Found 29 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50059889
((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)Show SMILES CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50059889
((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)Show SMILES CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361920
(CHEMBL1938959)Show InChI InChI=1S/C14H12N4/c1-11-6-2-3-8-14(11)18-10-13(16-17-18)12-7-4-5-9-15-12/h2-10H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361919
(CHEMBL1938958)Show InChI InChI=1S/C14H12N4/c1-11-5-7-12(8-6-11)18-10-14(16-17-18)13-4-2-3-9-15-13/h2-10H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361917
(CHEMBL1938953)Show InChI InChI=1S/C13H9ClN4/c14-11-1-3-12(4-2-11)18-9-13(16-17-18)10-5-7-15-8-6-10/h1-9H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361911
(CHEMBL294410)Show InChI InChI=1S/C13H9FN4/c14-11-1-3-12(4-2-11)18-13(9-16-17-18)10-5-7-15-8-6-10/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361909
(CHEMBL62965)Show InChI InChI=1S/C13H9ClN4/c14-11-1-3-12(4-2-11)18-13(9-16-17-18)10-5-7-15-8-6-10/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361918
(CHEMBL1938954)Show InChI InChI=1S/C13H9ClN4/c14-11-2-1-3-12(8-11)18-9-13(16-17-18)10-4-6-15-7-5-10/h1-9H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361912
(CHEMBL63070)Show InChI InChI=1S/C14H12N4/c1-11-2-4-13(5-3-11)18-14(10-16-17-18)12-6-8-15-9-7-12/h2-10H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361914
(CHEMBL1938964)Show SMILES C1C2CC3CC1CC(C2)C3n1nncc1-c1ccncc1 |TLB:8:7:4:2.1.0,0:1:9:6.5.4,0:5:9:2.8.1,THB:8:1:9.7.6:4,10:9:4:2.1.0,(12.18,-2.43,;12.28,-3.87,;10.83,-4.39,;9.35,-3.96,;9.3,-2.44,;10.75,-1.91,;9.75,-3.09,;9.76,-4.63,;11.22,-5.09,;8.32,-5.23,;7.01,-6.05,;6.96,-7.59,;5.52,-8.02,;4.64,-6.76,;5.58,-5.54,;5.01,-4.09,;5.78,-2.75,;5,-1.43,;3.44,-1.46,;2.7,-2.78,;3.48,-4.11,)| Show InChI InChI=1S/C17H20N4/c1-3-18-4-2-13(1)16-10-19-20-21(16)17-14-6-11-5-12(8-14)9-15(17)7-11/h1-4,10-12,14-15,17H,5-9H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361916
(CHEMBL1938966)Show SMILES C1C2CC3CC1CC(C2)C3n1nncc1-c1ccc2nccnc2c1 |TLB:0:1:9:6.5.4,0:5:9:2.8.1,8:7:4:2.1.0,THB:10:9:4:2.1.0,8:1:9.7.6:4,(9.62,-8.52,;9.68,-9.96,;8.21,-10.42,;6.75,-9.94,;6.75,-8.42,;8.22,-7.95,;7.18,-9.08,;7.12,-10.63,;8.57,-11.14,;5.66,-11.17,;4.29,-11.88,;4.33,-13.43,;2.91,-13.94,;1.96,-12.72,;2.84,-11.45,;2.41,-9.96,;3.23,-8.65,;2.5,-7.3,;.96,-7.25,;.23,-5.89,;-1.31,-5.85,;-2.12,-7.17,;-1.39,-8.52,;.15,-8.56,;.87,-9.91,)| Show InChI InChI=1S/C20H21N5/c1-2-17-18(22-4-3-21-17)10-14(1)19-11-23-24-25(19)20-15-6-12-5-13(8-15)9-16(20)7-12/h1-4,10-13,15-16,20H,5-9H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361916
