Affinity Data by PubMed id=18232654

PubMed code 18232654

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM5718 (2,6,9-Trisubstituted purine deriv. 26 \| 2-{[6-(ben...) Show SMILES Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411620 (CHEMBL272186) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411621 (CHEMBL272400) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411618 (CHEMBL407018) Show SMILES CCOC(=O)c1cc2ccc3c4ccccc4[nH]c3c2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411624 (CHEMBL407487) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411619 (CHEMBL408543) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411622 (CHEMBL407486) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50411623 (CHEMBL272399) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%