Found 43 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-secretase 2
(Homo sapiens (Human)) | BDBM50231481
(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2cccc(Br)c2)cc1)-c1ccccc1 Show InChI InChI=1S/C26H22BrN5O2/c27-20-8-4-7-19(15-20)25(34)30-21-11-9-18(10-12-21)23-14-13-22(17-5-2-1-3-6-17)32(23)16-24(33)31-26(28)29/h1-15H,16H2,(H,30,34)(H4,28,29,31,33) | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet 
| CHEMBL
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PC cid
PC sid
PDB
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| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE2 |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231500
(CHEMBL254057 | N-{2-[2-(4-methoxy-phenyl)-5-(4-phe...)Show SMILES COc1ccc(cc1)-c1ccc(-c2ccc(Oc3ccccc3)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C26H24N4O3/c1-32-20-11-7-18(8-12-20)23-15-16-24(30(23)17-25(31)29-26(27)28)19-9-13-22(14-10-19)33-21-5-3-2-4-6-21/h2-16H,17H2,1H3,(H4,27,28,29,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231492
(CHEMBL254058 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES COc1ccc(cc1)-c1ccc(-c2ccc(Oc3ccc(cc3)C(C)=O)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C28H26N4O4/c1-18(33)19-3-11-23(12-4-19)36-24-13-7-21(8-14-24)26-16-15-25(20-5-9-22(35-2)10-6-20)32(26)17-27(34)31-28(29)30/h3-16H,17H2,1-2H3,(H4,29,30,31,34) | PDB
MMDB
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231489
(CHEMBL398316 | N-{2-[2-(3-cyano-phenyl)-5-(4-pheno...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1cccc(c1)C#N)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H21N5O2/c27-16-18-5-4-6-20(15-18)24-14-13-23(31(24)17-25(32)30-26(28)29)19-9-11-22(12-10-19)33-21-7-2-1-3-8-21/h1-15H,17H2,(H4,28,29,30,32) | PDB
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| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231481
(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2cccc(Br)c2)cc1)-c1ccccc1 Show InChI InChI=1S/C26H22BrN5O2/c27-20-8-4-7-19(15-20)25(34)30-21-11-9-18(10-12-21)23-14-13-22(17-5-2-1-3-6-17)32(23)16-24(33)31-26(28)29/h1-15H,16H2,(H,30,34)(H4,28,29,31,33) | PDB
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| MMDB
PDB
Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231495
(CHEMBL399083 | N-{2-[2-(4-phenoxy-phenyl)-5-(4-tri...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(cc1)C(F)(F)F)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H21F3N4O2/c27-26(28,29)19-10-6-17(7-11-19)22-14-15-23(33(22)16-24(34)32-25(30)31)18-8-12-21(13-9-18)35-20-4-2-1-3-5-20/h1-15H,16H2,(H4,30,31,32,34) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231475
(CHEMBL254891 | N-{2-[2-benzo[b]thiophen-3-yl-5-(4-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(Oc2ccccc2)cc1)-c1csc2ccccc12 Show InChI InChI=1S/C27H22N4O2S/c28-27(29)30-26(32)16-31-23(14-15-24(31)22-17-34-25-9-5-4-8-21(22)25)18-10-12-20(13-11-18)33-19-6-2-1-3-7-19/h1-15,17H,16H2,(H4,28,29,30,32) | PDB
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| CHEMBL
PC cid
PC sid
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| Article
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| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM16753
(2-[2-(2-chlorophenyl)-5-[4-(4-acetylphenoxy)phenyl...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccccc3Cl)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23ClN4O3/c1-17(33)18-6-10-20(11-7-18)35-21-12-8-19(9-13-21)24-14-15-25(22-4-2-3-5-23(22)28)32(24)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
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| CHEMBL
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| MMDB
PDB
Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231496
