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PubMed code 17693086

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Homo sapiens (Human))
BDBM50109690
PNG
(3,4,5-Trihydroxy-benzoic acid 2-(4-hydroxy-phenyl)...)
Show SMILES Oc1ccc(CCOC(=O)c2cc(O)c(O)c(O)c2)cc1
Show InChI InChI=1S/C15H14O6/c16-11-3-1-9(2-4-11)5-6-21-15(20)10-7-12(17)14(19)13(18)8-10/h1-4,7-8,16-19H,5-6H2
KEGG

UniProtKB/SwissProt

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GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.93E+3n/an/an/an/an/an/a



AmorePacific Corporation

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in Melan-a cells


Bioorg Med Chem Lett 17: 5462-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.032
BindingDB Entry DOI: 10.7270/Q2BZ65RK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50219503
PNG
(2-hydroxyphenethyl 3,4,5-trihydroxybenzoate | CHEM...)
Show SMILES Oc1ccccc1CCOC(=O)c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C15H14O6/c16-11-4-2-1-3-9(11)5-6-21-15(20)10-7-12(17)14(19)13(18)8-10/h1-4,7-8,16-19H,5-6H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.45E+4n/an/an/an/an/an/a



AmorePacific Corporation

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in Melan-a cells


Bioorg Med Chem Lett 17: 5462-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.032
BindingDB Entry DOI: 10.7270/Q2BZ65RK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50219504
PNG
(3-hydroxyphenethyl 3,4,5-trihydroxybenzoate | CHEM...)
Show SMILES Oc1cccc(CCOC(=O)c2cc(O)c(O)c(O)c2)c1
Show InChI InChI=1S/C15H14O6/c16-11-3-1-2-9(6-11)4-5-21-15(20)10-7-12(17)14(19)13(18)8-10/h1-3,6-8,16-19H,4-5H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.52E+4n/an/an/an/an/an/a



AmorePacific Corporation

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in Melan-a cells


Bioorg Med Chem Lett 17: 5462-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.032
BindingDB Entry DOI: 10.7270/Q2BZ65RK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50219502
PNG
(4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...)
Show SMILES OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.03E+4n/an/an/an/an/an/a



AmorePacific Corporation

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in Melan-a cells


Bioorg Med Chem Lett 17: 5462-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.032
BindingDB Entry DOI: 10.7270/Q2BZ65RK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%