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PubMed code 22507960

Compile data set for download or QSAR
Found 26 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acrosin


(Homo sapiens (Human))		BDBM50382108
PNG
(CHEMBL2023317)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)N(CCC(C)C)CCC(C)C
Show InChI InChI=1S/C19H30N4O4S/c1-13(2)8-10-23(11-9-14(3)4)28(25,26)15-6-7-16-17(12-15)21-18(20-16)22-19(24)27-5/h6-7,12-14H,8-11H2,1-5H3,(H2,20,21,22,24)
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n/an/a 6.30E+4n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382090
PNG
(CHEMBL2022136)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccccc1F
Show InChI InChI=1S/C16H15FN4O4S/c1-25-16(22)21-15-19-13-7-6-11(8-14(13)20-15)26(23,24)18-9-10-4-2-3-5-12(10)17/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 3.10E+5n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382105
PNG
(CHEMBL2023314)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NC(C)C
Show InChI InChI=1S/C12H16N4O4S/c1-7(2)16-21(18,19)8-4-5-9-10(6-8)14-11(13-9)15-12(17)20-3/h4-7,16H,1-3H3,(H2,13,14,15,17)
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n/an/a 4.70E+5n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382099
PNG
(CHEMBL2023306)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccccc1
Show InChI InChI=1S/C16H16N4O4S/c1-24-16(21)20-15-18-13-8-7-12(9-14(13)19-15)25(22,23)17-10-11-5-3-2-4-6-11/h2-9,17H,10H2,1H3,(H2,18,19,20,21)
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n/an/a 1.03E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382113
PNG
(CHEMBL2023318)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)N(C)Cc1ccccc1
Show InChI InChI=1S/C17H18N4O4S/c1-21(11-12-6-4-3-5-7-12)26(23,24)13-8-9-14-15(10-13)19-16(18-14)20-17(22)25-2/h3-10H,11H2,1-2H3,(H2,18,19,20,22)
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n/an/a 1.25E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382095
PNG
(CHEMBL2022141)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C16H14Cl2N4O4S/c1-26-16(23)22-15-20-13-5-4-11(7-14(13)21-15)27(24,25)19-8-9-2-3-10(17)6-12(9)18/h2-7,19H,8H2,1H3,(H2,20,21,22,23)
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n/an/a 1.27E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382111
PNG
(CHEMBL2023308)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(F)cc1F
Show InChI InChI=1S/C16H14F2N4O4S/c1-26-16(23)22-15-20-13-5-4-11(7-14(13)21-15)27(24,25)19-8-9-2-3-10(17)6-12(9)18/h2-7,19H,8H2,1H3,(H2,20,21,22,23)
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n/an/a 1.55E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382101
PNG
(CHEMBL2023309)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(F)c(F)c1
Show InChI InChI=1S/C16H14F2N4O4S/c1-26-16(23)22-15-20-13-5-3-10(7-14(13)21-15)27(24,25)19-8-9-2-4-11(17)12(18)6-9/h2-7,19H,8H2,1H3,(H2,20,21,22,23)
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n/an/a 1.59E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382092
PNG
(CHEMBL2022138)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C16H15BrN4O4S/c1-25-16(22)21-15-19-13-7-6-12(8-14(13)20-15)26(23,24)18-9-10-2-4-11(17)5-3-10/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 1.64E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382109
PNG
(CHEMBL2023319)
Show SMILES Clc1ccc(-c2cc(C=O)no2)c(Cl)c1
Show InChI InChI=1S/C10H5Cl2NO2/c11-6-1-2-8(9(12)3-6)10-4-7(5-14)13-15-10/h1-5H
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n/an/a 1.70E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382106
PNG
(CHEMBL2023315)
Show SMILES CCCCNS(=O)(=O)c1ccc2nc(NC(=O)OC)[nH]c2c1
Show InChI InChI=1S/C13H18N4O4S/c1-3-4-7-14-22(19,20)9-5-6-10-11(8-9)16-12(15-10)17-13(18)21-2/h5-6,8,14H,3-4,7H2,1-2H3,(H2,15,16,17,18)
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n/an/a 1.77E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382107
PNG
(CHEMBL2023316)
Show SMILES CCCCCCNS(=O)(=O)c1ccc2nc(NC(=O)OC)[nH]c2c1
Show InChI InChI=1S/C15H22N4O4S/c1-3-4-5-6-9-16-24(21,22)11-7-8-12-13(10-11)18-14(17-12)19-15(20)23-2/h7-8,10,16H,3-6,9H2,1-2H3,(H2,17,18,19,20)
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n/an/a 1.80E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382102
PNG
(CHEMBL2023310)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1cccc(F)c1
Show InChI InChI=1S/C16H15FN4O4S/c1-25-16(22)21-15-19-13-6-5-12(8-14(13)20-15)26(23,24)18-9-10-3-2-4-11(17)7-10/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 1.81E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382091
