Affinity Data by PubMed id=20716489

PubMed code 20716489

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50005677 (CHEMBL23957 \| OXO-M \| Trimethyl-[4-(2-oxo-pyrrolid...) Show SMILES C[N+](C)(C)CC#CCN1CCCC1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50336544 ((+)-Muscarine chloride \| CHEMBL1255785 \| muscarine...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide \| 2-acet...) Show SMILES CC(=O)OCC[N+](C)(C)C Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50005677 (CHEMBL23957 \| OXO-M \| Trimethyl-[4-(2-oxo-pyrrolid...) Show SMILES C[N+](C)(C)CC#CCN1CCCC1=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide \| 2-acet...) Show SMILES CC(=O)OCC[N+](C)(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide \| 2-acet...) Show SMILES CC(=O)OCC[N+](C)(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50005677 (CHEMBL23957 \| OXO-M \| Trimethyl-[4-(2-oxo-pyrrolid...) Show SMILES C[N+](C)(C)CC#CCN1CCCC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50336544 ((+)-Muscarine chloride \| CHEMBL1255785 \| muscarine...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50336544 ((+)-Muscarine chloride \| CHEMBL1255785 \| muscarine...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal				Bioorg Med Chem 19: 1048-54 (2011) Article DOI: 10.1016/j.bmc.2010.07.060 BindingDB Entry DOI: 10.7270/Q2SF2WFK
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%