Found 41 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412735
(CHEMBL454251)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)C(C)(C)C)c1cccc(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C33H43ClN4O/c1-23-35-29-10-5-6-11-30(29)38(23)28-21-26-12-13-27(22-28)37(26)19-16-33(24-8-7-9-25(34)20-24)14-17-36(18-15-33)31(39)32(2,3)4/h5-11,20,26-28H,12-19,21-22H2,1-4H3/t26-,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412739
(CHEMBL503033)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C35H40N4O/c1-26-36-32-14-8-9-15-33(32)39(26)31-24-29-16-17-30(25-31)38(29)23-20-35(28-12-6-3-7-13-28)18-21-37(22-19-35)34(40)27-10-4-2-5-11-27/h2-15,29-31H,16-25H2,1H3/t29-,30-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412762
(CHEMBL444938)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)OC(C)(C)C)c1cccc(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C33H43ClN4O2/c1-23-35-29-10-5-6-11-30(29)38(23)28-21-26-12-13-27(22-28)37(26)19-16-33(24-8-7-9-25(34)20-24)14-17-36(18-15-33)31(39)40-32(2,3)4/h5-11,20,26-28H,12-19,21-22H2,1-4H3/t26-,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412738
(CHEMBL445772)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)c1ccccc1)c1cccc(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C35H39ClN4O/c1-25-37-32-12-5-6-13-33(32)40(25)31-23-29-14-15-30(24-31)39(29)21-18-35(27-10-7-11-28(36)22-27)16-19-38(20-17-35)34(41)26-8-3-2-4-9-26/h2-13,22,29-31H,14-21,23-24H2,1H3/t29-,30-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.25 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412737
(CHEMBL501085)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)C(C)(C)C)c1ccc(Cl)c(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C33H42Cl2N4O/c1-22-36-29-7-5-6-8-30(29)39(22)26-20-24-10-11-25(21-26)38(24)18-15-33(23-9-12-27(34)28(35)19-23)13-16-37(17-14-33)31(40)32(2,3)4/h5-9,12,19,24-26H,10-11,13-18,20-21H2,1-4H3/t24-,25-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.24 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412740
(CHEMBL507098)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)c1ccccc1)c1ccc(Cl)c(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C35H38Cl2N4O/c1-24-38-32-9-5-6-10-33(32)41(24)29-22-27-12-13-28(23-29)40(27)20-17-35(26-11-14-30(36)31(37)21-26)15-18-39(19-16-35)34(42)25-7-3-2-4-8-25/h2-11,14,21,27-29H,12-13,15-20,22-23H2,1H3/t27-,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412741
(CHEMBL442933)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)C1CCCC1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C34H44N4O/c1-25-35-31-13-7-8-14-32(31)38(25)30-23-28-15-16-29(24-30)37(28)22-19-34(27-11-3-2-4-12-27)17-20-36(21-18-34)33(39)26-9-5-6-10-26/h2-4,7-8,11-14,26,28-30H,5-6,9-10,15-24H2,1H3/t28-,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412736
(CHEMBL499389)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1 |r,TLB:9:10:17:13.14,THB:18:17:10.11.16:13.14| Show InChI InChI=1S/C33H42Cl2N4O2/c1-22-36-29-7-5-6-8-30(29)39(22)26-20-24-10-11-25(21-26)38(24)18-15-33(23-9-12-27(34)28(35)19-23)13-16-37(17-14-33)31(40)41-32(2,3)4/h5-9,12,19,24-26H,10-11,13-18,20-21H2,1-4H3/t24-,25-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412739
(CHEMBL503033)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C35H40N4O/c1-26-36-32-14-8-9-15-33(32)39(26)31-24-29-16-17-30(25-31)38(29)23-20-35(28-12-6-3-7-13-28)18-21-37(22-19-35)34(40)27-10-4-2-5-11-27/h2-15,29-31H,16-25H2,1H3/t29-,30-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412742
