Affinity Data by PubMed id=2002476

PubMed code 2002476

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidylate synthase (Mus musculus)	BDBM50011751 (2-{4-[(2-Amino-4-thioxo-3,4-dihydro-quinazolin-6-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Growth inhibition of thymidylate synthase(TS) in L1210 cells				J Med Chem 34: 978-84 (1991) BindingDB Entry DOI: 10.7270/Q2VD6XDB
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50011752 (2-{4-[(2-Methyl-4-thioxo-3,4-dihydro-quinazolin-6-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Growth inhibition of thymidylate synthase(TS) in L1210 cells				J Med Chem 34: 978-84 (1991) BindingDB Entry DOI: 10.7270/Q2VD6XDB
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50011753 (2-{4-[Prop-2-ynyl-(4-thioxo-3,4-dihydro-quinazolin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Growth inhibition of thymidylate synthase(TS) in L1210 cells				J Med Chem 34: 978-84 (1991) BindingDB Entry DOI: 10.7270/Q2VD6XDB
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50011754 (2-{4-[Ethyl-(4-thioxo-3,4-dihydro-quinazolin-6-ylm...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Growth inhibition of thymidylate synthase(TS) in L1210 cells				J Med Chem 34: 978-84 (1991) BindingDB Entry DOI: 10.7270/Q2VD6XDB
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50011750 (2-{4-[Ethyl-(4-methylsulfanyl-quinazolin-6-ylmethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Growth inhibition of thymidylate synthase(TS) in L1210 cells				J Med Chem 34: 978-84 (1991) BindingDB Entry DOI: 10.7270/Q2VD6XDB
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%