Found 62 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377576
(CHEMBL401596)Show InChI InChI=1S/C15H17ClN2O/c1-11-8-13(16)4-5-14(11)19-15-6-7-17-9-12(15)10-18(2)3/h4-9H,10H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377573
(CHEMBL256136)Show InChI InChI=1S/C14H14BrClN2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(16)7-12(14)15/h3-8H,9H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377579
(CHEMBL403078)Show InChI InChI=1S/C15H17ClN2O2/c1-10-6-14(11(8-17-2)9-18-10)20-13-5-4-12(16)7-15(13)19-3/h4-7,9,17H,8H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377586
(CHEMBL257593)Show InChI InChI=1S/C15H17ClN2O2/c1-18(2)10-11-9-17-7-6-13(11)20-14-5-4-12(16)8-15(14)19-3/h4-9H,10H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377574
(CHEMBL256970)Show InChI InChI=1S/C16H19ClN2O/c1-11-7-14(17)5-6-15(11)20-16-8-12(2)18-9-13(16)10-19(3)4/h5-9H,10H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377575
(CHEMBL256137)Show InChI InChI=1S/C15H17ClN2O/c1-10-6-13(16)4-5-14(10)19-15-7-11(2)18-9-12(15)8-17-3/h4-7,9,17H,8H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50203945
((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)Show InChI InChI=1S/C18H28N2O/c1-14-4-3-5-16(15(14)2)13-20(18-6-9-19-12-18)17-7-10-21-11-8-17/h3-5,17-19H,6-13H2,1-2H3/t18-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371626
(CHEMBL402345)Show InChI InChI=1S/C18H21ClN2O3/c1-20-11-13-9-12(18(22)21(2)3)5-7-15(13)24-16-8-6-14(19)10-17(16)23-4/h5-10,20H,11H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377569
(CHEMBL260036)Show InChI InChI=1S/C14H14Cl2N2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(15)7-12(14)16/h3-8H,9H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50203945
((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)Show InChI InChI=1S/C18H28N2O/c1-14-4-3-5-16(15(14)2)13-20(18-6-9-19-12-18)17-7-10-21-11-8-17/h3-5,17-19H,6-13H2,1-2H3/t18-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377572
(CHEMBL402371)Show InChI InChI=1S/C14H14BrClN2O/c1-9-5-14(10(7-17-2)8-18-9)19-13-4-3-11(16)6-12(13)15/h3-6,8,17H,7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377585
(CHEMBL402000)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-9-14(17)5-6-15(12)20-16-7-8-18-10-13(16)11-19(2)3/h5-10H,4,11H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377578
(CHEMBL403080)Show InChI InChI=1S/C16H19ClN2O2/c1-11-7-15(12(9-18-11)10-19(2)3)21-14-6-5-13(17)8-16(14)20-4/h5-9H,10H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50188098
((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)Show InChI InChI=1S/C20H26N2O/c1-2-23-20-11-7-6-10-18(20)16-19(17-8-4-3-5-9-17)22-14-12-21-13-15-22/h3-11,19,21H,2,12-16H2,1H3/t19-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377584
(CHEMBL256511)Show InChI InChI=1S/C14H15ClN2O/c1-10-7-12(15)3-4-13(10)18-14-5-6-17-9-11(14)8-16-2/h3-7,9,16H,8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377580
(CHEMBL258449)Show InChI InChI=1S/C14H15ClN2O2/c1-16-8-10-9-17-6-5-12(10)19-13-4-3-11(15)7-14(13)18-2/h3-7,9,16H,8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50188098
((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)Show InChI InChI=1S/C20H26N2O/c1-2-23-20-11-7-6-10-18(20)16-19(17-8-4-3-5-9-17)22-14-12-21-13-15-22/h3-11,19,21H,2,12-16H2,1H3/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377585
(CHEMBL402000)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-9-14(17)5-6-15(12)20-16-7-8-18-10-13(16)11-19(2)3/h5-10H,4,11H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377571
(CHEMBL260038)Show InChI InChI=1S/C16H20N2O2/c1-11-5-6-14(16(7-11)19-4)20-15-8-12(2)18-10-13(15)9-17-3/h5-8,10,17H,9H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50375715
(CHEMBL256293)Show InChI InChI=1S/C17H21ClN2O/c1-5-13-9-15(18)6-7-16(13)21-17-8-12(2)19-10-14(17)11-20(3)4/h6-10H,5,11H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50375708
