Affinity Data by PubMed id=20843696

PubMed code 20843696

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50327102 (4'-Butoxy-2,6-difluoro-3'-{[2-fluoro-4-(trifluorom...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50327103 (5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARalpha LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311794 (5-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)benzam...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50311793 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARalpha LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311793 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50327101 (5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARalpha LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311792 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311795 (4'-butoxy-2-fluoro-3'-((2-fluoro-4-(trifluoromethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50327103 (5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311791 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50327101 (5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%