BindingDB logo
myBDB logout

PubMed code 20356098

Compile data set for download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50298281
PNG
(CHEMBL1091036 | N-(4-Amino-2,6-diisopropylphenyl)-...)
Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCCO
Show InChI InChI=1S/C35H48N4O4/c1-24(2)29-21-27(36)22-30(25(3)4)33(29)38-34(41)37-23-35(26-10-8-11-28(20-26)42-5)14-16-39(17-15-35)31-12-6-7-13-32(31)43-19-9-18-40/h6-8,10-13,20-22,24-25,40H,9,14-19,23,36H2,1-5H3,(H2,37,38,41)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316168
PNG
(2,6-Diisopropylphenyl{[1-(2-Methoxyphenyl)-4-(3-me...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C32H40N2O6S/c1-22(2)26-13-10-14-27(23(3)4)30(26)40-41(36,37)33-31(35)32(24-11-9-12-25(21-24)38-5)17-19-34(20-18-32)28-15-7-8-16-29(28)39-6/h7-16,21-23H,17-20H2,1-6H3,(H,33,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316169
PNG
(2,6-Dimethylphenyl{[1-(2-Methoxyphenyl)-4-(3-metho...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Oc1c(C)cccc1C
Show InChI InChI=1S/C28H32N2O6S/c1-20-9-7-10-21(2)26(20)36-37(32,33)29-27(31)28(22-11-8-12-23(19-22)34-3)15-17-30(18-16-28)24-13-5-6-14-25(24)35-4/h5-14,19H,15-18H2,1-4H3,(H,29,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316156
PNG
(2,6-Diisopropylphenyl{[1-(5-Bromopyrimidin-2-yl)-4...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ncc(Br)cn1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C29H35BrN4O5S/c1-19(2)24-10-7-11-25(20(3)4)26(24)39-40(36,37)33-27(35)29(21-8-6-9-23(16-21)38-5)12-14-34(15-13-29)28-31-17-22(30)18-32-28/h6-11,16-20H,12-15H2,1-5H3,(H,33,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316157
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-(5-pr...)
Show SMILES CCCc1cnc(nc1)N1CCC(CC1)(C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C)c1cccc(OC)c1
Show InChI InChI=1S/C32H42N4O5S/c1-7-10-24-20-33-31(34-21-24)36-17-15-32(16-18-36,25-11-8-12-26(19-25)40-6)30(37)35-42(38,39)41-29-27(22(2)3)13-9-14-28(29)23(4)5/h8-9,11-14,19-23H,7,10,15-18H2,1-6H3,(H,35,37)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316159
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-(4-me...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1nccc(C)n1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C30H38N4O5S/c1-20(2)25-11-8-12-26(21(3)4)27(25)39-40(36,37)33-28(35)30(23-9-7-10-24(19-23)38-6)14-17-34(18-15-30)29-31-16-13-22(5)32-29/h7-13,16,19-21H,14-15,17-18H2,1-6H3,(H,33,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316162
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-(3-me...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ncccc1OC)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C31H39N3O6S/c1-21(2)25-12-8-13-26(22(3)4)28(25)40-41(36,37)33-30(35)31(23-10-7-11-24(20-23)38-5)15-18-34(19-16-31)29-27(39-6)14-9-17-32-29/h7-14,17,20-22H,15-16,18-19H2,1-6H3,(H,33,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316166
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-methy...)
Show SMILES COc1cccc(c1)C1(CCN(C)CC1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C26H36N2O5S/c1-18(2)22-11-8-12-23(19(3)4)24(22)33-34(30,31)27-25(29)26(13-15-28(5)16-14-26)20-9-7-10-21(17-20)32-6/h7-12,17-19H,13-16H2,1-6H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316170
PNG
(2-Cyclopentylphenyl{[1-(2-Methoxyphenyl)-4-(3-meth...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Oc1ccccc1C1CCCC1
Show InChI InChI=1S/C31H36N2O6S/c1-37-25-13-9-12-24(22-25)31(18-20-33(21-19-31)27-15-6-8-17-29(27)38-2)30(34)32-40(35,36)39-28-16-7-5-14-26(28)23-10-3-4-11-23/h5-9,12-17,22-23H,3-4,10-11,18-21H2,1-2H3,(H,32,34)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316161
PNG
(2,6-Diisopropylphenyl{[1-(1,3-Benzothiazol-2-yl)-4...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1nc2ccccc2s1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C32H37N3O5S2/c1-21(2)25-12-9-13-26(22(3)4)29(25)40-42(37,38)34-30(36)32(23-10-8-11-24(20-23)39-5)16-18-35(19-17-32)31-33-27-14-6-7-15-28(27)41-31/h6-15,20-22H,16-19H2,1-5H3,(H,34,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316167
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)Piperidi...)
Show SMILES COc1cccc(c1)C1(CCNCC1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C25H34N2O5S/c1-17(2)21-10-7-11-22(18(3)4)23(21)32-33(29,30)27-24(28)25(12-14-26-15-13-25)19-8-6-9-20(16-19)31-5/h6-11,16-18,26H,12-15H2,1-5H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316171
PNG
(2-Propylphenyl{[1-(2-Methoxyphenyl)-4-(3-methoxyph...)
