
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n/an/a 32n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152401
PNG
(8-(2-Methyl-butoxy)-quinolin-2-ylamine | CHEMBL362...)
Show SMILES CCC(C)COc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-3-10(2)9-17-12-6-4-5-11-7-8-13(15)16-14(11)12/h4-8,10H,3,9H2,1-2H3,(H2,15,16)
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n/an/a 36n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152410
PNG
(8-Cyclopentylmethoxy-quinolin-2-ylamine | CHEMBL18...)
Show SMILES Nc1ccc2cccc(OCC3CCCC3)c2n1
Show InChI InChI=1S/C15H18N2O/c16-14-9-8-12-6-3-7-13(15(12)17-14)18-10-11-4-1-2-5-11/h3,6-9,11H,1-2,4-5,10H2,(H2,16,17)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152442
PNG
(CHEMBL184520 | [5-(2-Chloro-phenyl)-furan-2-ylmeth...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(NCc3ccc(o3)-c3ccccc3Cl)nc12
Show InChI InChI=1S/C27H29ClN2O2/c1-18(16-27(2,3)4)31-24-11-7-8-19-12-15-25(30-26(19)24)29-17-20-13-14-23(32-20)21-9-5-6-10-22(21)28/h5-15,18H,16-17H2,1-4H3,(H,29,30)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152424
PNG
(8-Cyclohexylmethoxy-quinolin-2-ylamine | A-224940 ...)
Show SMILES Nc1ccc2cccc(OCC3CCCCC3)c2n1
Show InChI InChI=1S/C16H20N2O/c17-15-10-9-13-7-4-8-14(16(13)18-15)19-11-12-5-2-1-3-6-12/h4,7-10,12H,1-3,5-6,11H2,(H2,17,18)
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n/an/a 90n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152416
PNG
(8-(1-Methyl-butoxy)-quinolin-2-ylamine | CHEMBL187...)
Show SMILES CCCC(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-3-5-10(2)17-12-7-4-6-11-8-9-13(15)16-14(11)12/h4,6-10H,3,5H2,1-2H3,(H2,15,16)
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n/an/a 105n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152415
PNG
(8-(Tetrahydro-furan-3-ylmethoxy)-quinolin-2-ylamin...)
Show SMILES Nc1ccc2cccc(OCC3CCOC3)c2n1
Show InChI InChI=1S/C14H16N2O2/c15-13-5-4-11-2-1-3-12(14(11)16-13)18-9-10-6-7-17-8-10/h1-5,10H,6-9H2,(H2,15,16)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152433
PNG
(8-(3-Methoxy-3-methyl-butoxy)-quinolin-2-ylamine |...)
Show SMILES COC(C)(C)CCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C15H20N2O2/c1-15(2,18-3)9-10-19-12-6-4-5-11-7-8-13(16)17-14(11)12/h4-8H,9-10H2,1-3H3,(H2,16,17)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152422
PNG
(8-(Bicyclo[2.2.1]hept-2-ylmethoxy)-quinolin-2-ylam...)
Show SMILES Nc1ccc2cccc(OCC3CC4CCC3C4)c2n1 |THB:10:11:17:15.14|
Show InChI InChI=1S/C17H20N2O/c18-16-7-6-12-2-1-3-15(17(12)19-16)20-10-14-9-11-4-5-13(14)8-11/h1-3,6-7,11,13-14H,4-5,8-10H2,(H2,18,19)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152409
PNG
(8-Cycloheptyloxy-quinolin-2-ylamine | CHEMBL184394)
Show SMILES Nc1ccc2cccc(OC3CCCCCC3)c2n1
Show InChI InChI=1S/C16H20N2O/c17-15-11-10-12-6-5-9-14(16(12)18-15)19-13-7-3-1-2-4-8-13/h5-6,9-11,13H,1-4,7-8H2,(H2,17,18)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152412
PNG
(8-sec-Butoxy-quinolin-2-ylamine | CHEMBL186818)
Show SMILES CCC(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C13H16N2O/c1-3-9(2)16-11-6-4-5-10-7-8-12(14)15-13(10)11/h4-9H,3H2,1-2H3,(H2,14,15)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152432
PNG
(8-(2-Ethyl-1-methyl-butoxy)-quinolin-2-ylamine | C...)
