Affinity Data by PubMed id=17636914

PubMed code 17636914

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	220	-37.6	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM26103 (5-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(propa...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	500	-35.6	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM26102 (5-[2-(propan-2-yl)-4-[3-(trifluoromethyl)phenyl]ph...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	850	-34.3	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM26101 (5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-oxazol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	-31.7	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human))	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.70E+3	-28.9	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM26099 (5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-thiazo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.80E+3	-28.6	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human))	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.14E+4	-26.4	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	>-24.3	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	>-24.3	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM26104 (5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	>-24.3	n/a	n/a	n/a	n/a	n/a	7.4	22
University of California at Berkeley					Assay Description The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...				J Am Chem Soc 129: 9613-5 (2007) Article DOI: 10.1021/ja0727520 BindingDB Entry DOI: 10.7270/Q2PG1Q2M
University of California at Berkeley					More data for this Ligand-Target Pair

* indicates data uncertainty>20%