Affinity Data by PubMed id=21807515

PubMed code 21807515

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352509 (CHEMBL1824848) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352515 (CHEMBL1824850) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM60660 (2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352513 (CHEMBL1824853) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352512 (CHEMBL1824852) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352508 (CHEMBL1824847) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352510 (CHEMBL1824849) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352514 (CHEMBL1824854) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50352511 (CHEMBL1824851) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins				Bioorg Med Chem Lett 21: 5255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.07.036 BindingDB Entry DOI: 10.7270/Q2ZP46HX
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%