Affinity Data by PubMed id=17395594

PubMed code 17395594

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK (unknown origin)				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK Tyr397 phosphorylation in human A431 cells by ELISA				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK Tyr397 phosphorylation in human FG cells after 60 mins by western blot analysis				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK Tyr397 phosphorylation in human SKOV3 cells after 60 mins by western blot analysis				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK Tyr397 phosphorylation in human PC3 cells after 60 mins by western blot analysis				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human CDK7/cyclinH/MAT1				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of FAK Tyr397 phosphorylation in human L3.6pl cells after 60 mins by western blot analysis				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human CDK1/cyclinB				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of Pyk2 (unknown origin)				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				J Biol Chem 282: 14845-52 (2007) Article DOI: 10.1074/jbc.M606695200 BindingDB Entry DOI: 10.7270/Q2J67GQH
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%