Affinity Data by PubMed id=19853441

PubMed code 19853441

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299749 ((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM18355 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM18355 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299749 ((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299750 ((1S,3R,4S,5R,6R,7S)-4,5-Dihydroxy-3-(hydroxymethyl...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299753 (CHEMBL584580 \| N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydrox...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299752 ((1S,3R,4S,5R,6R,7S)-4,5-dihydroxy-3-(hydroxymethyl...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299751 ((1S,3R,4S,5R,6R,7S)-N-butyl-4,5-dihydroxy-3-(hydro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299751 ((1S,3R,4S,5R,6R,7S)-N-butyl-4,5-dihydroxy-3-(hydro...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299750 ((1S,3R,4S,5R,6R,7S)-4,5-Dihydroxy-3-(hydroxymethyl...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299754 (CHEMBL577370 \| N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydrox...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299752 ((1S,3R,4S,5R,6R,7S)-4,5-dihydroxy-3-(hydroxymethyl...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50299753 (CHEMBL584580 \| N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydrox...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha glucosidase				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50299754 (CHEMBL577370 \| N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydrox...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human GBA2				Bioorg Med Chem Lett 19: 6600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.10.022 BindingDB Entry DOI: 10.7270/Q2736QZB
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%