Affinity Data by PubMed id=16289813

PubMed code 16289813

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50177220 (2-(3-chlorostyryl)quinoline-7-carboxylic acid \| 2-...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cccc(Cl)c3)nc2c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Antiviral activity against HIV1 integrase				Bioorg Med Chem Lett 16: 1005-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.083 BindingDB Entry DOI: 10.7270/Q2QR4WQD
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50177219 ((E)-2-(3-chlorostyryl)quinolin-8-ol \| 2-(3-chloros...) Show SMILES Oc1cccc2ccc(\C=C\c3cccc(Cl)c3)nc12 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Antiviral activity against HIV1 integrase				Bioorg Med Chem Lett 16: 1005-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.083 BindingDB Entry DOI: 10.7270/Q2QR4WQD
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50177218 (2-((2,5-dichloro-4-nitrophenylamino)(methoxy)methy...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Antiviral activity against HIV1 integrase				Bioorg Med Chem Lett 16: 1005-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.083 BindingDB Entry DOI: 10.7270/Q2QR4WQD
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50177217 (2-methyl-5-nitrosoquinolin-8-ol \| CHEMBL202318) Show SMILES Cc1ccc2c(ccc(O)c2n1)N=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Antiviral activity against HIV1 integrase				Bioorg Med Chem Lett 16: 1005-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.083 BindingDB Entry DOI: 10.7270/Q2QR4WQD
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%