Affinity Data by PubMed id=20568732

PubMed code 20568732

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346585 (CHEMBL1795980 \| S2101) Show SMILES NC1CC1c1cc(F)cc(F)c1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346868 (CHEMBL1797645 \| S2111) Show SMILES CCc1cccc(COc2c(F)cc(F)cc2C2CC2N)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92885 (S2107) Show SMILES NCc1cccc(COc2c(F)cc(F)cc2C2CC2N)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346866 (CHEMBL1797643 \| S1201) Show SMILES NC1CC1c1cccc(F)c1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346865 (2-PFPA \| CHEMBL1797642) Show SMILES NC1CC1c1c(F)c(F)c(F)c(F)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346867 (CHEMBL1797644 \| S1402) Show SMILES CC(C)COc1ccc(Cl)cc1C1CC1N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92886 (S2206) Show SMILES COc1cccc(COc2c(F)cc(F)cc2C2CC2N)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92880 (S1401) Show SMILES NC1CC1c1cc(Cl)ccc1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92882 (S1601) Show SMILES NC1CC1c1ccc(OCc2ccccc2)cc1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92883 (S1602) Show SMILES CC(C)COc1ccc(C2CC2N)c(OCC(C)C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92884 (S1603) Show SMILES NC1CC1c1ccc(OCC2CCCCC2)cc1OCC1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92879 (S1310) Show SMILES NC1CC1c1cc(F)ccc1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM92881 (S1502) Show SMILES CC(C)COc1c(Cl)cc(Cl)cc1C1CC1N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50113851 ((+/-)-Tranylcypromine \| 2-PCPA \| 2-Phenyl-cyclopro...) Show SMILES NC1CC1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Systems and Structural Biology Center					Assay Description The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.				Biochemistry 49: 6494-503 (2010) Article DOI: 10.1021/bi100299r BindingDB Entry DOI: 10.7270/Q2PK0DSZ
RIKEN Systems and Structural Biology Center					More data for this Ligand-Target Pair

* indicates data uncertainty>20%