Affinity Data by PubMed id=20005103

PubMed code 20005103

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305900 ((+)-2-((1S,5S,6R)-6-(aminomethyl)bicyclo[3.2.0]hep...) Show SMILES NC[C@@]1(CC(O)=O)C[C@@H]2CCC[C@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305887 (3,4-trans-2-(1-(aminomethyl)-3,4-dimethylcyclopent...) Show SMILES C[C@H]1CC(CN)(CC(O)=O)C[C@@H]1C \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305894 ((+/-)-2-((6S)-6-(aminomethyl)bicyclo[3.2.0]heptan-...) Show SMILES NC[C@]1(CC(O)=O)CC2CCCC12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305885 (CHEMBL595172 \| cis-2-((1R,5S)-3-(aminomethyl)bicyc...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305899 ((-)-2-((1R,5R,6S)-6-(aminomethyl)bicyclo[3.2.0]hep...) Show SMILES NC[C@]1(CC(O)=O)C[C@H]2CCC[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305886 (2-((3R,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl...) Show SMILES C[C@H]1C[C@](CN)(CC(O)=O)C[C@H]1C \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305884 (CHEMBL609569 \| cis-2-((1R,5S)-3-(aminomethyl)bicyc...) Show SMILES NC[C@]1(CC(O)=O)C[C@@H]2CC[C@@H]2C1 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305897 ((+/-)-2-((7S)-7-(aminomethyl)bicyclo[4.2.0]octan-7...) Show SMILES NC[C@]1(CC(O)=O)CC2CCCCC12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305892 (2-((2R,3aR)-2-(aminomethyl)octahydro-1H-inden-2-yl...) Show SMILES NC[C@]1(CC(O)=O)C[C@H]2CCCC[C@H]2C1 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305890 (2-((2R,3aR)-2-(aminomethyl)octahydropentalen-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305895 ((+/-)-2-((6R)-6-(aminomethyl)bicyclo[3.2.0]heptan-...) Show SMILES NC[C@@]1(CC(O)=O)CC2CCCC12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305884 (CHEMBL609569 \| cis-2-((1R,5S)-3-(aminomethyl)bicyc...) Show SMILES NC[C@]1(CC(O)=O)C[C@@H]2CC[C@@H]2C1 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305898 ((+/-)-2-((7R)-7-(aminomethyl)bicyclo[4.2.0]octan-7...) Show SMILES NC[C@@]1(CC(O)=O)CC2CCCCC12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305896 ((+/-)-2-((1S)-1-(aminomethyl)octahydropentalen-1-y...) Show SMILES NC[C@]1(CC(O)=O)CCC2CCCC12 \|r\| Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305889 ((+/-)-2-(2-(aminomethyl)octahydro-1H-inden-2-yl)ac...) Show SMILES NCC1(CC(O)=O)CC2CCCCC2C1 Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305891 (2-((2S,3aR)-2-(aminomethyl)octahydropentalen-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305888 ((+/-)-2-(2-(aminomethyl)octahydropentalen-2-yl)ace...) Show SMILES NCC1(CC(O)=O)CC2CCCC2C1 Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305893 (2-((2S,3aR)-2-(aminomethyl)octahydro-1H-inden-2-yl...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%