(CHEMBL1938966)Show SMILES C1C2CC3CC1CC(C2)C3n1nncc1-c1ccc2nccnc2c1 |TLB:0:1:9:6.5.4,0:5:9:2.8.1,8:7:4:2.1.0,THB:10:9:4:2.1.0,8:1:9.7.6:4,(9.62,-8.52,;9.68,-9.96,;8.21,-10.42,;6.75,-9.94,;6.75,-8.42,;8.22,-7.95,;7.18,-9.08,;7.12,-10.63,;8.57,-11.14,;5.66,-11.17,;4.29,-11.88,;4.33,-13.43,;2.91,-13.94,;1.96,-12.72,;2.84,-11.45,;2.41,-9.96,;3.23,-8.65,;2.5,-7.3,;.96,-7.25,;.23,-5.89,;-1.31,-5.85,;-2.12,-7.17,;-1.39,-8.52,;.15,-8.56,;.87,-9.91,)| Show InChI InChI=1S/C20H21N5/c1-2-17-18(22-4-3-21-17)10-14(1)19-11-23-24-25(19)20-15-6-12-5-13(8-15)9-16(20)7-12/h1-4,10-13,15-16,20H,5-9H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361910
(CHEMBL303351)Show InChI InChI=1S/C13H9ClN4/c14-11-2-1-3-12(8-11)18-13(9-16-17-18)10-4-6-15-7-5-10/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361914
(CHEMBL1938964)Show SMILES C1C2CC3CC1CC(C2)C3n1nncc1-c1ccncc1 |TLB:8:7:4:2.1.0,0:1:9:6.5.4,0:5:9:2.8.1,THB:8:1:9.7.6:4,10:9:4:2.1.0,(12.18,-2.43,;12.28,-3.87,;10.83,-4.39,;9.35,-3.96,;9.3,-2.44,;10.75,-1.91,;9.75,-3.09,;9.76,-4.63,;11.22,-5.09,;8.32,-5.23,;7.01,-6.05,;6.96,-7.59,;5.52,-8.02,;4.64,-6.76,;5.58,-5.54,;5.01,-4.09,;5.78,-2.75,;5,-1.43,;3.44,-1.46,;2.7,-2.78,;3.48,-4.11,)| Show InChI InChI=1S/C17H20N4/c1-3-18-4-2-13(1)16-10-19-20-21(16)17-14-6-11-5-12(8-14)9-15(17)7-11/h1-4,10-12,14-15,17H,5-9H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361917
(CHEMBL1938953)Show InChI InChI=1S/C13H9ClN4/c14-11-1-3-12(4-2-11)18-9-13(16-17-18)10-5-7-15-8-6-10/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361913
(CHEMBL1938963)Show InChI InChI=1S/C14H12N4/c1-11-4-2-3-5-13(11)18-14(10-16-17-18)12-6-8-15-9-7-12/h2-10H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361923
(CHEMBL1938956)Show InChI InChI=1S/C13H9ClN4/c14-10-4-6-11(7-5-10)18-9-13(16-17-18)12-3-1-2-8-15-12/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361913
(CHEMBL1938963)Show InChI InChI=1S/C14H12N4/c1-11-4-2-3-5-13(11)18-14(10-16-17-18)12-6-8-15-9-7-12/h2-10H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361921
(CHEMBL1938402)Show InChI InChI=1S/C17H13N5/c1-2-4-13(5-3-1)11-22-12-17(20-21-22)14-6-7-15-16(10-14)19-9-8-18-15/h1-10,12H,11H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361922
(CHEMBL1938955)Show InChI InChI=1S/C14H12N4/c1-11-2-4-13(5-3-11)18-10-14(16-17-18)12-6-8-15-9-7-12/h2-10H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361924
(CHEMBL1938957)Show InChI InChI=1S/C13H9FN4/c14-10-4-6-11(7-5-10)18-9-13(16-17-18)12-3-1-2-8-15-12/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361920