Show SMILES CCCc1ccccc1OS(=O)(=O)NC(=O)C1(CCN(CC1)c1ccccc1OC)c1cccc(OC)c1
Show InChI InChI=1S/C29H34N2O6S/c1-4-10-22-11-5-7-15-26(22)37-38(33,34)30-28(32)29(23-12-9-13-24(21-23)35-2)17-19-31(20-18-29)25-14-6-8-16-27(25)36-3/h5-9,11-16,21H,4,10,17-20H2,1-3H3,(H,30,32)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316177
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-pyrim...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ncccn1)C(=O)N(C)S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C30H38N4O5S/c1-21(2)25-12-8-13-26(22(3)4)27(25)39-40(36,37)33(5)28(35)30(23-10-7-11-24(20-23)38-6)14-18-34(19-15-30)29-31-16-9-17-32-29/h7-13,16-17,20-22H,14-15,18-19H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316165
PNG
(2,6-Diisopropylphenyl{[1-Acetyl-4-(3-methoxyphenyl...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)C(C)=O)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C27H36N2O6S/c1-18(2)23-11-8-12-24(19(3)4)25(23)35-36(32,33)28-26(31)27(13-15-29(16-14-27)20(5)30)21-9-7-10-22(17-21)34-6/h7-12,17-19H,13-16H2,1-6H3,(H,28,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316173
PNG
(CHEMBL1093917 | Phenyl{[1-(2-Methoxyphenyl)-4-(3-m...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Oc1ccccc1
Show InChI InChI=1S/C26H28N2O6S/c1-32-22-12-8-9-20(19-22)26(25(29)27-35(30,31)34-21-10-4-3-5-11-21)15-17-28(18-16-26)23-13-6-7-14-24(23)33-2/h3-14,19H,15-18H2,1-2H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316174
PNG
(CHEMBL1090605 | N-{[(2,6-Diisopropylphenyl)amino]s...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Nc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C32H41N3O5S/c1-22(2)26-13-10-14-27(23(3)4)30(26)33-41(37,38)34-31(36)32(24-11-9-12-25(21-24)39-5)17-19-35(20-18-32)28-15-7-8-16-29(28)40-6/h7-16,21-23,33H,17-20H2,1-6H3,(H,34,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316175
PNG
(CHEMBL1095560 | N-(2,6-Diisopropylphenyl)-1-(2-met...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)Nc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C32H40N2O3/c1-22(2)26-13-10-14-27(23(3)4)30(26)33-31(35)32(24-11-9-12-25(21-24)36-5)17-19-34(20-18-32)28-15-7-8-16-29(28)37-6/h7-16,21-23H,17-20H2,1-6H3,(H,33,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316164
PNG
(2,6-Diisopropylphenyl{[1-Benzoyl-4-(3-methoxypheny...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)C(=O)c1ccccc1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C32H38N2O6S/c1-22(2)27-15-10-16-28(23(3)4)29(27)40-41(37,38)33-31(36)32(25-13-9-14-26(21-25)39-5)17-19-34(20-18-32)30(35)24-11-7-6-8-12-24/h6-16,21-23H,17-20H2,1-5H3,(H,33,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316158
PNG
(2,6-Diisopropylphenyl({4-(3-Methoxyphenyl)-1-[4-(t...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1nccc(n1)C(F)(F)F)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C30H35F3N4O5S/c1-19(2)23-10-7-11-24(20(3)4)26(23)42-43(39,40)36-27(38)29(21-8-6-9-22(18-21)41-5)13-16-37(17-14-29)28-34-15-12-25(35-28)30(31,32)33/h6-12,15,18-20H,13-14,16-17H2,1-5H3,(H,36,38)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316163
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-pheny...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C31H38N2O5S/c1-22(2)27-15-10-16-28(23(3)4)29(27)38-39(35,36)32-30(34)31(24-11-9-14-26(21-24)37-5)17-19-33(20-18-31)25-12-7-6-8-13-25/h6-16,21-23H,17-20H2,1-5H3,(H,32,34)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316160
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-pyrim...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ncccn1)C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C29H36N4O5S/c1-20(2)24-11-7-12-25(21(3)4)26(24)38-39(35,36)32-27(34)29(22-9-6-10-23(19-22)37-5)13-17-33(18-14-29)28-30-15-8-16-31-28/h6-12,15-16,19-21H,13-14,17-18H2,1-5H3,(H,32,34)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50316172
PNG
(2-Methylphenyl{[1-(2-Methoxyphenyl)-4-(3-methoxyph...)
Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ccccc1OC)C(=O)NS(=O)(=O)Oc1ccccc1C
Show InChI InChI=1S/C27H30N2O6S/c1-20-9-4-6-13-24(20)35-36(31,32)28-26(30)27(21-10-8-11-22(19-21)33-2)15-17-29(18-16-27)23-12-5-7-14-25(23)34-3/h4-14,19H,15-18H2,1-3H3,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50175765
PNG
(1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...)
Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O
Show InChI InChI=1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT

J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%