Affinity Data by PubMed id=22421018

PubMed code 22421018

Found 34 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380711 (CHEMBL2017668) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380694 (CHEMBL2017510) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380713 (CHEMBL2017671) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380709 (CHEMBL2017665) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380692 (CHEMBL2017508) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380701 (CHEMBL2017657) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380702 (CHEMBL2017658) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380696 (CHEMBL2017512) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380693 (CHEMBL2017509) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380707 (CHEMBL2017663) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380705 (CHEMBL2017661) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380687 (CHEMBL2017502) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380698 (CHEMBL2017514) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380714 (CHEMBL2017672) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380697 (CHEMBL2017513) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380695 (CHEMBL2017511) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380708 (CHEMBL2017664) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380710 (CHEMBL2017667) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380712 (CHEMBL2017670) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380690 (CHEMBL2017505) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380700 (CHEMBL2017656) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380689 (CHEMBL2017504) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380703 (CHEMBL2017659) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380684 (CHEMBL2017666) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380683 (CHEMBL2017507) Show SMILES CCOP(=O)(OCC)C(Cc1ccccc1)c1sc2ccccc2c1C Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380699 (CHEMBL2017655) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380706 (CHEMBL2017662) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380688 (CHEMBL2017503) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380691 (CHEMBL2017506) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380704 (CHEMBL2017660) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380686 (CHEMBL2017501) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380716 (CHEMBL2016589) Show SMILES CCOP(=O)(OCC)C(Cc1ccc(Br)cc1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380685 (CHEMBL2017500) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380715 (CHEMBL2017673) Show SMILES CCOP(=O)(OCC)C(c1ccccc1)c1ccc(Br)cc1 Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%