Affinity Data by PubMed id=15658869

PubMed code 15658869

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin beta-2B chain (Bos taurus)	BDBM50159568 (1-Methyl-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...) Show SMILES COc1cc(\C=C/c2ccc3n(C)ccc3c2)cc(OC)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159538 (2-Methoxy-5-((Z)-2-naphthalen-2-yl-vinyl)-phenol \|...) Show SMILES COc1ccc(\C=C/c2ccc3ccccc3c2)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159552 (9-Methyl-3-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159583 (2-[(Z)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-naphthal...) Show SMILES COc1cc(\C=C/c2ccc3ccccc3c2)cc(OC)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159534 (2-[(Z)-2-(3,4-Dimethoxy-5-nitro-phenyl)-vinyl]-nap...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159562 (2-Methoxy-5-[(Z)-2-(4-methoxy-naphthalen-2-yl)-vin...) Show SMILES COc1ccc(\C=C/c2cc(OC)c3ccccc3c2)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159543 (5-[(Z)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-1H-indol...) Show SMILES COc1cc(\C=C/c2ccc3[nH]ccc3c2)cc(OC)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50159557 (1-Methyl-5-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...) Show SMILES COc1cc(\C=C\c2ccc3n(C)ccc3c2)cc(OC)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%