(CHEMBL403251)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-8-14(17)5-6-15(12)20-16-7-11(2)19-10-13(16)9-18-3/h5-8,10,18H,4,9H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50375708
(CHEMBL403251)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-8-14(17)5-6-15(12)20-16-7-11(2)19-10-13(16)9-18-3/h5-8,10,18H,4,9H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377583
(CHEMBL256135)Show InChI InChI=1S/C13H12BrClN2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(15)6-11(13)14/h2-6,8,16H,7H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377581
(CHEMBL260037)Show InChI InChI=1S/C15H17ClN2O2/c1-3-19-15-8-12(16)4-5-14(15)20-13-6-7-18-10-11(13)9-17-2/h4-8,10,17H,3,9H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377569
(CHEMBL260036)Show InChI InChI=1S/C14H14Cl2N2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(15)7-12(14)16/h3-8H,9H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377574
(CHEMBL256970)Show InChI InChI=1S/C16H19ClN2O/c1-11-7-14(17)5-6-15(11)20-16-8-12(2)18-9-13(16)10-19(3)4/h5-9H,10H2,1-4H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377578
(CHEMBL403080)Show InChI InChI=1S/C16H19ClN2O2/c1-11-7-15(12(9-18-11)10-19(2)3)21-14-6-5-13(17)8-16(14)20-4/h5-9H,10H2,1-4H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377573
(CHEMBL256136)Show InChI InChI=1S/C14H14BrClN2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(16)7-12(14)15/h3-8H,9H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50375715
(CHEMBL256293)Show InChI InChI=1S/C17H21ClN2O/c1-5-13-9-15(18)6-7-16(13)21-17-8-12(2)19-10-14(17)11-20(3)4/h6-10H,5,11H2,1-4H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50371626
(CHEMBL402345)Show InChI InChI=1S/C18H21ClN2O3/c1-20-11-13-9-12(18(22)21(2)3)5-7-15(13)24-16-8-6-14(19)10-17(16)23-4/h5-10,20H,11H2,1-4H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377576
(CHEMBL401596)Show InChI InChI=1S/C15H17ClN2O/c1-11-8-13(16)4-5-14(11)19-15-6-7-17-9-12(15)10-18(2)3/h4-9H,10H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377572
(CHEMBL402371)Show InChI InChI=1S/C14H14BrClN2O/c1-9-5-14(10(7-17-2)8-18-9)19-13-4-3-11(16)6-12(13)15/h3-6,8,17H,7H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377570
(CHEMBL259136)Show InChI InChI=1S/C13H12Cl2N2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(14)6-11(13)15/h2-6,8,16H,7H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377577
(CHEMBL257592)Show InChI InChI=1S/C15H17ClN2O/c1-3-11-8-13(16)4-5-14(11)19-15-6-7-18-10-12(15)9-17-2/h4-8,10,17H,3,9H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377586
(CHEMBL257593)Show InChI InChI=1S/C15H17ClN2O2/c1-18(2)10-11-9-17-7-6-13(11)20-14-5-4-12(16)8-15(14)19-3/h4-9H,10H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377575
(CHEMBL256137)Show InChI InChI=1S/C15H17ClN2O/c1-10-6-13(16)4-5-14(10)19-15-7-11(2)18-9-12(15)8-17-3/h4-7,9,17H,8H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377579
(CHEMBL403078)Show InChI InChI=1S/C15H17ClN2O2/c1-10-6-14(11(8-17-2)9-18-10)20-13-5-4-12(16)7-15(13)19-3/h4-7,9,17H,8H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377583
(CHEMBL256135)Show InChI InChI=1S/C13H12BrClN2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(15)6-11(13)14/h2-6,8,16H,7H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377577
(CHEMBL257592)Show InChI InChI=1S/C15H17ClN2O/c1-3-11-8-13(16)4-5-14(11)19-15-6-7-18-10-12(15)9-17-2/h4-8,10,17H,3,9H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377570
(CHEMBL259136)Show InChI InChI=1S/C13H12Cl2N2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(14)6-11(13)15/h2-6,8,16H,7H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50377582
(CHEMBL260039)Show InChI InChI=1S/C15H17FN2O/c1-10-6-13(16)4-5-14(10)19-15-7-11(2)18-9-12(15)8-17-3/h4-7,9,17H,8H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 231 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377584
(CHEMBL256511)Show InChI InChI=1S/C14H15ClN2O/c1-10-7-12(15)3-4-13(10)18-14-5-6-17-9-11(14)8-16-2/h3-7,9,16H,8H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377571
