Affinity Data by PubMed id=19168362

PubMed code 19168362

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276678 (3-(4,5,6,7-Tetrabromo-1H-1,2,3-benzotriazol-1-yl)p...) Show SMILES OCCCn1nnc2c(Br)c(Br)c(Br)c(Br)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276679 (3-(4,5,6,7-Tetrabromo-2H-1,2,3-benzotriazol-2-yl)p...) Show SMILES OCCCn1nc2c(Br)c(Br)c(Br)c(Br)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM11323 (4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole \| 4,5,6,...) Show SMILES Brc1c(Br)c(Br)c2[nH]nnc2c1Br Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276732 (3-(4,5,6,7-Tetrabromo-1H-benzimidazol-1-yl)propan-...) Show SMILES OCCCn1cnc2c(Br)c(Br)c(Br)c(Br)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50156669 (4,5,6,7-TETRABROMO-BENZIMIDAZOLE \| 4,5,6,7-tetrabr...) Show SMILES Brc1c(Br)c(Br)c2[nH]cnc2c1Br Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276731 (4-(4,5,6,7-tetrabromo-2H-1,2,3-benzotriazol-2-yl)b...) Show SMILES OCCCCn1nc2c(Br)c(Br)c(Br)c(Br)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276680 (3-(4,5,6,7-Tetrabromo-2H-1,2,3-benzotriazol-2-yl)p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276733 (1-(3-chloropropyl)-4,5,6,7-tetrabromo-1H-benzimida...) Show SMILES ClCCCn1cnc2c(Br)c(Br)c(Br)c(Br)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276730 (4,5,6,7-Tetrabromo-2-[3-(4-methylpiperazin-1-yl)pr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276630 (2-(perbromo-1H-benzo[d][1,2,3]triazol-1-yl)ethanol...) Show SMILES OCCn1nnc2c(Br)c(Br)c(Br)c(Br)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50276682 (4,5,6,7-Tetrabromo-1-[3-(4-methylpiperazin-1-yl)pr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%