Affinity Data by PubMed id=20580561

PubMed code 20580561

Found 33 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326674 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326678 (4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326680 (4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326674 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326676 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11635 (4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM11635 (4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM11635 (4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326676 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326680 (4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326675 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326678 (4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326675 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326679 (4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326677 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326674 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326680 (4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326675 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326678 (4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326677 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326677 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326676 (4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326679 (4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326679 (4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydrofolate reductase (Lactobacillus casei)	BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydrofolate reductase (Lactobacillus casei)	BDBM50326679 (4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydrofolate reductase (Lactobacillus casei)	BDBM50326680 (4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydrofolate reductase (Lactobacillus casei)	BDBM50326675 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydrofolate reductase (Lactobacillus casei)	BDBM50326674 (4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydrofolate reductase (Lactobacillus casei)	BDBM50326678 (4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Superior T£cnico Curated by ChEMBL					Assay Description Inhibition of Lactobacillus casei DHFR by spectrophotometric analysis				Bioorg Med Chem 18: 5081-9 (2010) Article DOI: 10.1016/j.bmc.2010.05.072 BindingDB Entry DOI: 10.7270/Q2T154M1
Instituto Superior T£cnico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)

* indicates data uncertainty>20%