Affinity Data by PubMed id=21316817

PubMed code 21316817

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340653 (3-(Indol-3-yl)-7-methoxycoumarin \| CHEMBL1761762) Show SMILES COc1ccc2cc(-c3c[nH]c4ccccc34)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340652 (7-Methoxy-3-(thiophen-3-yl)coumarin \| CHEMBL176176...) Show SMILES COc1ccc2cc(-c3ccsc3)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340659 (6-Methoxy-3-(thiophen-3-yl)coumarin \| CHEMBL176176...) Show SMILES COc1ccc2oc(=O)c(cc2c1)-c1ccsc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340657 (7-Methoxy-3-(thiophen-2-yl)coumarin \| CHEMBL176176...) Show SMILES COc1ccc2cc(-c3cccs3)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340658 (6-Methoxy-3-(thiophen-2-yl)coumarin \| CHEMBL176176...) Show SMILES COc1ccc2oc(=O)c(cc2c1)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	634	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340656 (3-(Indol-3-yl)coumarin \| CHEMBL1761759) Show SMILES O=c1oc2ccccc2cc1-c1c[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50340652 (7-Methoxy-3-(thiophen-3-yl)coumarin \| CHEMBL176176...) Show SMILES COc1ccc2cc(-c3ccsc3)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340654 (3-(Thiophen-2-yl)coumarin \| CHEMBL1761757) Show SMILES O=c1oc2ccccc2cc1-c1cccs1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM29136 (CHEMBL92401 \| Euphozid \| Iprazid \| Iproniazid) Show SMILES CC(C)NNC(=O)c1ccncc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM29136 (CHEMBL92401 \| Euphozid \| Iprazid \| Iproniazid) Show SMILES CC(C)NNC(=O)c1ccncc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50340653 (3-(Indol-3-yl)-7-methoxycoumarin \| CHEMBL1761762) Show SMILES COc1ccc2cc(-c3c[nH]c4ccccc34)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50340655 (3-(Thiophen-3-yl)coumarin \| CHEMBL1761758) Show SMILES O=c1oc2ccccc2cc1-c1ccsc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in BTI-TN-5B1-4 cells assessed as H2O2 production using para-tyramine substrate by fluorimetric metho...				Eur J Med Chem 46: 1147-52 (2011) Article DOI: 10.1016/j.ejmech.2011.01.033 BindingDB Entry DOI: 10.7270/Q25H7GKD
Universita degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%