Affinity Data by PubMed id=17259979

PubMed code 17259979

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50248765 (1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of His6-tagged RSK2 C-terminal domian expressed in Escherichia coli after 30 mins				Nat Chem Biol 3: 156-60 (2007) Article DOI: 10.1038/nchembio859 BindingDB Entry DOI: 10.7270/Q22B8Z60
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50324685 (2-(3-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of His6-tagged RSK2 C-terminal domian expressed in Escherichia coli after 30 mins				Nat Chem Biol 3: 156-60 (2007) Article DOI: 10.1038/nchembio859 BindingDB Entry DOI: 10.7270/Q22B8Z60
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50324684 (3-(1-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of His6-tagged RSK2 C-terminal domian expressed in Escherichia coli after 30 mins				Nat Chem Biol 3: 156-60 (2007) Article DOI: 10.1038/nchembio859 BindingDB Entry DOI: 10.7270/Q22B8Z60
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50248765 (1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of PMA-stimulated RSK2 phosphorylation in HEK293 cells after 1 hr by western blotting analysis				Nat Chem Biol 3: 156-60 (2007) Article DOI: 10.1038/nchembio859 BindingDB Entry DOI: 10.7270/Q22B8Z60
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50324684 (3-(1-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of PMA-stimulated RSK2 phosphorylation in HEK293 cells after 1 hr by western blotting analysis				Nat Chem Biol 3: 156-60 (2007) Article DOI: 10.1038/nchembio859 BindingDB Entry DOI: 10.7270/Q22B8Z60
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%