PNG
(CHEMBL2022137)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C16H15FN4O4S/c1-25-16(22)21-15-19-13-7-6-12(8-14(13)20-15)26(23,24)18-9-10-2-4-11(17)5-3-10/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 2.40E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382098
PNG
(CHEMBL2023305)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(C)cc1
Show InChI InChI=1S/C17H18N4O4S/c1-11-3-5-12(6-4-11)10-18-26(23,24)13-7-8-14-15(9-13)20-16(19-14)21-17(22)25-2/h3-9,18H,10H2,1-2H3,(H2,19,20,21,22)
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n/an/a 3.18E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382110
PNG
(CHEMBL2022143)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(OC)cc1
Show InChI InChI=1S/C17H18N4O5S/c1-25-12-5-3-11(4-6-12)10-18-27(23,24)13-7-8-14-15(9-13)20-16(19-14)21-17(22)26-2/h3-9,18H,10H2,1-2H3,(H2,19,20,21,22)
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n/an/a 3.29E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382096
PNG
(CHEMBL2022142)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H14Cl2N4O4S/c1-26-16(23)22-15-20-13-5-3-10(7-14(13)21-15)27(24,25)19-8-9-2-4-11(17)12(18)6-9/h2-7,19H,8H2,1H3,(H2,20,21,22,23)
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n/an/a 4.02E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382097
PNG
(CHEMBL2023304)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1cccc(C)c1
Show InChI InChI=1S/C17H18N4O4S/c1-11-4-3-5-12(8-11)10-18-26(23,24)13-6-7-14-15(9-13)20-16(19-14)21-17(22)25-2/h3-9,18H,10H2,1-2H3,(H2,19,20,21,22)
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n/an/a 5.06E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382093
PNG
(CHEMBL2022139)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccccc1Cl
Show InChI InChI=1S/C16H15ClN4O4S/c1-25-16(22)21-15-19-13-7-6-11(8-14(13)20-15)26(23,24)18-9-10-4-2-3-5-12(10)17/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 5.75E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382104
PNG
(CHEMBL2023312)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1cccc(OC)c1
Show InChI InChI=1S/C17H18N4O5S/c1-25-12-5-3-4-11(8-12)10-18-27(23,24)13-6-7-14-15(9-13)20-16(19-14)21-17(22)26-2/h3-9,18H,10H2,1-2H3,(H2,19,20,21,22)
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n/an/a 7.50E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382094
PNG
(CHEMBL2022140)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C16H15ClN4O4S/c1-25-16(22)21-15-19-13-7-6-12(8-14(13)20-15)26(23,24)18-9-10-2-4-11(17)5-3-10/h2-8,18H,9H2,1H3,(H2,19,20,21,22)
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n/an/a 7.52E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382103
PNG
(CHEMBL2023311)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccccc1OC
Show InChI InChI=1S/C17H18N4O5S/c1-25-15-6-4-3-5-11(15)10-18-27(23,24)12-7-8-13-14(9-12)20-16(19-13)21-17(22)26-2/h3-9,18H,10H2,1-2H3,(H2,19,20,21,22)
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n/an/a 8.42E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382089
PNG
(CHEMBL2022135)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)Nc1cc(C)ccc1C
Show InChI InChI=1S/C17H18N4O4S/c1-10-4-5-11(2)14(8-10)21-26(23,24)12-6-7-13-15(9-12)19-16(18-13)20-17(22)25-3/h4-9,21H,1-3H3,(H2,18,19,20,22)
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n/an/a 8.86E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382100
PNG
(CHEMBL2023307)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N4O4S/c1-28-16(25)24-15-22-13-7-6-12(8-14(13)23-15)29(26,27)21-9-10-2-4-11(5-3-10)17(18,19)20/h2-8,21H,9H2,1H3,(H2,22,23,24,25)
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n/an/a 1.07E+7n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50382112
PNG
(CHEMBL2023313)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(OC)c(OC)c1
Show InChI InChI=1S/C18H20N4O6S/c1-26-15-7-4-11(8-16(15)27-2)10-19-29(24,25)12-5-6-13-14(9-12)21-17(20-13)22-18(23)28-3/h4-9,19H,10H2,1-3H3,(H2,20,21,22,23)
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n/an/a 1.15E+7n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
Acrosin


(Homo sapiens (Human))		BDBM50354886
PNG
(CHEMBL466465)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl |r|
Show InChI InChI=1S/C14H21ClN2O3S/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16/h5-8,13,17H,2-4,9-10,16H2,1H3/t13-/m0/s1
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n/an/a 1.43E+8n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%