Affinity Data by PubMed id=15615528

PubMed code 15615528

Found 50 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM9475 (4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(Oc3ccccc3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9465 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole \| CHEMBL...) Show SMILES c1cn(cn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9483 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-4-phenyl-2H-c...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM8935 (5-[(6-methoxy-1-methyl-3,4-dihydronaphthalen-2-yl)...) Show SMILES COc1ccc2C(C)=C(Cc3cnc[nH]3)CCc2c1 \|t:7\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9477 (6-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9485 (7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(OCc3ccccc3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9476 (5-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1cc(Cn2ccnc2)c2ccc(=O)oc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9471 (4-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2c(Cn3ccnc3)cc(=O)oc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9478 (7-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1ccc2ccc(Cn3ccnc3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9473 (4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one \| ...) Show SMILES O=c1cc(OCCn2ccnc2)c2ccccc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9486 (6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione \| 6-...) Show SMILES S=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9470 (4-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1cc(Cn2ccnc2)c2ccccc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9469 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2cc(Cn3ccnc3)c(=O)oc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9462 (1-{2-methyl-5H-indeno[1,2-d]pyrimidin-5-yl}-1H-imi...) Show SMILES Cc1ncc2C(c3ccccc3-c2n1)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9464 (1-(9H-Fluoren-9-yl)-1H-imidazole \| CHEMBL225447 \| ...) Show SMILES c1cn(cn1)C1c2ccccc2-c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9472 (7-Methoxy-4-(1H-1,2,4-triazol-1-ylmethyl)-2H-chrom...) Show SMILES COc1ccc2c(Cn3cncn3)cc(=O)oc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9468 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole \| C...) Show SMILES c1ncn(n1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9482 (4-(1H-Imidazol-1-ylmethyl)-3-phenyl-2H-chromen-2-o...) Show SMILES O=c1oc2ccccc2c(Cn2ccnc2)c1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM8935 (5-[(6-methoxy-1-methyl-3,4-dihydronaphthalen-2-yl)...) Show SMILES COc1ccc2C(C)=C(Cc3cnc[nH]3)CCc2c1 \|t:7\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9463 (3-(1H-Imidazol-1-ylmethyl)-5H-indeno[1,2-c]pyridaz...) Show SMILES O=C1c2ccccc2-c2nnc(Cn3ccnc3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9480 (7-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one \| ...) Show SMILES O=c1ccc2ccc(OCCn3ccnc3)cc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9481 (8-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2ccc(=O)oc2c1Cn1ccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9483 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-4-phenyl-2H-c...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9484 (7-methoxy-4-(pyridin-4-yl)-2H-chromen-2-one \| Coum...) Show SMILES COc1ccc2c(cc(=O)oc2c1)-c1ccncc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9485 (7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(OCc3ccccc3)cc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9463 (3-(1H-Imidazol-1-ylmethyl)-5H-indeno[1,2-c]pyridaz...) Show SMILES O=C1c2ccccc2-c2nnc(Cn3ccnc3)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9475 (4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(Oc3ccccc3)cc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9467 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,3-triazole \| F...) Show SMILES c1cn(nn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9465 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole \| CHEMBL...) Show SMILES c1cn(cn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9476 (5-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1cc(Cn2ccnc2)c2ccc(=O)oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9473 (4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one \| ...) Show SMILES O=c1cc(OCCn2ccnc2)c2ccccc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9472 (7-Methoxy-4-(1H-1,2,4-triazol-1-ylmethyl)-2H-chrom...) Show SMILES COc1ccc2c(Cn3cncn3)cc(=O)oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9470 (4-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1cc(Cn2ccnc2)c2ccccc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9481 (8-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2ccc(=O)oc2c1Cn1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9480 (7-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one \| ...) Show SMILES O=c1ccc2ccc(OCCn3ccnc3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9479 (7-(1H-1,2,4-Triazol-1-ylmethyl)-2H-chromen-2-one \|...) Show SMILES O=c1ccc2ccc(Cn3cncn3)cc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9469 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2cc(Cn3ccnc3)c(=O)oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9468 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole \| C...) Show SMILES c1ncn(n1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9462 (1-{2-methyl-5H-indeno[1,2-d]pyrimidin-5-yl}-1H-imi...) Show SMILES Cc1ncc2C(c3ccccc3-c2n1)n1ccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9479 (7-(1H-1,2,4-Triazol-1-ylmethyl)-2H-chromen-2-one \|...) Show SMILES O=c1ccc2ccc(Cn3cncn3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9482 (4-(1H-Imidazol-1-ylmethyl)-3-phenyl-2H-chromen-2-o...) Show SMILES O=c1oc2ccccc2c(Cn2ccnc2)c1-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9477 (6-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9474 (4-[2-(1H-Imidazol-1-yl)ethoxy]-7-methoxy-2H-chrome...) Show SMILES COc1ccc2c(OCCn3ccnc3)cc(=O)oc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9486 (6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione \| 6-...) Show SMILES S=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9471 (4-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2c(Cn3ccnc3)cc(=O)oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9484 (7-methoxy-4-(pyridin-4-yl)-2H-chromen-2-one \| Coum...) Show SMILES COc1ccc2c(cc(=O)oc2c1)-c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9466 (4-(9-Phenyl-9H-fluoren-9-yl)-4H-1,2,4-triazole \| F...) Show SMILES c1nncn1C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9466 (4-(9-Phenyl-9H-fluoren-9-yl)-4H-1,2,4-triazole \| F...) Show SMILES c1nncn1C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9467 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,3-triazole \| F...) Show SMILES c1cn(nn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9478 (7-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one \| CHEM...) Show SMILES O=c1ccc2ccc(Cn3ccnc3)cc2o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
University of Bari					More data for this Ligand-Target Pair

* indicates data uncertainty>20%