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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27633 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27634 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27628 (5-bromo-N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27627 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27637 (N-{3-[(1S)-1-[(5-bromopyridin-3-yl)amino]ethyl]phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27631 (3-chloro-N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27632 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27630 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27639 (N-{3-[(1S)-1-{[6-(4-hydroxy-3-methoxyphenyl)pyrazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27626 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27619 (N-[3-(1-{[6-(4-hydroxy-3-methoxyphenyl)pyrazin-2-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27625 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27629 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27640 (N-{3-[(1R)-1-{[6-(4-hydroxy-3-methoxyphenyl)pyrazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 416 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27620 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 857 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27635 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27624 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27623 (6-chloro-N-[(1S)-1-{3-[(pyridin-3-ylmethyl)amino]p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27636 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27638 (N-{3-[(1S)-1-[(6-bromopyridin-2-yl)amino]ethyl]phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27621 (N-[(1S)-1-(3-aminophenyl)ethyl]-6-chloropyrazin-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM27622 (N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Cytopia Research Pty Ltd | Assay Description Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures... | Bioorg Med Chem Lett 19: 1206-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.073 BindingDB Entry DOI: 10.7270/Q2PZ5742 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