(CHEMBL1938959)Show InChI InChI=1S/C14H12N4/c1-11-6-2-3-8-14(11)18-10-13(16-17-18)12-7-4-5-9-15-12/h2-10H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361921
(CHEMBL1938402)Show InChI InChI=1S/C17H13N5/c1-2-4-13(5-3-1)11-22-12-17(20-21-22)14-6-7-15-16(10-14)19-9-8-18-15/h1-10,12H,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361907
(CHEMBL1938961)Show SMILES C1C2CC3CC1CC(C2)C3n1cc(nn1)-c1ccc2nccnc2c1 |TLB:8:7:4:2.1.0,0:1:9:6.5.4,0:5:9:2.8.1,10:9:4:2.1.0,THB:8:1:9.7.6:4,10:9:2.8.1:6.5.4,(17.39,-21.23,;15.86,-21.17,;15.56,-19.76,;16.1,-18.45,;17.59,-18.49,;18.02,-19.86,;16.83,-18.77,;15.24,-18.72,;14.62,-20.1,;14.87,-17.2,;13.34,-17.22,;12.42,-15.99,;10.96,-16.48,;10.98,-18.02,;12.45,-18.48,;9.62,-15.72,;9.62,-14.17,;8.28,-13.41,;6.95,-14.19,;5.61,-13.43,;4.28,-14.21,;4.29,-15.77,;5.64,-16.52,;6.96,-15.74,;8.3,-16.49,)| Show InChI InChI=1S/C20H21N5/c1-2-17-18(22-4-3-21-17)10-14(1)19-11-25(24-23-19)20-15-6-12-5-13(8-15)9-16(20)7-12/h1-4,10-13,15-16,20H,5-9H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361915
(CHEMBL1938965)Show SMILES C1C2CC3CC1CC(C2)C3n1nncc1-c1ccccn1 |TLB:8:7:4:2.1.0,0:1:9:6.5.4,0:5:9:2.8.1,10:9:2.8.1:6.5.4,THB:8:1:9.7.6:4,10:9:4:2.1.0,(10.67,-3.77,;10.73,-5.21,;9.26,-5.67,;7.8,-5.19,;7.8,-3.67,;9.26,-3.2,;8.23,-4.34,;8.18,-5.88,;9.63,-6.39,;6.72,-6.43,;5.23,-6.82,;4.72,-8.28,;3.22,-8.26,;2.76,-6.79,;4.02,-5.9,;4.01,-4.36,;2.68,-3.59,;2.67,-2.05,;3.98,-1.29,;5.34,-2.05,;5.35,-3.58,)| Show InChI InChI=1S/C17H20N4/c1-2-4-18-15(3-1)16-10-19-20-21(16)17-13-6-11-5-12(8-13)9-14(17)7-11/h1-4,10-14,17H,5-9H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361918
(CHEMBL1938954)Show InChI InChI=1S/C13H9ClN4/c14-11-2-1-3-12(8-11)18-9-13(16-17-18)10-4-6-15-7-5-10/h1-9H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361908
(CHEMBL1938962)Show InChI InChI=1S/C16H18N6O/c1-2-14-15(18-4-3-17-14)11-13(1)16-12-22(20-19-16)6-5-21-7-9-23-10-8-21/h1-4,11-12H,5-10H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50361925
(CHEMBL1938960)Show InChI InChI=1S/C16H10FN5/c17-12-2-4-13(5-3-12)22-10-16(20-21-22)11-1-6-14-15(9-11)19-8-7-18-14/h1-10H | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50361919
(CHEMBL1938958)Show InChI InChI=1S/C14H12N4/c1-11-5-7-12(8-6-11)18-10-14(16-17-18)13-4-2-3-9-15-13/h2-10H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta by colorimetric analysis |
Bioorg Med Chem Lett 22: 591-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.076
BindingDB Entry DOI: 10.7270/Q2JQ11GW |
More data for this
Ligand-Target Pair | |
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