Show SMILES CCC(CC)C(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H22N2O/c1-4-12(5-2)11(3)19-14-8-6-7-13-9-10-15(17)18-16(13)14/h6-12H,4-5H2,1-3H3,(H2,17,18)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152435
PNG
(8-(1,2-Dimethyl-propoxy)-quinolin-2-ylamine | CHEM...)
Show SMILES CC(C)C(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-9(2)10(3)17-12-6-4-5-11-7-8-13(15)16-14(11)12/h4-10H,1-3H3,(H2,15,16)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152403
PNG
(8-(3,3-Dimethyl-butoxy)-quinolin-2-ylamine | CHEMB...)
Show SMILES CC(C)(C)CCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C15H20N2O/c1-15(2,3)9-10-18-12-6-4-5-11-7-8-13(16)17-14(11)12/h4-8H,9-10H2,1-3H3,(H2,16,17)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152439
PNG
(8-(2-tert-Butoxy-1-methyl-ethoxy)-quinolin-2-ylami...)
Show SMILES CC(COC(C)(C)C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H22N2O2/c1-11(10-19-16(2,3)4)20-13-7-5-6-12-8-9-14(17)18-15(12)13/h5-9,11H,10H2,1-4H3,(H2,17,18)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152405
PNG
(CHEMBL184446 | Methyl-[8-(1,3,3-trimethyl-butoxy)-...)
Show SMILES CNc1ccc2cccc(OC(C)CC(C)(C)C)c2n1
Show InChI InChI=1S/C17H24N2O/c1-12(11-17(2,3)4)20-14-8-6-7-13-9-10-15(18-5)19-16(13)14/h6-10,12H,11H2,1-5H3,(H,18,19)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152447
PNG
(8-(1-Ethyl-propoxy)-quinolin-2-ylamine | CHEMBL185...)
Show SMILES CCC(CC)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-3-11(4-2)17-12-7-5-6-10-8-9-13(15)16-14(10)12/h5-9,11H,3-4H2,1-2H3,(H2,15,16)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152404
PNG
(8-(4-Methyl-cyclohexyloxy)-quinolin-2-ylamine | CH...)
Show SMILES CC1CCC(CC1)Oc1cccc2ccc(N)nc12 |(-5.22,-4.11,;-3.86,-3.36,;-3.85,-1.83,;-2.53,-1.05,;-1.2,-1.83,;-1.2,-3.36,;-2.53,-4.14,;.14,-1.05,;.14,.48,;-1.2,1.25,;-1.2,2.8,;.14,3.58,;1.45,2.8,;2.8,3.58,;4.11,2.81,;4.14,1.27,;5.48,.51,;2.81,.51,;1.45,1.25,)|
Show InChI InChI=1S/C16H20N2O/c1-11-5-8-13(9-6-11)19-14-4-2-3-12-7-10-15(17)18-16(12)14/h2-4,7,10-11,13H,5-6,8-9H2,1H3,(H2,17,18)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152434
PNG
(8-Cyclohexyloxy-quinolin-2-ylamine | CHEMBL185235)
Show SMILES Nc1ccc2cccc(OC3CCCCC3)c2n1
Show InChI InChI=1S/C15H18N2O/c16-14-10-9-11-5-4-8-13(15(11)17-14)18-12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7H2,(H2,16,17)
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n/an/a 361n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152444
PNG
(8-Cyclobutylmethoxy-quinolin-2-ylamine | CHEMBL184...)
Show SMILES Nc1ccc2cccc(OCC3CCC3)c2n1
Show InChI InChI=1S/C14H16N2O/c15-13-8-7-11-5-2-6-12(14(11)16-13)17-9-10-3-1-4-10/h2,5-8,10H,1,3-4,9H2,(H2,15,16)
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n/an/a 432n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152417
PNG
(8-Isopropoxy-quinolin-2-ylamine | CHEMBL365254)
Show SMILES CC(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C12H14N2O/c1-8(2)15-10-5-3-4-9-6-7-11(13)14-12(9)10/h3-8H,1-2H3,(H2,13,14)
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n/an/a 437n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152446
PNG
(8-(2-Cyclopropyl-ethoxy)-quinolin-2-ylamine | CHEM...)
