Affinity Data by PubMed id=21428375

PubMed code 21428375

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcription factor p65 (Homo sapiens (Human))	BDBM50196926 (CHEMBL438139 \| Rocaglamide \| US10085988, Compound ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346334 (1,3,7-trihydroxy-2,4-diisoprenylxanthone \| CHEMBL1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346339 (4-Methyl-3,6-di-O-methyl-alpha-mangostin \| CHEMBL1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50214969 (1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346335 (CHEMBL1782241 \| Cochinchinone A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346336 (3-O-acetyl-alpha-mangostin \| CHEMBL1782242) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346338 (7-methoxy-2,8-bis(3-methylbut-2-enyl)-9-oxo-9H-xan...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346344 (7-O-Methylcochinchinone A \| CHEMBL1782582) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346345 (3,7-Di-O-methylcochinchinone A \| CHEMBL1782583) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346337 (3,6-di-O-acetyl-alpha-mangostin \| CHEMBL465553 \| d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346340 (3,6-di-O-methyl-alpha-mangostin \| CHEMBL464524 \| d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346341 (6-O-benzoyl-alpha-mangostin \| CHEMBL1782245) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346333 ((1S,3aR,5R,12aR)-3,3a,4,5-tetrahydro-8,10-dihydrox...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346346 (7-O-Benzoylcochinchinone A \| CHEMBL1782584) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346343 (3,7-Di-O-acetylcochinchinone A \| CHEMBL1782248) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50346342 (1-isomangostin hydrate \| CHEMBL1782247) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...				J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%