(CHEMBL260038)Show InChI InChI=1S/C16H20N2O2/c1-11-5-6-14(16(7-11)19-4)20-15-8-12(2)18-10-13(15)9-17-3/h5-8,10,17H,9H2,1-4H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377580
(CHEMBL258449)Show InChI InChI=1S/C14H15ClN2O2/c1-16-8-10-9-17-6-5-12(10)19-13-4-3-11(15)7-14(13)18-2/h3-7,9,16H,8H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377581
(CHEMBL260037)Show InChI InChI=1S/C15H17ClN2O2/c1-3-19-15-8-12(16)4-5-14(15)20-13-6-7-18-10-11(13)9-17-2/h4-8,10,17H,3,9H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 394 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50377582
(CHEMBL260039)Show InChI InChI=1S/C15H17FN2O/c1-10-6-13(16)4-5-14(10)19-15-7-11(2)18-9-12(15)8-17-3/h4-7,9,17H,8H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50203945
((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)Show InChI InChI=1S/C18H28N2O/c1-14-4-3-5-16(15(14)2)13-20(18-6-9-19-12-18)17-7-10-21-11-8-17/h3-5,17-19H,6-13H2,1-2H3/t18-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 727 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377574
(CHEMBL256970)Show InChI InChI=1S/C16H19ClN2O/c1-11-7-14(17)5-6-15(11)20-16-8-12(2)18-9-13(16)10-19(3)4/h5-9H,10H2,1-4H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377573
(CHEMBL256136)Show InChI InChI=1S/C14H14BrClN2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(16)7-12(14)15/h3-8H,9H2,1-2H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377569
(CHEMBL260036)Show InChI InChI=1S/C14H14Cl2N2O/c1-18(2)9-10-8-17-6-5-13(10)19-14-4-3-11(15)7-12(14)16/h3-8H,9H2,1-2H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377576
(CHEMBL401596)Show InChI InChI=1S/C15H17ClN2O/c1-11-8-13(16)4-5-14(11)19-15-6-7-17-9-12(15)10-18(2)3/h4-9H,10H2,1-3H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50188098
((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)Show InChI InChI=1S/C20H26N2O/c1-2-23-20-11-7-6-10-18(20)16-19(17-8-4-3-5-9-17)22-14-12-21-13-15-22/h3-11,19,21H,2,12-16H2,1H3/t19-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50371626
(CHEMBL402345)Show InChI InChI=1S/C18H21ClN2O3/c1-20-11-13-9-12(18(22)21(2)3)5-7-15(13)24-16-8-6-14(19)10-17(16)23-4/h5-10,20H,11H2,1-4H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377578
(CHEMBL403080)Show InChI InChI=1S/C16H19ClN2O2/c1-11-7-15(12(9-18-11)10-19(2)3)21-14-6-5-13(17)8-16(14)20-4/h5-9H,10H2,1-4H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50377578
(CHEMBL403080)Show InChI InChI=1S/C16H19ClN2O2/c1-11-7-15(12(9-18-11)10-19(2)3)21-14-6-5-13(17)8-16(14)20-4/h5-9H,10H2,1-4H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50377578
(CHEMBL403080)Show InChI InChI=1S/C16H19ClN2O2/c1-11-7-15(12(9-18-11)10-19(2)3)21-14-6-5-13(17)8-16(14)20-4/h5-9H,10H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50377574
(CHEMBL256970)Show InChI InChI=1S/C16H19ClN2O/c1-11-7-14(17)5-6-15(11)20-16-8-12(2)18-9-13(16)10-19(3)4/h5-9H,10H2,1-4H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50377574
(CHEMBL256970)Show InChI InChI=1S/C16H19ClN2O/c1-11-7-14(17)5-6-15(11)20-16-8-12(2)18-9-13(16)10-19(3)4/h5-9H,10H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377586
(CHEMBL257593)Show InChI InChI=1S/C15H17ClN2O2/c1-18(2)10-11-9-17-7-6-13(11)20-14-5-4-12(16)8-15(14)19-3/h4-9H,10H2,1-3H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50375715
(CHEMBL256293)Show InChI InChI=1S/C17H21ClN2O/c1-5-13-9-15(18)6-7-16(13)21-17-8-12(2)19-10-14(17)11-20(3)4/h6-10H,5,11H2,1-4H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50375708
(CHEMBL403251)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-8-14(17)5-6-15(12)20-16-7-11(2)19-10-13(16)9-18-3/h5-8,10,18H,4,9H2,1-3H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50377585
(CHEMBL402000)Show InChI InChI=1S/C16H19ClN2O/c1-4-12-9-14(17)5-6-15(12)20-16-7-8-18-10-13(16)11-19(2)3/h5-10H,4,11H2,1-3H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.082
BindingDB Entry DOI: 10.7270/Q2ZG6T44 |
More data for this
Ligand-Target Pair | |
Search and Browse