Show SMILES Nc1ccc2cccc(OCCC3CC3)c2n1
Show InChI InChI=1S/C14H16N2O/c15-13-7-6-11-2-1-3-12(14(11)16-13)17-9-8-10-4-5-10/h1-3,6-7,10H,4-5,8-9H2,(H2,15,16)
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n/an/a 492n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152425
PNG
(8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine | CH...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H22N2O/c1-11(10-16(2,3)4)19-13-7-5-6-12-8-9-14(17)18-15(12)13/h5-9,11H,10H2,1-4H3,(H2,17,18)
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n/an/a 550n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152425
PNG
(8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine | CH...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H22N2O/c1-11(10-16(2,3)4)19-13-7-5-6-12-8-9-14(17)18-15(12)13/h5-9,11H,10H2,1-4H3,(H2,17,18)
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n/an/a 550n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152449
PNG
(8-Pentyloxy-quinolin-2-ylamine | CHEMBL186481)
Show SMILES CCCCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-2-3-4-10-17-12-7-5-6-11-8-9-13(15)16-14(11)12/h5-9H,2-4,10H2,1H3,(H2,15,16)
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n/an/a 580n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152418
PNG
(8-(2-Methoxy-1-methyl-ethoxy)-quinolin-2-ylamine |...)
Show SMILES COCC(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C13H16N2O2/c1-9(8-16-2)17-11-5-3-4-10-6-7-12(14)15-13(10)11/h3-7,9H,8H2,1-2H3,(H2,14,15)
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n/an/a 606n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152452
PNG
(8-(3-Methyl-butoxy)-quinolin-2-ylamine | CHEMBL184...)
Show SMILES CC(C)CCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O/c1-10(2)8-9-17-12-5-3-4-11-6-7-13(15)16-14(11)12/h3-7,10H,8-9H2,1-2H3,(H2,15,16)
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n/an/a 614n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152430
PNG
(8-(3-Methyl-cyclohexyloxy)-quinolin-2-ylamine | CH...)
Show SMILES CC1CCCC(C1)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C16H20N2O/c1-11-4-2-6-13(10-11)19-14-7-3-5-12-8-9-15(17)18-16(12)14/h3,5,7-9,11,13H,2,4,6,10H2,1H3,(H2,17,18)
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n/an/a 640n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152402
PNG
(8-(3,3,3-trifluoropropoxy)quinolin-2-amine | CHEMB...)
Show SMILES Nc1ccc2cccc(OCCC(F)(F)F)c2n1
Show InChI InChI=1S/C12H11F3N2O/c13-12(14,15)6-7-18-9-3-1-2-8-4-5-10(16)17-11(8)9/h1-5H,6-7H2,(H2,16,17)
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n/an/a 722n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152408
PNG
(8-Butoxy-quinolin-2-ylamine | CHEMBL186659)
Show SMILES CCCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C13H16N2O/c1-2-3-9-16-11-6-4-5-10-7-8-12(14)15-13(10)11/h4-8H,2-3,9H2,1H3,(H2,14,15)
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n/an/a 789n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152414
PNG
(8-[2-(2-Methoxy-ethoxy)-ethoxy]-quinolin-2-ylamine...)
Show SMILES Nc1ccc2cccc(OCCC3CCCCC3)c2n1
Show InChI InChI=1S/C17H22N2O/c18-16-10-9-14-7-4-8-15(17(14)19-16)20-12-11-13-5-2-1-3-6-13/h4,7-10,13H,1-3,5-6,11-12H2,(H2,18,19)
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n/an/a 808n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152426
PNG
(8-Hexyloxy-quinolin-2-ylamine | CHEMBL187295)
Show SMILES CCCCCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C15H20N2O/c1-2-3-4-5-11-18-13-8-6-7-12-9-10-14(16)17-15(12)13/h6-10H,2-5,11H2,1H3,(H2,16,17)
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n/an/a 818n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152437
PNG
(8-(3-Methyl-cyclopentyloxy)-quinolin-2-ylamine | C...)
Show SMILES CC1CCC(C1)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C15H18N2O/c1-10-5-7-12(9-10)18-13-4-2-3-11-6-8-14(16)17-15(11)13/h2-4,6,8,10,12H,5,7,9H2,1H3,(H2,16,17)
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n/an/a 823n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152443
PNG
(8-(2-Ethoxy-1-methyl-ethoxy)-quinolin-2-ylamine | ...)