(CHEMBL400087 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3cccc(c3)C#N)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C28H23N5O3/c1-18(34)20-5-9-23(10-6-20)36-24-11-7-21(8-12-24)25-13-14-26(22-4-2-3-19(15-22)16-29)33(25)17-27(35)32-28(30)31/h2-15H,17H2,1H3,(H4,30,31,32,35) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231487
(CHEMBL401172 | N-(2-{2-[4-(3-cyano-propoxy)-phenyl...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(OCCCC#N)cc1)-c1ccccc1 Show InChI InChI=1S/C23H23N5O2/c24-14-4-5-15-30-19-10-8-18(9-11-19)21-13-12-20(17-6-2-1-3-7-17)28(21)16-22(29)27-23(25)26/h1-3,6-13H,4-5,15-16H2,(H4,25,26,27,29) | PDB
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| CHEMBL
PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231470
(CHEMBL252007 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccc(cc3)C(F)(F)F)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C28H23F3N4O3/c1-17(36)18-4-10-22(11-5-18)38-23-12-6-20(7-13-23)25-15-14-24(35(25)16-26(37)34-27(32)33)19-2-8-21(9-3-19)28(29,30)31/h2-15H,16H2,1H3,(H4,32,33,34,37) | PDB
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| CHEMBL
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| Article
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| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231483
(CHEMBL401289 | N-(2-{2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccccc3)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H24N4O3/c1-18(32)19-7-11-22(12-8-19)34-23-13-9-21(10-14-23)25-16-15-24(20-5-3-2-4-6-20)31(25)17-26(33)30-27(28)29/h2-16H,17H2,1H3,(H4,28,29,30,33) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231502
(CHEMBL398315 | N-{2-[2-(2-chloro-phenyl)-5-(4-phen...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccccc1Cl)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H21ClN4O2/c26-21-9-5-4-8-20(21)23-15-14-22(30(23)16-24(31)29-25(27)28)17-10-12-19(13-11-17)32-18-6-2-1-3-7-18/h1-15H,16H2,(H4,27,28,29,31) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231478
(CHEMBL253241 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3cccc(F)c3)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23FN4O3/c1-17(33)18-5-9-22(10-6-18)35-23-11-7-19(8-12-23)24-13-14-25(20-3-2-4-21(28)15-20)32(24)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231503
(2,4-dichloro-N-{4-[1-(2-guanidino-2-oxo-ethyl)-5-p...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C26H21Cl2N5O2/c27-18-8-11-20(21(28)14-18)25(35)31-19-9-6-17(7-10-19)23-13-12-22(16-4-2-1-3-5-16)33(23)15-24(34)32-26(29)30/h1-14H,15H2,(H,31,35)(H4,29,30,32,34) | PDB
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| CHEMBL
PC cid
PC sid
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Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231490
(CHEMBL253863 | N-{2-[2-(4-phenoxy-phenyl)-5-phenyl...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(Oc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C25H22N4O2/c26-25(27)28-24(30)17-29-22(18-7-3-1-4-8-18)15-16-23(29)19-11-13-21(14-12-19)31-20-9-5-2-6-10-20/h1-16H,17H2,(H4,26,27,28,30) | PDB
MMDB
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231493
(CHEMBL253449 | N-{2-[2-(3-chloro-phenyl)-5-(4-phen...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1cccc(Cl)c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H21ClN4O2/c26-19-6-4-5-18(15-19)23-14-13-22(30(23)16-24(31)29-25(27)28)17-9-11-21(12-10-17)32-20-7-2-1-3-8-20/h1-15H,16H2,(H4,27,28,29,31) | PDB
MMDB
KEGG
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231498
(CHEMBL254092 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES COc1cccc(c1)-c1ccc(-c2ccc(Oc3ccc(cc3)C(C)=O)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C28H26N4O4/c1-18(33)19-6-10-22(11-7-19)36-23-12-8-20(9-13-23)25-14-15-26(21-4-3-5-24(16-21)35-2)32(25)17-27(34)31-28(29)30/h3-16H,17H2,1-2H3,(H4,29,30,31,34) | PDB
