Affinity Data by PubMed id=20409708

PubMed code 20409708

Found 65 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318312 ((R)-5-hexyl-3-phenyloxazolidin-2-one \| CHEMBL10947...) Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318323 (3-(4-chlorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318325 (3-(5-hexyl-2-oxo-1,3-oxazolidin-3-yl)benzonitrile ...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(c1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318335 (3-(4-aminophenyl)-5-hexyloxazolidin-2-one \| CHEMBL...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(N)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318338 (CHEMBL1094462 \| methyl 4-(5-hexyl-2-oxooxazolidin-...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(cc1)C(=O)OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318345 (5-benzyl-3-phenyloxazolidin-2-one \| CHEMBL1095704) Show SMILES O=C1OC(Cc2ccccc2)CN1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318362 (5-((2-chlorophenoxy)methyl)-3-phenyloxazolidin-2-o...) Show SMILES Clc1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318308 (4-((2-oxo-3-phenyloxazolidin-5-yl)methoxy)benzamid...) Show SMILES NC(=O)c1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318309 (CHEMBL1096052 \| N-(2-((2-oxo-3-phenyloxazolidin-5-...) Show SMILES CC(=O)Nc1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318318 (3-(2-fluorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.15E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318320 (3-(4-fluorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318331 (5-hexyl-3-(3-hydroxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318334 (3-(3-aminophenyl)-5-hexyloxazolidin-2-one \| CHEMBL...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(N)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318340 (5-hexyl-3-(3-(methylsulfonyl)phenyl)oxazolidin-2-o...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(c1)S(C)(=O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318343 (5-pentyl-3-phenyloxazolidin-2-one \| CHEMBL1095702) Show SMILES CCCCCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318351 (5-((2-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...) Show SMILES CCc1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318353 (5-((4-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...) Show SMILES CCc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318365 (3-phenyl-5-((3-(trifluoromethyl)phenoxy)methyl)oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318312 ((R)-5-hexyl-3-phenyloxazolidin-2-one \| CHEMBL10947...) Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318316 (5-hexyl-3-m-tolyloxazolidin-2-one \| CHEMBL1096423) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(C)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318321 (3-(2-chlorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1Cl Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318322 (3-(3-chlorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318336 (CHEMBL1094125 \| methyl 2-(5-hexyl-2-oxooxazolidin-...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1C(=O)OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318341 (5-hexyl-3-(4-(methylsulfonyl)phenyl)oxazolidin-2-o...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(cc1)S(C)(=O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318357 (5-((3-tert-butylphenoxy)methyl)-3-phenyloxazolidin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318364 (3-phenyl-5-((2-(trifluoromethyl)phenoxy)methyl)oxa...) Show SMILES FC(F)(F)c1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318368 (5-((4-aminophenoxy)methyl)-3-phenyloxazolidin-2-on...) Show SMILES Nc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318313 (3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318327 (5-hexyl-3-(2-methoxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318329 (5-hexyl-3-(4-methoxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318332 (5-hexyl-3-(4-hydroxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.81E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318344 (5-butyl-3-phenyloxazolidin-2-one \| CHEMBL1095703) Show SMILES CCCCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318346 (5-(phenoxymethyl)-3-phenyloxazolidin-2-one \| CHEMB...) Show SMILES O=C1OC(COc2ccccc2)CN1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318347 (5-((4-chlorophenoxy)methyl)-3-phenyloxazolidin-2-o...) Show SMILES Clc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318349 (3-phenyl-5-(m-tolyloxymethyl)oxazolidin-2-one \| CH...) Show SMILES Cc1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318356 (5-((4-isopropylphenoxy)methyl)-3-phenyloxazolidin-...) Show SMILES CC(C)c1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318358 (5-[(4-tert-butylphenoxy)methyl]-3-phenyl-1,3-oxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318359 (5-((2-methoxyphenoxy)methyl)-3-phenyloxazolidin-2-...) Show SMILES COc1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318317 (5-hexyl-3-p-tolyloxazolidin-2-one \| CHEMBL1095638) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(C)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318319 (3-(3-fluorophenyl)-5-hexyloxazolidin-2-one \| CHEMB...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318339 (5-hexyl-3-(2-(methylsulfonyl)phenyl)oxazolidin-2-o...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1S(C)(=O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318360 (5-((3-methoxyphenoxy)methyl)-3-phenyloxazolidin-2-...) Show SMILES COc1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.11E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318311 (CHEMBL1094430 \| N-(4-((2-oxo-3-phenyloxazolidin-5-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318313 (3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318314 ((R)-3-(5-((4-tert-butylphenoxy)methyl)-2-oxooxazol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318315 (5-hexyl-3-o-tolyloxazolidin-2-one \| CHEMBL1096081) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318326 (4-(5-hexyl-2-oxooxazolidin-3-yl)benzonitrile \| CHE...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccc(cc1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318328 (5-hexyl-3-(3-methoxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(OC)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318312 ((R)-5-hexyl-3-phenyloxazolidin-2-one \| CHEMBL10947...) Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318342 (5-octyl-3-phenyloxazolidin-2-one \| CHEMBL1095701) Show SMILES CCCCCCCCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318350 (3-phenyl-5-(p-tolyloxymethyl)oxazolidin-2-one \| CH...) Show SMILES Cc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318363 (5-((3-chlorophenoxy)methyl)-3-phenyloxazolidin-2-o...) Show SMILES Clc1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318366 (3-phenyl-5-((4-(trifluoromethyl)phenoxy)methyl)oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318367 (5-((3-aminophenoxy)methyl)-3-phenyloxazolidin-2-on...) Show SMILES Nc1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318369 (3-((2-oxo-3-phenyloxazolidin-5-yl)methoxy)benzamid...) Show SMILES NC(=O)c1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318337 (CHEMBL1094461 \| methyl 3-(5-hexyl-2-oxooxazolidin-...) Show SMILES CCCCCCC1CN(C(=O)O1)c1cccc(c1)C(=O)OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318348 (3-phenyl-5-(o-tolyloxymethyl)oxazolidin-2-one \| CH...) Show SMILES Cc1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318355 (5-((3-isopropylphenoxy)methyl)-3-phenyloxazolidin-...) Show SMILES CC(C)c1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318361 (5-((4-methoxyphenoxy)methyl)-3-phenyloxazolidin-2-...) Show SMILES COc1ccc(OCC2CN(C(=O)O2)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318310 (CHEMBL1094429 \| N-(3-((2-oxo-3-phenyloxazolidin-5-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318324 (2-(5-hexyl-2-oxooxazolidin-3-yl)benzonitrile \| CHE...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318330 (5-hexyl-3-(2-hydroxyphenyl)oxazolidin-2-one \| CHEM...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318333 (3-(2-aminophenyl)-5-hexyloxazolidin-2-one \| CHEMBL...) Show SMILES CCCCCCC1CN(C(=O)O1)c1ccccc1N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318352 (5-((3-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...) Show SMILES CCc1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318354 (5-((2-isopropylphenoxy)methyl)-3-phenyloxazolidin-...) Show SMILES CC(C)c1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%