Show SMILES CCOCC(C)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O2/c1-3-17-9-10(2)18-12-6-4-5-11-7-8-13(15)16-14(11)12/h4-8,10H,3,9H2,1-2H3,(H2,15,16)
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n/an/a 1.07E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152441
PNG
(8-Propoxy-quinolin-2-ylamine | CHEMBL427153)
Show SMILES CCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C12H14N2O/c1-2-8-15-10-5-3-4-9-6-7-11(13)14-12(9)10/h3-7H,2,8H2,1H3,(H2,13,14)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50025466
PNG
(8-Methoxy-quinolin-2-ylamine | CHEMBL77072)
Show SMILES COc1cccc2ccc(N)nc12
Show InChI InChI=1S/C10H10N2O/c1-13-8-4-2-3-7-5-6-9(11)12-10(7)8/h2-6H,1H3,(H2,11,12)
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n/an/a 1.59E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152445
PNG
(8-(2-Methyl-cyclopropylmethoxy)-quinolin-2-ylamine...)
Show SMILES CC1CC1COc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H16N2O/c1-9-7-11(9)8-17-12-4-2-3-10-5-6-13(15)16-14(10)12/h2-6,9,11H,7-8H2,1H3,(H2,15,16)
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n/an/a 1.64E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152440
PNG
(8-(1,3,3-Trimethyl-butoxy)-quinoline | CHEMBL36481...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2cccnc12
Show InChI InChI=1S/C16H21NO/c1-12(11-16(2,3)4)18-14-9-5-7-13-8-6-10-17-15(13)14/h5-10,12H,11H2,1-4H3
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152419
PNG
(CHEMBL184754 | Dimethyl-[8-(1,3,3-trimethyl-butoxy...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(nc12)N(C)C
Show InChI InChI=1S/C18H26N2O/c1-13(12-18(2,3)4)21-15-9-7-8-14-10-11-16(20(5)6)19-17(14)15/h7-11,13H,12H2,1-6H3
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152421
PNG
(8-(2-Methoxy-ethoxy)-quinolin-2-ylamine | CHEMBL18...)
Show SMILES COCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C12H14N2O2/c1-15-7-8-16-10-4-2-3-9-5-6-11(13)14-12(9)10/h2-6H,7-8H2,1H3,(H2,13,14)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152450
PNG
(8-Cyclopropylmethoxy-quinolin-2-ylamine | CHEMBL36...)
Show SMILES Nc1ccc2cccc(OCC3CC3)c2n1
Show InChI InChI=1S/C13H14N2O/c14-12-7-6-10-2-1-3-11(13(10)15-12)16-8-9-4-5-9/h1-3,6-7,9H,4-5,8H2,(H2,14,15)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152427
PNG
(2-Pyrrolidin-1-yl-8-(1,3,3-trimethyl-butoxy)-quino...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(nc12)N1CCCC1
Show InChI InChI=1S/C20H28N2O/c1-15(14-20(2,3)4)23-17-9-7-8-16-10-11-18(21-19(16)17)22-12-5-6-13-22/h7-11,15H,5-6,12-14H2,1-4H3
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152431
PNG
(8-Pent-3-ynyloxy-quinolin-2-ylamine | CHEMBL426971)
Show SMILES CC#CCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H14N2O/c1-2-3-4-10-17-12-7-5-6-11-8-9-13(15)16-14(11)12/h5-9H,4,10H2,1H3,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152407
PNG
(2-Piperidin-1-yl-8-(1,3,3-trimethyl-butoxy)-quinol...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(nc12)N1CCCCC1
Show InChI InChI=1S/C21H30N2O/c1-16(15-21(2,3)4)24-18-10-8-9-17-11-12-19(22-20(17)18)23-13-6-5-7-14-23/h8-12,16H,5-7,13-15H2,1-4H3
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152453
PNG
(8-(2-Ethoxy-ethoxy)-quinolin-2-ylamine | CHEMBL185...)