MMDB
KEGG
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231484
(CHEMBL252026 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccc(F)cc3)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23FN4O3/c1-17(33)18-4-10-22(11-5-18)35-23-12-6-20(7-13-23)25-15-14-24(19-2-8-21(28)9-3-19)32(25)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
MMDB
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UniChem
Similars
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PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231494
(CHEMBL252218 | N-{2-[2-(2-methoxy-phenyl)-5-(4-phe...)Show SMILES COc1ccccc1-c1ccc(-c2ccc(Oc3ccccc3)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C26H24N4O3/c1-32-24-10-6-5-9-21(24)23-16-15-22(30(23)17-25(31)29-26(27)28)18-11-13-20(14-12-18)33-19-7-3-2-4-8-19/h2-16H,17H2,1H3,(H4,27,28,29,31) | PDB
MMDB
KEGG
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| CHEMBL
PC cid
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UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231491
(4-bromo-N-{4-[1-(2-guanidino-2-oxo-ethyl)-5-phenyl...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2ccc(Br)cc2)cc1)-c1ccccc1 Show InChI InChI=1S/C26H22BrN5O2/c27-20-10-6-19(7-11-20)25(34)30-21-12-8-18(9-13-21)23-15-14-22(17-4-2-1-3-5-17)32(23)16-24(33)31-26(28)29/h1-15H,16H2,(H,30,34)(H4,28,29,31,33) | PDB
MMDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231473
(CHEMBL253031 | N-{2-[2-(3-fluoro-phenyl)-5-(4-phen...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1cccc(F)c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H21FN4O2/c26-19-6-4-5-18(15-19)23-14-13-22(30(23)16-24(31)29-25(27)28)17-9-11-21(12-10-17)32-20-7-2-1-3-8-20/h1-15H,16H2,(H4,27,28,29,31) | PDB
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PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231504
(CHEMBL252025 | N-{2-[2-(4-fluoro-phenyl)-5-(4-phen...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(Oc2ccccc2)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21FN4O2/c26-19-10-6-17(7-11-19)22-14-15-23(30(22)16-24(31)29-25(27)28)18-8-12-21(13-9-18)32-20-4-2-1-3-5-20/h1-15H,16H2,(H4,27,28,29,31) | PDB
MMDB
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Similars
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PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231497
(CHEMBL254091 | N-{2-[2-(3-methoxy-phenyl)-5-(4-phe...)Show SMILES COc1cccc(c1)-c1ccc(-c2ccc(Oc3ccccc3)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C26H24N4O3/c1-32-22-9-5-6-19(16-22)24-15-14-23(30(24)17-25(31)29-26(27)28)18-10-12-21(13-11-18)33-20-7-3-2-4-8-20/h2-16H,17H2,1H3,(H4,27,28,29,31) | PDB
MMDB
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Similars
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PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231482
(CHEMBL252219 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)Show SMILES COc1ccccc1-c1ccc(-c2ccc(Oc3ccc(cc3)C(C)=O)cc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C28H26N4O4/c1-18(33)19-7-11-21(12-8-19)36-22-13-9-20(10-14-22)24-15-16-25(23-5-3-4-6-26(23)35-2)32(24)17-27(34)31-28(29)30/h3-16H,17H2,1-2H3,(H4,29,30,31,34) | PDB
MMDB
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PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231488
(CHEMBL253214 | N-{2-[2-(4-ethoxy-phenyl)-5-phenyl-...)Show SMILES CCOc1ccc(cc1)-c1ccc(-c2ccccc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C21H22N4O2/c1-2-27-17-10-8-16(9-11-17)19-13-12-18(15-6-4-3-5-7-15)25(19)14-20(26)24-21(22)23/h3-13H,2,14H2,1H3,(H4,22,23,24,26) | PDB
MMDB