(CHEMBL505270)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)OCc1ccccc1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C36H42N4O2/c1-27-37-33-14-8-9-15-34(33)40(27)32-24-30-16-17-31(25-32)39(30)23-20-36(29-12-6-3-7-13-29)18-21-38(22-19-36)35(41)42-26-28-10-4-2-5-11-28/h2-15,30-32H,16-26H2,1H3/t30-,31-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412743
(CHEMBL503915)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCC1(CCN(CC1)C(=O)OC(C)(C)C)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C33H44N4O2/c1-24-34-29-12-8-9-13-30(29)37(24)28-22-26-14-15-27(23-28)36(26)21-18-33(25-10-6-5-7-11-25)16-19-35(20-17-33)31(38)39-32(2,3)4/h5-13,26-28H,14-23H2,1-4H3/t26-,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412751
(CHEMBL522493)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CCN(C1)C(=O)c1ccco1 Show InChI InChI=1S/C31H34Cl2N4O3/c32-25-10-9-23(20-26(25)33)30(12-18-36(21-30)28(38)27-8-4-19-40-27)11-5-15-35-16-13-31(14-17-35)29(39)34-22-37(31)24-6-2-1-3-7-24/h1-4,6-10,19-20H,5,11-18,21-22H2,(H,34,39) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412749
(CHEMBL509298)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CCCN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C34H38Cl2N4O2/c35-29-14-13-27(23-30(29)36)33(16-8-20-39(24-33)31(41)26-9-3-1-4-10-26)15-7-19-38-21-17-34(18-22-38)32(42)37-25-40(34)28-11-5-2-6-12-28/h1-6,9-14,23H,7-8,15-22,24-25H2,(H,37,42) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412759
(CHEMBL491483)Show SMILES Cc1nc2ccccc2n1C1C[C@@H]2CC[C@@H](C1)N2CCC1(CCN(C1)C(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C32H40Cl2N4O2/c1-21-35-28-7-5-6-8-29(28)38(21)25-18-23-10-11-24(19-25)37(23)16-14-32(22-9-12-26(33)27(34)17-22)13-15-36(20-32)30(39)40-31(2,3)4/h5-9,12,17,23-25H,10-11,13-16,18-20H2,1-4H3/t23-,24-,32?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412766
(CHEMBL503631)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CCC(=O)N(Cc2ccccc2)C1 Show InChI InChI=1S/C34H38Cl2N4O2/c35-29-13-12-27(22-30(29)36)33(16-14-31(41)39(24-33)23-26-8-3-1-4-9-26)15-7-19-38-20-17-34(18-21-38)32(42)37-25-40(34)28-10-5-2-6-11-28/h1-6,8-13,22H,7,14-21,23-25H2,(H,37,42) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412770
(CHEMBL449125)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CN(Cc2ccccc2)C(=O)C1 Show InChI InChI=1S/C33H36Cl2N4O2/c34-28-13-12-26(20-29(28)35)32(21-30(40)38(23-32)22-25-8-3-1-4-9-25)14-7-17-37-18-15-33(16-19-37)31(41)36-24-39(33)27-10-5-2-6-11-27/h1-6,8-13,20H,7,14-19,21-24H2,(H,36,41) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412746
(CHEMBL446241)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCCC1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C36H42N4O/c1-27-37-33-15-8-9-16-34(33)40(27)32-25-30-17-18-31(26-32)39(30)22-10-19-36(29-13-6-3-7-14-29)20-23-38(24-21-36)35(41)28-11-4-2-5-12-28/h2-9,11-16,30-32H,10,17-26H2,1H3/t30-,31-/m1/s1 | PDB
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PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412754
(CHEMBL521699)Show SMILES Clc1ccc(cc1Cl)C1(CCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CCN(C1)C(=O)c1ccco1 Show InChI InChI=1S/C30H32Cl2N4O3/c31-24-9-8-22(19-25(24)32)29(11-17-35(20-29)27(37)26-7-4-18-39-26)10-14-34-15-12-30(13-16-34)28(38)33-21-36(30)23-5-2-1-3-6-23/h1-9,18-19H,10-17,20-21H2,(H,33,38) | PDB
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PubMed
| n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50070359
