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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human)) | BDBM50425824 (CHEMBL2312289) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Biotechnology Center San Diego Curated by ChEMBL | Assay Description Inhibition of full length SIRT1 (unknown origin) by fluorometric enzyme assay | J Med Chem 56: 963-9 (2013) Article DOI: 10.1021/jm301431y BindingDB Entry DOI: 10.7270/Q2B56M22 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human)) | BDBM50425824 (CHEMBL2312289) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Lilly Biotechnology Center San Diego Curated by ChEMBL | Assay Description Binding affinity to C-terminally His-tagged SIRT1 catalytic domain (241 to 516 amino acid residues plus EGHHHHHH) (unknown origin) expressed in bacul... | J Med Chem 56: 963-9 (2013) Article DOI: 10.1021/jm301431y BindingDB Entry DOI: 10.7270/Q2B56M22 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