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| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231486
(CHEMBL401171 | N-{2-[2-(4-allyloxy-phenyl)-5-pheny...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(OCC=C)cc1)-c1ccccc1 Show InChI InChI=1S/C22H22N4O2/c1-2-14-28-18-10-8-17(9-11-18)20-13-12-19(16-6-4-3-5-7-16)26(20)15-21(27)25-22(23)24/h2-13H,1,14-15H2,(H4,23,24,25,27) | PDB
MMDB
KEGG
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Similars
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PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231485
(CHEMBL253420 | N-{2-[2-(4-butoxy-phenyl)-5-phenyl-...)Show SMILES CCCCOc1ccc(cc1)-c1ccc(-c2ccccc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C23H26N4O2/c1-2-3-15-29-19-11-9-18(10-12-19)21-14-13-20(17-7-5-4-6-8-17)27(21)16-22(28)26-23(24)25/h4-14H,2-3,15-16H2,1H3,(H4,24,25,26,28) | PDB
MMDB
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PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231479
(CHEMBL252190 | N-{4-[1-(2-guanidino-2-oxo-ethyl)-5...)Show SMILES COc1cccc(c1)C(=O)Nc1ccc(cc1)-c1ccc(-c2ccccc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C27H25N5O3/c1-35-22-9-5-8-20(16-22)26(34)30-21-12-10-19(11-13-21)24-15-14-23(18-6-3-2-4-7-18)32(24)17-25(33)31-27(28)29/h2-16H,17H2,1H3,(H,30,34)(H4,28,29,31,33) | PDB
MMDB
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| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231499
(CHEMBL253421 | N-(2-{2-[4-(4-cyano-benzyloxy)-phen...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(OCc2ccc(cc2)C#N)cc1)-c1ccccc1 Show InChI InChI=1S/C27H23N5O2/c28-16-19-6-8-20(9-7-19)18-34-23-12-10-22(11-13-23)25-15-14-24(21-4-2-1-3-5-21)32(25)17-26(33)31-27(29)30/h1-15H,17-18H2,(H4,29,30,31,33) | PDB
MMDB
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Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231474
(CHEMBL252626 | N-{2-[2-(2-chloro-phenyl)-5-(4-fluo...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccccc1Cl)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16ClFN4O/c20-15-4-2-1-3-14(15)17-10-9-16(12-5-7-13(21)8-6-12)25(17)11-18(26)24-19(22)23/h1-10H,11H2,(H4,22,23,24,26) | PDB
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Similars
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PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231501
(CHEMBL251828 | N-{2-[2-(2,5-dichloro-phenyl)-5-(4-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1cc(Cl)ccc1Cl)-c1ccc(F)cc1 Show InChI InChI=1S/C19H15Cl2FN4O/c20-12-3-6-15(21)14(9-12)17-8-7-16(11-1-4-13(22)5-2-11)26(17)10-18(27)25-19(23)24/h1-9H,10H2,(H4,23,24,25,27) | PDB
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Similars
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PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Homo sapiens (Human)) | BDBM50231481
(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2cccc(Br)c2)cc1)-c1ccccc1 Show InChI InChI=1S/C26H22BrN5O2/c27-20-8-4-7-19(15-20)25(34)30-21-11-9-18(10-12-21)23-14-13-22(17-5-2-1-3-6-17)32(23)16-24(33)31-26(28)29/h1-15H,16H2,(H,30,34)(H4,28,29,31,33) | PDB
MMDB
NCI pathway
Reactome pathway
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| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cathepsin D |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 2
(Homo sapiens (Human)) | BDBM16753
(2-[2-(2-chlorophenyl)-5-[4-(4-acetylphenoxy)phenyl...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccccc3Cl)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23ClN4O3/c1-17(33)18-6-10-20(11-7-18)35-21-12-8-19(9-13-21)24-14-15-25(22-4-2-3-5-23(22)28)32(24)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