Show SMILES CCOCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C13H16N2O2/c1-2-16-8-9-17-11-5-3-4-10-6-7-12(14)15-13(10)11/h3-7H,2,8-9H2,1H3,(H2,14,15)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152436
PNG
(8-Pent-2-ynyloxy-quinolin-2-ylamine | CHEMBL366307)
Show SMILES CCC#CCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H14N2O/c1-2-3-4-10-17-12-7-5-6-11-8-9-13(15)16-14(11)12/h5-9H,2,10H2,1H3,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152451
PNG
(8-Isobutoxy-quinolin-2-ylamine | CHEMBL181798)
Show SMILES CC(C)COc1cccc2ccc(N)nc12
Show InChI InChI=1S/C13H16N2O/c1-9(2)8-16-11-5-3-4-10-6-7-12(14)15-13(10)11/h3-7,9H,8H2,1-2H3,(H2,14,15)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152423
PNG
(8-Cyclopentyloxy-quinolin-2-ylamine | CHEMBL363103)
Show SMILES Nc1ccc2cccc(OC3CCCC3)c2n1
Show InChI InChI=1S/C14H16N2O/c15-13-9-8-10-4-3-7-12(14(10)16-13)17-11-5-1-2-6-11/h3-4,7-9,11H,1-2,5-6H2,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152413
PNG
(8-[2-(2-Methoxy-ethoxy)-ethoxy]-quinolin-2-ylamine...)
Show SMILES COCCOCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O3/c1-17-7-8-18-9-10-19-12-4-2-3-11-5-6-13(15)16-14(11)12/h2-6H,7-10H2,1H3,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152411
PNG
(8-(3-Methyl-but-2-enyloxy)-quinolin-2-ylamine | CH...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1cccc2ccc(-[#7])nc12
Show InChI InChI=1S/C14H16N2O/c1-10(2)8-9-17-12-5-3-4-11-6-7-13(15)16-14(11)12/h3-8H,9H2,1-2H3,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152448
PNG
(8-(2-Methylsulfanyl-ethoxy)-quinolin-2-ylamine | C...)
Show SMILES CSCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C12H14N2OS/c1-16-8-7-15-10-4-2-3-9-5-6-11(13)14-12(9)10/h2-6H,7-8H2,1H3,(H2,13,14)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152438
PNG
(8-Cyclobutoxy-quinolin-2-ylamine | CHEMBL361902)
Show SMILES Nc1ccc2cccc(OC3CCC3)c2n1
Show InChI InChI=1S/C13H14N2O/c14-12-8-7-9-3-1-6-11(13(9)15-12)16-10-4-2-5-10/h1,3,6-8,10H,2,4-5H2,(H2,14,15)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152428
PNG
(8-(Tetrahydro-furan-2-ylmethoxy)-quinolin-2-ylamin...)
Show SMILES Nc1ccc2cccc(OCC3CCCO3)c2n1
Show InChI InChI=1S/C14H16N2O2/c15-13-7-6-10-3-1-5-12(14(10)16-13)18-9-11-4-2-8-17-11/h1,3,5-7,11H,2,4,8-9H2,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50149208
PNG
(2-Amino-quinolin-8-ol | CHEMBL119647)
Show SMILES Nc1ccc2cccc(O)c2n1
Show InChI InChI=1S/C9H8N2O/c10-8-5-4-6-2-1-3-7(12)9(6)11-8/h1-5,12H,(H2,10,11)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152420
PNG
(CHEMBL184099 | Cyclopropylmethyl-[8-(1,3,3-trimeth...)
Show SMILES CC(CC(C)(C)C)Oc1cccc2ccc(NCC3CC3)nc12
Show InChI InChI=1S/C20H28N2O/c1-14(12-20(2,3)4)23-17-7-5-6-16-10-11-18(22-19(16)17)21-13-15-8-9-15/h5-7,10-11,14-15H,8-9,12-13H2,1-4H3,(H,21,22)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152429
PNG
(8-(2-Isopropoxy-ethoxy)-quinolin-2-ylamine | CHEMB...)
Show SMILES CC(C)OCCOc1cccc2ccc(N)nc12
Show InChI InChI=1S/C14H18N2O2/c1-10(2)17-8-9-18-12-5-3-4-11-6-7-13(15)16-14(11)12/h3-7,10H,8-9H2,1-2H3,(H2,15,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4873-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.032
BindingDB Entry DOI: 10.7270/Q2QV3KZG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%