(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)CCCN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C33H36Cl2N4O2/c34-27-13-12-25(22-28(27)35)33(17-7-19-38(23-33)31(40)24-8-2-1-3-9-24)16-6-18-37-20-14-26(15-21-37)39-30-11-5-4-10-29(30)36-32(39)41/h1-5,8-13,22,26H,6-7,14-21,23H2,(H,36,41) | PDB
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| Article
PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412758
(CHEMBL448199)Show SMILES Clc1ccc(cc1Cl)C1(CCN(CC1)S(=O)(=O)c1ccccc1)OCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C32H36Cl2N4O4S/c33-28-12-11-25(23-29(28)34)32(15-19-37(20-16-32)43(40,41)27-9-5-2-6-10-27)42-22-21-36-17-13-31(14-18-36)30(39)35-24-38(31)26-7-3-1-4-8-26/h1-12,23H,13-22,24H2,(H,35,39) | PDB
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PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412763
(CHEMBL505556)Show SMILES Cc1nc2ccccc2n1C1CC2COCC(C1)N2CCC1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |TLB:9:10:13.14.15:18,19:18:13.14.15:17.10.11| Show InChI InChI=1S/C35H40N4O2/c1-26-36-32-14-8-9-15-33(32)39(26)29-22-30-24-41-25-31(23-29)38(30)21-18-35(28-12-6-3-7-13-28)16-19-37(20-17-35)34(40)27-10-4-2-5-11-27/h2-15,29-31H,16-25H2,1H3 | PDB
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PubMed
| n/a | n/a | >3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412761
(CHEMBL500523)Show SMILES Clc1ccc(cc1Cl)C1(CCN(CC1)C(=O)c1ccco1)OCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C31H34Cl2N4O4/c32-25-9-8-23(21-26(25)33)31(12-16-36(17-13-31)28(38)27-7-4-19-40-27)41-20-18-35-14-10-30(11-15-35)29(39)34-22-37(30)24-5-2-1-3-6-24/h1-9,19,21H,10-18,20,22H2,(H,34,39) | PDB
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PC sid
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Similars
| Article
PubMed
| n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412757
(CHEMBL522158)Show SMILES Clc1ccc(cc1Cl)C1(CCN(C1)C(=O)c1ccco1)OCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C30H32Cl2N4O4/c31-24-9-8-22(19-25(24)32)30(12-15-35(20-30)27(37)26-7-4-17-39-26)40-18-16-34-13-10-29(11-14-34)28(38)33-21-36(29)23-5-2-1-3-6-23/h1-9,17,19H,10-16,18,20-21H2,(H,33,38) | PDB
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PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412772
(CHEMBL492897)Show SMILES CC(C)(C)OC(=O)N1CCC(CCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)(CC1)c1ccccc1 Show InChI InChI=1S/C31H42N4O3/c1-30(2,3)38-29(37)34-22-17-31(18-23-34,24-10-5-4-6-11-24)16-9-19-33-20-14-25(15-21-33)35-27-13-8-7-12-26(27)32-28(35)36/h4-8,10-13,25H,9,14-23H2,1-3H3,(H,32,36) | PDB
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| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412744
(CHEMBL492292)Show SMILES CC(C)(C)OC(=O)N1CCC(CCN2CCC3(CC2)N(CNC3=O)c2ccccc2)(CC1)c1ccccc1 Show InChI InChI=1S/C31H42N4O3/c1-29(2,3)38-28(37)34-22-15-30(16-23-34,25-10-6-4-7-11-25)14-19-33-20-17-31(18-21-33)27(36)32-24-35(31)26-12-8-5-9-13-26/h4-13H,14-24H2,1-3H3,(H,32,36) | PDB
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PubMed
| n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412771
(CHEMBL521529)Show SMILES Clc1ccc(cc1Cl)C1(CCN(C1)C(=O)C1CCCC1)OCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C31H38Cl2N4O3/c32-26-11-10-24(20-27(26)33)31(14-17-36(21-31)28(38)23-6-4-5-7-23)40-19-18-35-15-12-30(13-16-35)29(39)34-22-37(30)25-8-2-1-3-9-25/h1-3,8-11,20,23H,4-7,12-19,21-22H2,(H,34,39) | PDB
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| n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412747