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PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE2 |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231477
(CHEMBL404860 | N-{2-[2-(2-chloro-phenyl)-5-phenyl-...)Show InChI InChI=1S/C19H17ClN4O/c20-15-9-5-4-8-14(15)17-11-10-16(13-6-2-1-3-7-13)24(17)12-18(25)23-19(21)22/h1-11H,12H2,(H4,21,22,23,25) | PDB
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Similars
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PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231472
(CHEMBL399837 | N-{2-[2-(2,5-dichloro-phenyl)-5-phe...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1cc(Cl)ccc1Cl)-c1ccccc1 Show InChI InChI=1S/C19H16Cl2N4O/c20-13-6-7-15(21)14(10-13)17-9-8-16(12-4-2-1-3-5-12)25(17)11-18(26)24-19(22)23/h1-10H,11H2,(H4,22,23,24,26) | PDB
MMDB
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM16751
((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...)Show InChI InChI=1S/C19H18N4O/c20-19(21)22-18(24)13-23-16(14-7-3-1-4-8-14)11-12-17(23)15-9-5-2-6-10-15/h1-12H,13H2,(H4,20,21,22,24) | PDB
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Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM16753
(2-[2-(2-chlorophenyl)-5-[4-(4-acetylphenoxy)phenyl...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccccc3Cl)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23ClN4O3/c1-17(33)18-6-10-20(11-7-18)35-21-12-8-19(9-13-21)24-14-15-25(22-4-2-3-5-23(22)28)32(24)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 assessed as reduction of total cellular amyloid beta formation by ELISA |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231476
(CHEMBL399423 | N-[2-(2-Phenyl-5-m-tolyl-pyrrol-1-y...)Show SMILES Cc1cccc(c1)-c1ccc(-c2ccccc2)n1CC(=O)NC(N)=N Show InChI InChI=1S/C20H20N4O/c1-14-6-5-9-16(12-14)18-11-10-17(15-7-3-2-4-8-15)24(18)13-19(25)23-20(21)22/h2-12H,13H2,1H3,(H4,21,22,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 by FRET assay |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50231481
(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2cccc(Br)c2)cc1)-c1ccccc1 Show InChI InChI=1S/C26H22BrN5O2/c27-20-8-4-7-19(15-20)25(34)30-21-11-9-18(10-12-21)23-14-13-22(17-5-2-1-3-6-17)32(23)16-24(33)31-26(28)29/h1-15H,16H2,(H,30,34)(H4,28,29,31,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 assessed as reduction of total cellular amyloid beta formation by ELISA |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cathepsin D
(Homo sapiens (Human)) | BDBM16753
(2-[2-(2-chlorophenyl)-5-[4-(4-acetylphenoxy)phenyl...)Show SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3ccccc3Cl)n2CC(=O)NC(N)=N)cc1 Show InChI InChI=1S/C27H23ClN4O3/c1-17(33)18-6-10-20(11-7-18)35-21-12-8-19(9-13-21)24-14-15-25(22-4-2-3-5-23(22)28)32(24)16-26(34)31-27(29)30/h2-15H,16H2,1H3,(H4,29,30,31,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cathepsin D |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Beta-secretase 2
(Homo sapiens (Human)) | BDBM16751
((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...)Show InChI InChI=1S/C19H18N4O/c20-19(21)22-18(24)13-23-16(14-7-3-1-4-8-14)11-12-17(23)15-9-5-2-6-10-15/h1-12H,13H2,(H4,20,21,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of BACE2 |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Homo sapiens (Human)) | BDBM16751
((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...)Show InChI InChI=1S/C19H18N4O/c20-19(21)22-18(24)13-23-16(14-7-3-1-4-8-14)11-12-17(23)15-9-5-2-6-10-15/h1-12H,13H2,(H4,20,21,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cathepsin D |
Bioorg Med Chem Lett 18: 1063-6 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.010
BindingDB Entry DOI: 10.7270/Q22807CT |
More data for this
Ligand-Target Pair | |
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