(CHEMBL503711)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCCC1(CCN(CC1)C(=O)c1ccco1)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C34H40N4O2/c1-25-35-30-11-5-6-12-31(30)38(25)29-23-27-14-15-28(24-29)37(27)19-8-16-34(26-9-3-2-4-10-26)17-20-36(21-18-34)33(39)32-13-7-22-40-32/h2-7,9-13,22,27-29H,8,14-21,23-24H2,1H3/t27-,28-/m1/s1 | PDB
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| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412750
(CHEMBL495297)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CCN(Cc2ccco2)C1 Show InChI InChI=1S/C31H36Cl2N4O2/c32-27-10-9-24(20-28(27)33)30(12-16-36(22-30)21-26-8-4-19-39-26)11-5-15-35-17-13-31(14-18-35)29(38)34-23-37(31)25-6-2-1-3-7-25/h1-4,6-10,19-20H,5,11-18,21-23H2,(H,34,38) | PDB
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Similars
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| n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412768
(CHEMBL444915)Show SMILES CN1CN(c2ccccc2)C2(CCN(CCCC3(CCN(C3)C(=O)c3ccco3)c3ccc(Cl)c(Cl)c3)CC2)C1=O Show InChI InChI=1S/C32H36Cl2N4O3/c1-35-23-38(25-7-3-2-4-8-25)32(30(35)40)14-17-36(18-15-32)16-6-12-31(24-10-11-26(33)27(34)21-24)13-19-37(22-31)29(39)28-9-5-20-41-28/h2-5,7-11,20-21H,6,12-19,22-23H2,1H3 | PDB
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Similars
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| n/a | n/a | 7.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412764
(CHEMBL492854)Show SMILES CC(C)(C)OC(=O)N1CCC(CCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C31H40Cl2N4O3/c1-30(2,3)40-29(39)36-19-14-31(15-20-36,22-9-10-24(32)25(33)21-22)13-6-16-35-17-11-23(12-18-35)37-27-8-5-4-7-26(27)34-28(37)38/h4-5,7-10,21,23H,6,11-20H2,1-3H3,(H,34,38) | PDB
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| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412745
(CHEMBL524159)Show SMILES CC(C)(C)OC(=O)N1CCC(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)(CC1)c1ccccc1 Show InChI InChI=1S/C32H44N4O3/c1-30(2,3)39-29(38)35-23-16-31(17-24-35,26-11-6-4-7-12-26)15-10-20-34-21-18-32(19-22-34)28(37)33-25-36(32)27-13-8-5-9-14-27/h4-9,11-14H,10,15-25H2,1-3H3,(H,33,37) | PDB
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PC sid
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Similars
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PubMed
| n/a | n/a | 8.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412760
(CHEMBL501077)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CN(C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C31H34Cl2N4O3S/c32-27-13-12-24(20-28(27)33)30(21-36(22-30)41(39,40)26-10-5-2-6-11-26)14-7-17-35-18-15-31(16-19-35)29(38)34-23-37(31)25-8-3-1-4-9-25/h1-6,8-13,20H,7,14-19,21-23H2,(H,34,38) | PDB
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PC sid
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| Article
PubMed
| n/a | n/a | 9.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412755
(CHEMBL495291)Show SMILES Clc1ccc(cc1Cl)C1(CCN2CCC3(CC2)N(CNC3=O)c2ccccc2)CN(Cc2ccccc2)C(=O)C1 Show InChI InChI=1S/C32H34Cl2N4O2/c33-27-12-11-25(19-28(27)34)31(20-29(39)37(22-31)21-24-7-3-1-4-8-24)13-16-36-17-14-32(15-18-36)30(40)35-23-38(32)26-9-5-2-6-10-26/h1-12,19H,13-18,20-23H2,(H,35,40) | PDB
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Similars
| Article
PubMed
| n/a | n/a | 9.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412753
(CHEMBL495298)Show SMILES O=C(N1CCC(CCN2CCC3(CC2)N(CNC3=O)c2ccccc2)(C1)c1ccccc1)c1ccco1 Show InChI InChI=1S/C30H34N4O3/c35-27(26-12-7-21-37-26)33-20-14-29(22-33,24-8-3-1-4-9-24)13-17-32-18-15-30(16-19-32)28(36)31-23-34(30)25-10-5-2-6-11-25/h1-12,21H,13-20,22-23H2,(H,31,36) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50070353
(1-(1-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-pi...)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)CCC(=O)N(Cc2ccccc2)C1 Show InChI InChI=1S/C33H36Cl2N4O2/c34-27-12-11-25(21-28(27)35)33(17-13-31(40)38(23-33)22-24-7-2-1-3-8-24)16-6-18-37-19-14-26(15-20-37)39-30-10-5-4-9-29(30)36-32(39)41/h1-5,7-12,21,26H,6,13-20,22-23H2,(H,36,41) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412765
(CHEMBL453404)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCCC1(CCN(CC1)C(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C34H44Cl2N4O2/c1-23-37-30-8-5-6-9-31(30)40(23)27-21-25-11-12-26(22-27)39(25)17-7-14-34(24-10-13-28(35)29(36)20-24)15-18-38(19-16-34)32(41)42-33(2,3)4/h5-6,8-10,13,20,25-27H,7,11-12,14-19,21-22H2,1-4H3/t25-,26-/m1/s1 | PDB
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UniProtKB/SwissProt
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412756
(CHEMBL502593)Show SMILES Clc1ccc(cc1Cl)C1(CCN(C1)S(=O)(=O)c1ccccc1)OCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C31H34Cl2N4O4S/c32-27-12-11-24(21-28(27)33)31(15-18-36(22-31)42(39,40)26-9-5-2-6-10-26)41-20-19-35-16-13-30(14-17-35)29(38)34-23-37(30)25-7-3-1-4-8-25/h1-12,21H,13-20,22-23H2,(H,34,38) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412767
(CHEMBL454841)Show SMILES NC(=O)C1(CCN(CCCC2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)Nc1ccccc1 Show InChI InChI=1S/C33H38Cl2N4O2/c34-28-14-13-26(23-29(28)35)32(16-8-20-39(24-32)30(40)25-9-3-1-4-10-25)15-7-19-38-21-17-33(18-22-38,31(36)41)37-27-11-5-2-6-12-27/h1-6,9-14,23,37H,7-8,15-22,24H2,(H2,36,41) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412769
(CHEMBL493884)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(CNC3=O)C2CCCCC2)CCN(C1)C(=O)c1ccco1 Show InChI InChI=1S/C31H40Cl2N4O3/c32-25-10-9-23(20-26(25)33)30(12-18-36(21-30)28(38)27-8-4-19-40-27)11-5-15-35-16-13-31(14-17-35)29(39)34-22-37(31)24-6-2-1-3-7-24/h4,8-10,19-20,24H,1-3,5-7,11-18,21-22H2,(H,34,39) | PDB
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| Article
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| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412748
(CHEMBL473584)Show SMILES Cc1nc2ccccc2n1C1C[C@H]2CC[C@H](C1)N2CCCC1(CCN(CC1)C(=O)OC(C)(C)C)c1ccccc1 |r,TLB:9:10:17:13.14| Show InChI InChI=1S/C34H46N4O2/c1-25-35-30-13-8-9-14-31(30)38(25)29-23-27-15-16-28(24-29)37(27)20-10-17-34(26-11-6-5-7-12-26)18-21-36(22-19-34)32(39)40-33(2,3)4/h5-9,11-14,27-29H,10,15-24H2,1-4H3/t27-,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
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PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50412752
(CHEMBL507223)Show SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CC2)N(C(=O)NC3=O)c2ccccc2)CCN(C1)C(=O)c1ccco1 Show InChI InChI=1S/C31H32Cl2N4O4/c32-24-10-9-22(20-25(24)33)30(12-18-36(21-30)27(38)26-8-4-19-41-26)11-5-15-35-16-13-31(14-17-35)28(39)34-29(40)37(31)23-6-2-1-3-7-23/h1-4,6-10,19-20H,5,11-18,21H2,(H,34,39,40) | PDB
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PC cid
PC sid
UniChem
Similars
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PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cells |
J Med Chem 51: 6538-46 (2008)
Article DOI: 10.1021/jm800598a
BindingDB Entry DOI: 10.7270/Q2WS8VG8 |
More data for this
Ligand-Target Pair | |
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